VisualSonics Vevo® 2100 Imaging System Operator Manual
VisualSonics Inc. VisualSonics—North America VisualSonics—Europe 3080 Yonge Street, Suite 6100 VisualSonics Europe Box 66 Kruislaan 406 Toronto, Ontario Matrix V Canada Suite 412 M4N 3N1 1098 SM Amsterdam Tel: +1 (416) 484-5000 The Netherlands Toll-Free: 1-866-416-4636 (North America) Tel: +31 (0) 20 751 2020 Fax: +1 (416) 484-5001 Toll-Free: +800 0751 2020 Fax: +31 (0) 20 751 2021 www.visualsonics.com | support@visualsonics.com Copyright © 2001-2008 by VisualSonics Inc.
Contents Getting started 13 Introduction ............................................................................................14 Operator Manual conventions ....................................................................14 System description ................................................................................16 Cart description.............................................................................................16 Vevo 2100 Workstation Software description .................
Export and Copy To windows workspaces ..............................................54 Control panel ..........................................................................................57 Control groupings ........................................................................................57 Vevo Imaging Station .............................................................................58 Managing operator access 60 Working with operator profiles...............................................
Setting the Operator tab preferences ...................................................79 Setting the Measurement tab preferences ...........................................80 Measurement Package preferences ............................................................80 Measurement Parameters preferences.......................................................84 Measurement Display preferences.............................................................85 Setting the Annotation tab preferences...............
Setting up to acquire physiological data............................................109 Physiological data sources.........................................................................109 Connecting the blood pressure equipment.............................................110 Configuring the physiology data display settings.................................110 Acquiring image data ...........................................................................120 Saving image data ..............................
Exporting images to DICOM from the Study Browser .........................145 Exporting the Study Browser list view as a text file ..............................148 Exporting the Study Browser window content......................................149 Copying, deleting and importing.........................................................152 Copying studies, series or images ............................................................152 Deleting studies, series or images ......................................
Working with annotations....................................................................175 Annotation workspace...............................................................................175 Predefined annotations ..............................................................................176 Adding annotations....................................................................................180 Modifying annotations...............................................................................
Setting the M-Mode region of interest.....................................................234 Analyzing M-Mode images...................................................................235 Adding generic M-Mode measurements ................................................235 Adding protocol measurements ...............................................................239 Creating pressure-volume loop measurements in M-Mode ................
Setting up for a 3D-Mode image acquisition ..........................................282 Recording a 3D-Mode analysis session ...................................................286 Analyzing 3D-Mode images .................................................................288 3D-Mode visualization tools .....................................................................288 Manipulating 3D-Mode image data.........................................................290 Creating 3D volume measurements.............
Contrast Mode imaging and analysis 337 Acquiring Contrast Mode images .......................................................338 Typical Contrast Mode image acquisition session.................................338 Typical Contrast 3D-Mode image acquisition........................................341 Contrast Mode window workspace.........................................................343 Control panel controls for Contrast Mode ..............................................
Descriptions of control panel controls ...............................................406 Image Sequence...........................................................................................412 Options and accessories .....................................................................422 Supplier ........................................................................................................426 Product safety testing and electrical testing .....................................427 Safety......
Section 1 Getting started This section introduces you to the Vevo 2100 Imaging System. In this section Introduction ...........................................................................................................................14 System description ................................................................................................................16 Quick Start Tutorial...............................................................................................................
Chapter 1: Introduction Chapter 1 Introduction Thank you for using the Vevo® Imaging System, the high-resolution in vivo micro imaging system from VisualSonics®.
Chapter 1: Introduction Bold Selections you make when you are using the software Subheadings Names of power switches and rear panel connectors Labels (such as Tip:) Column headings in a table Keywords and parameters in text Control Block Control panel keys, dials, toggles, sliders. Italic Cross references Menu paths Citations (titles of books, diskettes, and CDs) Terms defined in text Variables and values that you must provide Monospace Rev 1.
Chapter 2: System description Chapter 2 System description The Vevo 2100 Imaging System enables in vivo visualization, assessment, and measurement of anatomical structures and hemodynamic function in longitudinal imaging studies for small animal phenotyping. In this chapter Cart description .....................................................................................................................16 Vevo 2100 Workstation Software description .......................................................
Chapter 2: System description Front view of the Vevo 2100 Imaging System 24" LCD monitor Air vent (x2) Speakers (x2) DVD drive Transducer Control panel Transducer and gel holder Grab bar Transducer ports (1 active, 2 passive) Replaceable air filter Lockable castor (x4) Rev 1.
Chapter 2: System description Rear view of the Vevo 2100 Imaging System 3-way monitor positioning arm 24" LCD monitor ECG/Physio 10-pin locking connector Firewire connector 3D motor connector USB connector (x3) Parallel port DVI connector Main power switch Computer power switch Power cable DVD drive BNC connectors (for future use) S-Video connector Lockable castor (x4) 18 Air filter VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 2: System description MicroScan™ transducer The MicroScan™ array transducer (the transducer) is the device you use to acquire real-time visualization of the hemodynamic or anatomical target. The unit is designed as a hand-held probe for rapid screening procedures. You can attach it to the Vevo Imaging Station. The components of the integrated transducer system are displayed in the following illustration.
Chapter 2: System description The features of the transducer are displayed in the following illustration. 0º, 90º, 180º, 270º collar dimples Housing Array Transducer options VisualSonics offers five transducers with center frequencies ranging from 12.5MHz to 45MHz to serve applications ranging from rabbit to mouse.
Chapter 2: System description Front panel The front panel of the Vevo 2100 Imaging System features three transducer ports and a transducer cable holder, as shown in the following illustration. Related information Connecting and disconnecting the transducer (page 106) Rear panel The rear panel provides the connectors and power controls as detailed in the following illustration.
Chapter 2: System description Rear panel connector Description Main power switch After the power cable is connected, push the switch up to power the Vevo 2100 Imaging System. WARNING: Do not modify the attachment plug or use an adapter. This could cause an electrical hazard. If you need to use a different plug, contact a Technical Support Representative at 1866-416-4636 (North America, toll-free), +800 0751 2020 (Europe, toll-free) or by email at support@visualsonics.com.
Chapter 2: System description Related information Turning your system On and Off (page 34) Accessories (page 422) Connecting the blood pressure equipment (page 110) Connecting the 3D motor stage to the Vevo Imaging Station (page 102) Control panel The control panel provides all image acquisition controls as well as the primary study management controls. The control panel also provides variable backlighting under the keys and controls.
Chapter 2: System description Grab bars Use the front and back grab bars when you are moving the system. Don't use them to lift the system. They are not designed to bear the weight of the system. Transducer and gel holder Use the transducer or gel holders located on the left and right sides of the cart to store your transducers and gel bottles. Store both items facing up. Castors Castors allow the Vevo 2100 Imaging System to be moved easily.
Chapter 2: System description Air filters The Vevo 2100 Imaging System includes three air filters as described in the following illustration. Rear panel air filter Frame base air filter (rear). An identical frame base air filter is situated at the front WARNING: Do not obstruct or block the filter inlets; overheating of the electronics could occur. Related information Cleaning your air filters (page 440) Vents The cart includes six air vents.
Chapter 2: System description Use it to read or write data to and from CDs and DVDs. The system also provides USB, Firewire and S-Video connectors on the rear panel so you can export image data to a wide range of external devices. Note: The S-Video connection may not be active on your cart, depending on the configuration. Some internal configuration may be required. Contact VisualSonics for more information.
Chapter 2: System description Speakers Integrated speakers provide an audio representation of the blood flow acquired in PW Doppler Mode to complement the image on the PW Doppler spectral display. Isolation transformer The isolation transformer that powers the Vevo 2100 Imaging System is located inside the Vevo 2100 Imaging System. The isolation transformer protects you and the equipment from electrical shock and power surges.
Chapter 2: System description CAUTION: Before connecting the system ensure the voltage is correct. Ensure the power cable is undamaged before plugging the system directly into the wall outlet. Use of an extension cord or a power bar is discouraged. The voltage is specified on the power connection plate on the rear panel of the system.
Chapter 2: System description Available configurations VisualSonics offers several configurations of the Vevo 2100 Imaging System, as described in the following table.
Chapter 3: Quick Start Tutorial Chapter 3 Quick Start Tutorial This chapter is a high-level procedure for acquiring and analyzing an image and then exporting your analysis. You will find this quick start tutorial useful: If you are familiar with how ultrasound systems work and you want to jump in and give it a try If you haven't used the system in a while and want a refresher tutorial Before you begin Ensure that you have connected a transducer to the transducer port on the front of the cart.
Chapter 3: Quick Start Tutorial The system creates a date-stamped new study for you as well as the first image series set, Series 1. The system stores a date-stamped cine loop of the B-Mode data you are acquiring Scan/Freeze 8. Press again to resume the data acquisition. 9. Continue freezing and storing as required. 10. Press Study Management . The Study Browser window appears and displays the new date-stamped study, new date-stamped study series and the new time-stamped images.
Chapter 3: Quick Start Tutorial When you have completed your measurement, the system applies a label or index number to your measurement based on the preferences you set in the Measurement tab of the Preferences window. The system also displays the value in the Measured Values list. 17. Press Study Management . The Study Browser appears. The thumbnail of the image you have been adding measurements to displays the most recent frame you worked on, including the measurements. 18.
Section 2 Vevo fundamentals This section introduces you to the fundamentals of the Vevo 2100 Imaging System and shows you how they work. In This Section How the Vevo 2100 Imaging System works ......................................................................34 Logging on .............................................................................................................................41 Vevo 2100 Imaging System workspaces........................................................................
Chapter 4: How the Vevo 2100 Imaging System works Chapter 4 How the Vevo 2100 Imaging System works The Vevo 2100 Imaging System is easy to work with and understand because you work with three simple concepts: Image acquisition modes Operators Studies WARNING: Before using the VEVO 2100 any operator must read and observe the safety warnings and precautions in Safety (page 429). This chapter shows you how these concepts work together to help you generate useful image data.
Chapter 4: How the Vevo 2100 Imaging System works CAUTION: Before connecting the system ensure the voltage is correct. Ensure the power cable is undamaged before plugging the system directly into the wall outlet. Use of an extension cord or a power bar is discouraged. The voltage is specified on the power connection plate on the rear panel of the system. f To turn your system ON: 1. On the rear panel, push up the Main Power switch.
Chapter 4: How the Vevo 2100 Imaging System works Application packages Application packages are predefined groups of image acquisition settings. This way you can quickly get an optimal image to work with, and when you're ready to take your measurements, you can quickly cycle through the pre-ordered measurements protocol for your application.
Chapter 4: How the Vevo 2100 Imaging System works Studies, series and images Studies in the Vevo 2100 Imaging System are like studies in a paper based system. They work much like a file directory and hold all the series of images that are part of your study. Studies are composed of one or more grouped image sets called series, and the series are composed of one or more images (individual frames and/or multipleframe cine loops).
Chapter 4: How the Vevo 2100 Imaging System works M-Mode overview M-Mode is used primarily to measure the movement and dimensions of cardiac structures such as chambers and walls. M-Mode works fundamentally differently than B-Mode. Where B-Mode uses multiple scanning beams to create its image, M-Mode uses just one. So, when you have guided your transducer beam to the depth that gives you a proper cross-section of the heart, you can then set M-Mode to lay its single beam across that cross-section.
Chapter 4: How the Vevo 2100 Imaging System works Identifying vascular structures that can be more difficult to identify in other ultrasound mode image data Related information Mode window workspace (page 44) Acquiring Color Doppler Mode images (page 305) Analyzing Color Doppler Mode images (page 315) 3D-Mode overview 3D-Mode provides a three-dimensional view of an area of interest.
Chapter 4: How the Vevo 2100 Imaging System works Targeted molecular imaging for visualizing and quantifying the expression of intravascular molecular markers — for example: angiogenesis and inflammation Tumor perfusion and relative quantification of vascular volume and structure Assessment of myocardial perfusion and area of infarction Related information 40 Mode window workspace (page 44) Acquiring Contrast Mode images (page 338) Analyzing Contrast Mode images (page 352) VisualS
Chapter 5: Logging on Chapter 5 Logging on This chapter walks you through the procedures for logging on to the system and selecting yourself as the active operator. In this chapter Logging on the very first time the system is used ............................................................41 Logging on for a typical session ..........................................................................................
Chapter 5: Logging on CAUTION: If you do not create at least one Administrator operator as part of your operator group, any operator can add or delete other operators' studies. Next steps Adding an administrator (page 62) Adding an operator (page 63) Related information Logging on for a typical session (page 42) Application packages (page 36) Logging on for a typical session Use the following procedure after the administrator has created your operator profile.
Chapter 5: Logging on The system initializes the transducer and opens the Study Browser window. 4. In the Study Browser window, select your operator name. Any acquisition work you do – such as creating a new study, or a new series, or creating new images – is recorded by the system as being completed by this operator. Related information Rev 1.
Chapter 6: Vevo 2100 Imaging System workspaces Chapter 6 Vevo 2100 Imaging System workspaces This chapter describes the primary software workspaces that you use when you work with the Vevo 2100 Imaging System. In this chapter Mode window workspace....................................................................................................44 Study Browser window workspace ....................................................................................49 Study Information window workspace........
Chapter 6: Vevo 2100 Imaging System workspaces The following illustration and table describes the information and features in the Mode window. A typical Mode window workspace. This example is a B-Mode window displaying a stored cine loop. Area Description Image data panel. Displays the image data that the transducer produces, and displays the physiological data if you are acquiring it.
Chapter 6: Vevo 2100 Imaging System workspaces Area Description Dynamic range bar. Indicates the dynamic range of the display. When you acquire data, use the Dynamic Range control on the control panel to change the range. Physiological data trace panel. Displays your animal's dynamic heart rate, temperature, respiration rate and blood pressure data. This information comes from the Advanced Physiological Monitoring Unit that connects to the Vevo Imaging Station. Physiological data values.
Chapter 6: Vevo 2100 Imaging System workspaces Area Description Image details Displays the system default study name and series name (unless you have customized them in the Study Information section of the Study Information window). Displays the Animal ID if you added it in the Series Information section of the Study Information window. Displays the image label if you added it by pressing Image Label .
Chapter 6: Vevo 2100 Imaging System workspaces f To select the panel workspace you want to work with: Press the appropriate key on the control panel as described in the following illustration and table. Area Description Mode Settings panel workspace. Read-only. Press Mode Settings . Measurements panel workspace. Tools are only available when you are reviewing an individual frame and you pause the playback. During image acquisition, the tools are not available.
Chapter 6: Vevo 2100 Imaging System workspaces Study Browser window workspace The Study Browser window is the exploration workspace you use to manage your studies, study series, and individual images.
Chapter 6: Vevo 2100 Imaging System workspaces Area Description Series listing within a study. Image listing within a series. Operator selection list. Study Browser window commands. Image thumbnails or study notes for the selected series.
Chapter 6: Vevo 2100 Imaging System workspaces The following illustration and table describes the information and features in the Study Information window. Study Information window displaying the view when you select a series and then press Study Info . Area Description Study Information section. Includes the information boxes that describe a study. Series Information section. Includes the information boxes that describe a series within a study. Study Information window commands.
Chapter 6: Vevo 2100 Imaging System workspaces In the Study Browser, click Prefs. If you are analyzing data in a Mode window on the workstation, click the icon in the image tools icon panel. The following illustration and table describes the information and features in the Preferences window. Preferences window, displaying the General tab preference sections Area Description General preferences tab. Use this tab primarily to specify your acquisition settings. Operator preferences tab.
Chapter 6: Vevo 2100 Imaging System workspaces Responsibilities for administrators, owners and operators (page 61) Analysis Browser window workspace The Analysis Browser window displays a report of the measurements and calculations for one or more studies or just the study series you select in the Study Browser. f To open the Analysis Browser window: 1. Press Study Management . The system displays the Study Browser. 2. Select a study listing or study series listing and click Report.
Chapter 6: Vevo 2100 Imaging System workspaces Area Description Report details. If you select a study listing in the Study Browser before you click Analysis, the report details display all the measurements and calculations for all images in all series in the study. If you select a series listing in the Study Browser before you click Analysis, the report details displays only the measurements and calculations for the images in that series. Analysis Browser window commands. Image thumbnails.
Chapter 6: Vevo 2100 Imaging System workspaces The following illustration and table describes the information and features in the Export window. Export Image window displaying the export information and setup options for an image Area Description Folder browser. Functions the same way your Explorer window works on your Windows PC: browse the folders to find your destination folder. File transfer information and options.
Chapter 6: Vevo 2100 Imaging System workspaces Related information 56 Exporting images (page 139) Exporting measurements and calculations (page 185) VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 7: Control panel Chapter 7 Control panel This chapter describes the physical controls on the cart's control panel that you use to complete your image acquisition and image analysis tasks. In this chapter Control groupings .................................................................................................................
Chapter 8: Vevo Imaging Station Chapter 8 Vevo Imaging Station The Vevo® Imaging Station is VisualSonics’ advanced system for handling, monitoring and managing mice and rats during imaging procedures.
Chapter 8: Vevo Imaging Station Area Description Animal handling and physiological monitoring system. Use this system to secure the subject animal, support the manipulation of the animal during imaging, ensure the comfort of the animal during the imaging session, and monitor the animal’s blood pressure, ECG, temperature and heart rate. Integrated rail base. Provides the stable rail for attaching, sliding and securing the animal platform system, injection system and transducer mounting system.
Section 3 Managing operator access The Vevo 2100 Imaging System provides tools for administrating your operators' access to the system. This section shows you how to use these tools. In This Section Working with operator profiles...........................................................................................61 60 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 9: Working with operator profiles Chapter 9 Working with operator profiles An operator is any person who works with the image data on the system. An operator profile is the access and privilege settings that apply to an operator. This chapter shows you how to set up an access and privilege profile for each person who can operate the system. In this chapter Responsibilities for administrators, owners and operators .............................................61 Adding an administrator..............
Chapter 9: Working with operator profiles User role Description Administrator An administrator is an operator with additional privileges.
Chapter 9: Working with operator profiles 2. Click the Operator tab and then click Add. 3. In the Operator Properties dialog box: a. In the Name box, type a name for the operator. Typically this is the user's personal name. Notes: You cannot type the same name for two operators. Also, you cannot modify the name after you have added the operator, so make sure you type the correct name. b. In the Type choice, select Administrator. c. Select the Password Protected check box.
Chapter 9: Working with operator profiles a. In the Name box, type a name for the operator. Typically this is the user's personal name. Notes: You cannot type the same name for two operators. Also, you cannot modify the name after you have added the operator, so make sure you type the correct name. b. In the Type choice, select Standard. c. If you want to give this operator password protection to prevent nonadministrators from deleting their studies, select the Password Protected check box.
Chapter 9: Working with operator profiles f A standard operator can only change their own password. To modify an operator profile: Prefs 1. Press and then click the Operator tab. 2. In the list of operators, select the operator you want to modify and click Modify. The Operator Properties dialog box appears. 3. Modify the properties and click OK. The system stores your modifications and returns you to the Preferences window. 4. Click OK.
Chapter 9: Working with operator profiles CAUTION: If you do not create at least one Administrator operator as part of your operator group, any operator can add or delete other operators' studies. Important conditions f You can modify your own password Only an administrator can modify the password of another operator To add a password to an operator: Prefs 1. Press and then click the Operator tab. 2. Select the name of the operator and then click Modify. 3.
Chapter 9: Working with operator profiles The system stores the password and returns you to the Operator list. Related information Locking a study (page 131) How passwords and study locks work (page 130) Changing the active operator The active operator is the operator who is listed: In the operator box located above the list of studies in the Study Browser.
Chapter 9: Working with operator profiles Sorting the list of operators f 68 To sort the list of operators: Prefs 1. Press and then click the Operator tab. 2. Click the column heading of the column you want to sort the entries by. For the Name column, the system sorts the entries in alphabetical order. Click the heading to switch the sort order from ascending to descending. For the Type column, the system sorts the entries by type.
Section 4 Setting the operating preferences The Preferences window provides a series of tabs you can use to customize the way you work with the Vevo 2100 Imaging System. In This Section Setting the General tab preferences ....................................................................................70 Setting the Operator tab preferences ..................................................................................79 Setting the Measurement tab preferences ........................................
Chapter 10: Setting the General tab preferences Chapter 10 Setting the General tab preferences Use the General preferences tab to customize a range of frequently used features. In this chapter General preferences ..............................................................................................................70 Cine Loop Size preferences ..................................................................................................71 Auto SAVE preferences ..................................
Chapter 10: Setting the General tab preferences Cine Loop Size preferences Use the Cine Loop Size section to specify the amount of continuous image data you want the system to keep in memory when you acquire a cine loop. Cine Loop Size section displaying the default cine loop size values for each Mode that supports cine loops While you acquire data, the system's playback memory holds your most recent image data in a buffer. The size of the buffer is determined by the Cine Loop Size preference you specify.
Chapter 10: Setting the General tab preferences Auto SAVE preferences Use the Auto SAVE feature when you want to save a cine loop or an image frame without using the Cine Store or Frame Store controls. f To set the system to automatically save an image when you label an acquired image: 1. From the Study Browser (page 49) click Prefs and then click the General tab. 2. In the Auto SAVE section, set your preference settings as described in the following table. 3.
Chapter 10: Setting the General tab preferences 2. In the Auto SAVE On Scan Completion section, select the check boxes for the applicable imaging modes. 3. Click OK. Mode Screen Layout preferences Use the Mode Screen Layout preference to change the relative size of the B-Mode scout window to the mode data window when you are in the following dual window modes: M-Mode, PW Doppler Mode and Tissue Doppler Mode. f To set the Mode Screen Layout preferences: 1.
Chapter 10: Setting the General tab preferences 3. Select Velocity to set the scale to measure the data in mm/s Select Frequency to set the scale to measure the data in kHz Click OK. The system applies the selected scale on the Y axis. PW Doppler Y axis scale set to Velocity Contrast Mode preferences Use the Contrast Mode section to set the default parameters for a pre-triggered destruction burst event for an injected contrast agent. f To set the default burst event parameters: 1.
Chapter 10: Setting the General tab preferences 3. Preference Description Sequence Destroy Position From the drop-down list select the moment in the pre-triggered cine loop when the system begins the destruction burst. The value is set as a percentage. For example, if your cine loop is set to 200 frames and you set the value to 25%, the system will run the destroy burst at frame 50. Click OK.
Chapter 10: Setting the General tab preferences For example, as illustrated below, if you select the Respiration check box but clear the Blood Pressure and Temperature check boxes, you will only see the Respiration display control check box. (Note: The ECG signal input cannot be disabled, so you will always be able to control whether or not to display it.) f To enable or disable a physiological data input: 1. From the Study Browser (page 49) click Prefs and then click the General tab. 2.
Chapter 10: Setting the General tab preferences 3. Preference Description View Blood Pressure Displays the red numeric blood pressure value View Temperature Displays the blue numeric temperature value Click OK. The live data monitor panel displays the real time vital signs of the animal based on the preferences you selected.
Chapter 10: Setting the General tab preferences Related information 78 Physiological Enable preferences (page 75) Physiological Live Display preferences (page 76) VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 11: Setting the Operator tab preferences Chapter 11 Setting the Operator tab preferences The Operator tab is the workspace you use to create and manage the operator profiles for the people who use the Vevo 2100 Imaging System. Administrating your operators (page 60) provides complete instructions on how to work with operator profiles. Related information Rev 1.
Chapter 12: Setting the Measurement tab preferences Chapter 12 Setting the Measurement tab preferences A measurement package is a set of protocol measurements that are related to a specific application. This makes it easier and faster to apply measurements to an image.
Chapter 12: Setting the Measurement tab preferences 2. In the Measurement Package section select a measurement package that closely relates to the type of analysis you routinely perform for the respective imaging. 3. Click Save As, type a name for your new package in the New Measurement Package box and then click OK. 4. Beside the Measurement Package section: 5.
Chapter 12: Setting the Measurement tab preferences 5. f Click Save. To delete a custom measurement package: 1. In the Measurement Package drop-down list select the package you want to delete. 2. Click Delete and then click OK. Exporting and importing custom measurement packages You can export or import custom measurement packages. However, you cannot export or import the default measurement packages that are included with the system. f f To export a custom measurement package: 1.
Chapter 12: Setting the Measurement tab preferences Activating measurement packages f f f To activate a measurement package when you create a new study or series: New 1. Press and then click New Study or New Series. 2. Complete the required fields including the Measurement Package field and then click OK. To activate a measurement package from a mode window: 1. Open an existing image from the Study Browser or start imaging. 2. Press 3.
Chapter 12: Setting the Measurement tab preferences Measurement Parameters preferences Use the Measurement Parameters section to select the measurement parameters that you want the system to display when you add a measurement to an image for a specific measurement package. You can customize the measurements and measurement parameters for custom measurement packages. You cannot customize the measurements and measurement parameters for the default measurement packages that are included with the system.
Chapter 12: Setting the Measurement tab preferences In the Mode window, on the Measured Values section in the measurements panel the system lists only the selected measurement parameters Related information Modifying the properties of a measurement (page 170) Measurement Display preferences Use the Measurement Display preference section to customize how you want your measurements to appear on the images you create for a specific measurement package.
Chapter 12: Setting the Measurement tab preferences Preference Description Show Values and Labels on Image When you select the check box... When you apply a protocol measurement in the image area, the system displays the name of the protocol measurement and all the the parameter values that you specified in the Measurement Parameters preferences section. When you clear the check box...
Chapter 12: Setting the Measurement tab preferences To modify the properties of an existing measurement, right-click the measurement, select Properties, then complete your changes in the Measurement Properties box. Related information Rev 1.
Chapter 13: Setting the Annotation tab preferences Chapter 13 Setting the Annotation tab preferences An annotation is a text label that you add directly to an acquired image. Use the Annotations preferences tab to customize the content and style of the available annotations for a specific application package. In this chapter Measurement Package preferences.....................................................................................88 Annotation Display preferences..................................
Chapter 13: Setting the Annotation tab preferences Preference Description Show Annotations When you select the check box... You can press Update and select or create an annotation. When you clear the check box... The system: Hides any annotations that have already been made Cannot make any annotations IMPORTANT: You must select this check box to add annotations to your image data. Line Style 4.
Chapter 13: Setting the Annotation tab preferences Command Description Add Annotation Adds an item at the bottom of the second-level list under the selected top level item. Note: You cannot create a third level list by adding a sub item to a selected sub item. Edit label Selects the text of the selected item in the list. To rename the item, type the new name and press ENTER . Delete Deletes the selected item. CAUTION: When you delete a top-level item the system also deletes all the sub-items. 4.
Chapter 14: Setting the Presets tab preferences Chapter 14 Setting the Presets tab preferences Use the Presets preferences tab to change a default transducer application or to change a default Mode preset. In this chapter Transducer preferences ........................................................................................................91 Applications preferences......................................................................................................
Chapter 14: Setting the Presets tab preferences TIP: Be sure to click the round button, not the row listing. If you click the row listing, you only display the Mode preset parameters for that application, you do not actually activate the application. You must click the button beside the row to activate it as the default. 4. Click OK. This application remains active until you either disconnect the transducer or return to the Presets tab and activate a different application.
Chapter 14: Setting the Presets tab preferences a. In the Copy From drop-down, select an existing application that contains the Mode presets that are similar to what you want to create. b. In the Name box type the name of the custom application. c. Click OK. The new application appears in the Applications list in the Presets tab.
Chapter 14: Setting the Presets tab preferences The system adds a new folder inside the selected folder in the folder browser window. c. 7. Select the new folder. Click OK. The system exports the application as an AXML file along with a folder that contains the PXML files for all the Mode settings presets that are associated with the application. Importing a transducer application f To import a transducer application: 1. From the Study Browser (page 49) click Prefs and then click the Presets tab. 2.
Chapter 14: Setting the Presets tab preferences 3. In the Applications list click the name of the application you want to delete. 4. Click Delete and click Yes at the confirmation prompt. Mode Settings Presets preferences A mode preset is the group of control panel control levels that are optimized for a specific imaging task.
Chapter 14: Setting the Presets tab preferences Create a new series (page 132) Connect a new transducer Related information Selecting a preset during image acquisition (page 107) Creating a custom Mode settings preset (page 107) Modifying a custom Mode settings preset (page 108) Deleting a mode settings preset You can delete any preset in any custom application, but you cannot delete a default preset. f To delete a mode settings preset: 1.
Chapter 15: Setting the Maintenance tab preferences Chapter 15 Setting the Maintenance tab preferences Use the Maintenance preferences tab to manage system level features. In this chapter Monitor preferences..............................................................................................................97 Systems Log preferences ......................................................................................................97 Upgrade preferences..........................................
Chapter 15: Setting the Maintenance tab preferences Upgrade preferences When VisualSonics issues a software upgrade, the Company sends you a CDROM disk that includes the software upgrade files. Use the Upgrade section to launch the procedure to install the upgrade on your Vevo 2100 Imaging System or Vevo 2100 Workstation. f To install a software upgrade: 1. Insert the Vevo® 2100 System Upgrade Version CD-ROM disk into the DVD drive on the left side of the system. 2.
Chapter 15: Setting the Maintenance tab preferences The Upgrade prompt appears. 6. 7. Rev 1.1 In the Upgrade box: If you are not sure that you have saved your work, click No to cancel the install, save your work and then run the installation process again. If you know that all your work is saved, click Yes to continue the install. The system installs the upgrade and then restarts.
Section 5 Acquiring image data This section walks you through all the steps you need to take so you can start an image acquisition session. WARNING: The Vevo 2100 is not to be used on any living human being. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In This Section Setting up your Vevo 2100 Imaging System ....................................................................101 Setting up Mode settings presets ..........
Chapter 16: Setting up your Vevo 2100 Imaging System Chapter 16 Setting up your Vevo 2100 Imaging System This chapter walks you through the steps for setting up your Vevo 2100 Imaging System and your subject for an image acquisition session. In this chapter Working with transducers .................................................................................................101 Working with the 3D motor stage (optional)...................................................................
Chapter 16: Setting up your Vevo 2100 Imaging System Storing the transducer You can store the transducer in the transducer and gel holder attached to the side of the Vevo 2100 Imaging System, nose upward and with the cable directed toward the front of the cart. Use the spring-loaded cable holder to ensure that the cable does not get twisted. When you move the transducer from one facility to another, always use the dedicated case that is provided with the cart.
Chapter 16: Setting up your Vevo 2100 Imaging System f To connect the 3D motor stage to the Vevo Imaging Station: 1. Insert the quick release post into the quick release mount located on the Imaging Station arm. Quick release post Quick release mount 2. Carefully line up the holes on the post with the pins on the quick release mount. 3. Finger tighten the knob on the quick release mount. 4. Connect the 3D motor cable to the 3D Motor connector on the rear panel of the Vevo 2100 Imaging System.
Chapter 16: Setting up your Vevo 2100 Imaging System 3D motor stage Transducer clamp Transducer 3. Lift the latch to open the clamp and then place the collar of the transducer in the clamp. Latch Moving arm Set screw 104 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 16: Setting up your Vevo 2100 Imaging System Rev 1.1 4. Close the moving arm of the clamp and then pull the latch down to the 45º notch. This transducer rotation lock setting holds the transducer but provides enough freedom for your to rotate it. 5. To set the transducer to any of the at the desired 90-degree angle in the clamp turn the transducer until you feel the collar snap into position. 6.
Chapter 16: Setting up your Vevo 2100 Imaging System Connecting the transducer to the Vevo 2100 Imaging System WARNING: Before connecting or disconnecting any transducer the Vevo 2100 Imaging System must be switched off or the transducer cable disconnected from the rear panel to avoid physical contact with hazardous acoustic transmissions. f To connect the transducer connector to the transducer port: 1. Turn the lock handle to the horizontal (unlocked) position. 2.
Chapter 17: Setting up Mode settings presets Chapter 17 Setting up Mode settings presets If you often use a particular imaging Mode in a similar way, you can optimize your acquisition settings on the control panel and then save them as a single preset. This chapter shows you how to use and manage these presets. In this chapter Selecting a preset during image acquisition ....................................................................107 Creating a custom Mode settings preset ..........................
Chapter 17: Setting up Mode settings presets IMPORTANT REMINDER: When you create a custom preset, it only applies to that specific mode in that specific application for that specific transducer. f To create a custom Mode settings preset: 1. Begin acquiring image data in the imaging mode for which you want to create a preset. 2. Use the control panel controls to optimize your image. 3. Press 4. In the Save Preset Settings box type the name of your preset and click OK. Save Preset .
Chapter 18: Setting up to acquire physiological data Chapter 18 Setting up to acquire physiological data The Advanced Physiological Monitoring Unit tracks your animal's heart rate, temperature, respiration rate and blood pressure (optional with a third-party blood pressure device). NOTE: The system is only compatible with the THM-150 Advanced Physiological Monitoring Unit. The THM-100 is not supported.
Chapter 18: Setting up to acquire physiological data Related information For detailed information on preparing your animal and the animal platform, refer to your Vevo Imaging Station Operator Manual.
Chapter 18: Setting up to acquire physiological data Physiological Display section Use the Physiological Display section in the left panel to activate or deactivate the display controls for the individual physiological data inputs. The selections you make in this section apply both when you are acquiring image data and when you are reviewing it. f To activate or deactivate the display controls for the individual physiological inputs: 1.
Chapter 18: Setting up to acquire physiological data Preference Check box selected Check box cleared BP Derivative Displays the purple blood pressure derivative trace line. This data displays the velocity of change in the BP value. Hides the trace line and data. Dims the waveform slider control. During imaging, activates the blood pressure derivative waveform slider control. Temp 4. Displays the Temp trace line (and numerical data values when you stop imaging) in the physiological trace window.
Chapter 18: Setting up to acquire physiological data f To increase or decrease the amplitude of the waveform: 1. Begin acquiring data in an imaging mode. 2. Press Physio Settings . The left panel displays the physiological display setting sections. 3. In the Physiological Range section: To make the waveform for the selected trace smaller, increase the range value in the slider. To make the waveform for the selected trace larger, decrease the range value.
Chapter 18: Setting up to acquire physiological data Auto-calibrating your Vevo-supported blood pressure instrument The Vevo 2100 Imaging System includes pre-configured calibration settings for the Millar PCU-2000 Pressure Control f To calibrate a Vevo-supported blood pressure instrument: 1.
Chapter 18: Setting up to acquire physiological data The left panel displays the physiological display setting sections. 4. Adjust the blood pressure monitoring system so that the output is 0 mmHg. 5. In the Blood Pressure section: a. In the upper drop-down list select Manual Calibration. b. Click Calibrate. The blood pressure trace (red) should move to coincide with the 0 mark on the blood pressure scale. 6.
Chapter 18: Setting up to acquire physiological data gate period is called the window and is defined by a dark yellow background that follows the trace across the screen. Delay Respiration trace (yellow) Window Before you begin: Your animal must be connected to the Advanced Physiological Monitoring Unit.
Chapter 18: Setting up to acquire physiological data The left panel displays the physiological display setting sections. 3. In the Physiological Range section, adjust the Respiration slider so that the trace line is a) short enough that the peaks and valleys do not extend above or below the window and b) tall enough that you can clearly define those peaks and valleys. 4. In the Respiration Gating section: a. Select the Respiration Gating check box to activate the slider controls. b.
Chapter 18: Setting up to acquire physiological data How ECG triggering works ECG triggering acquires one single frame of image data during each cardiac cycle, at precisely the same time point after the R wave peak, as shown in the following illustration. Before you begin Your animal must be connected to the Advanced Physiological Monitoring Unit. IMPORTANT: You can only activate and control ECG triggering while you are acquiring data. You cannot access these options when you review an image.
Chapter 18: Setting up to acquire physiological data a. In the T1 row select the check box to activate the time slider control as well as the Cycles slider control at the bottom of the section. b. Watch the B-Mode image as you adjust the slider until you find the image within the cardiac cycle that displays the tissue characteristics that you want to study (typically systole or diastole).
Chapter 19: Acquiring image data Chapter 19 Acquiring image data This chapter shows you how to start acquiring micro-ultrasound image data. Before you begin f Ensure that you have connected a transducer to the transducer port on the front of the cart. Ensure that the animal is properly prepared on the animal platform and ensure that the animal is connected to the physiological data support system. To acquire a micro-ultrasound image: 1.
Chapter 19: Acquiring image data 2. On the control panel, press the key for the new imaging mode. For M-Mode press M-Mode a second time to display the M-Mode image in the lower image panel and the B-Mode scout image in the upper image panel. The Mode window displays the image data in the new imaging Mode. Next steps Saving your image data (page 122) Analyzing image data (page 156) Managing your studies (page 125) Related information Rev 1.
Chapter 20: Saving image data Chapter 20 Saving image data You can save your image data in one of two ways: Save your data as a multiple frame animation of your image frames. This ultrasound image is called a cine loop. Save your data as a single frame ultrasound image called an image frame. In this chapter Saving a cine loop (multiple-frame animation)...............................................................122 Saving an image frame ...........................................................
Chapter 20: Saving image data Cine Store 2. Review the image as required and then press . 3. Your Mode window dims and the system pauses the image acquisition. During this image acquisition pause: 4.
Chapter 20: Saving image data When you save your image as an image frame, the system saves the frame that is currently displayed in the Mode window. f To save your image as an image frame: Scan/Freeze Press 2. Turn the Cine Loop Review dial forward and back until you see the frame you want to store. 3. Press 4. Your Mode window pauses for a moment. During this pause: 5. and then Cine Store 1. to create a cine loop. Frame Store .
Section 6 Managing images, series and studies Studies in the Vevo 2100 Imaging System are like studies in a paper based system. They work much like a file directory and hold all the series of images that are part of your study. Studies are composed of one or more grouped image sets called series, and the series are composed of one or more images (individual frames and/or multipleframe cine loops). When you acquire and save an image, the Vevo 2100 Imaging System lists the image in the Study Browser.
Chapter 21: About studies, series and images Chapter 21 About studies, series and images The Study Browser organizes your work into studies, series and images and displays them in the following hierarchy: Study Series Image The following illustration and table describes how the hierarchy of Study / Series / Image works and how it appears in the software. Study Browser window featuring the study, series and images of a selected study Area Description Study.
Chapter 22: Working with studies Chapter 22 Working with studies Studies are the largest grouping you can work with in the Study Browser. Studies contain your images. And these images are grouped into series which list all the images you create during an acquisition session. You can organize your studies any way you want, based on the type of study you are working on. Sometimes you will create a study that tracks a specific set of images of one animal over a period of time.
Chapter 22: Working with studies The mode window appears and displays the system-generated study name and series name. You have successfully created a study. 3. Store images to your series and then close the series. BE CAREFUL: If you don't store images to the first and only series of a study, the system removes both the series as well as the study when you close the series. The Study Information window appears. 4. Complete the required fields and any optional fields as needed and click OK.
Chapter 22: Working with studies Finding a study When your list of studies is long and you need to find a specific study, use the Study Browser sorting features. f To find a study: 1. Press Study Management . The Study Browser appears. 2. 3. Click a column heading to sort the list of studies. Click Name heading to display the list in alphanumeric order based on the name of the study. Click the heading again to switch the sort order of the column between ascending order and descending order.
Chapter 22: Working with studies 4. Box Description Owner Read-only Study Name Required. Type your information. Granting Institution Optional. Type your information. Study Notes Optional. Type your information. Click OK. The Study Browser returns. Related information Study Browser window workspace (page 49) Study Information window workspace (page 50) How passwords and study locks work You can review any images in any study on your Vevo 2100 Imaging System at any time.
Chapter 22: Working with studies Locking a study Any operator can lock any study. When you lock a study, all the operators on the system can still review and manage the images in the study. Before you can delete a study or series or image within a study, unlock the study. f f To lock a study: 1. In the Study Browser, in the lock column that you want to lock. select the check box for the study 2. The system adds a check mark in the lock column. To delete a locked study: 1.
Chapter 23: Working with series Chapter 23 Working with series Series are sub-groupings within studies that list all the images you create during acquisition. Use series to create useful image groupings within your study. Whenever you create a new study, in the Study Browser the system automatically creates the first series. Typical uses for series Let's say your study tracks a specific set of images of one animal over a period of time.
Chapter 23: Working with series The system creates the new study and automatically creates the first series in the study. f To add a new series to an existing study: 1. In the Study Browser, select the study that will contain the new series. 2. Press New . The system prompts you to create either a new study or a new series. 3. Click New Series. The New Series window appears. 4. In the Series Information section, modify the series parameters as required. 5. Click OK.
Chapter 23: Working with series Box Description Series Name Required. Acquired By Required. Date of Birth Optional. Click the calendar icon and select the date that the animal was born. Sex When you select Female, the system displays the Pregnant option. Pregnant Optional. Select the check box. The system displays an optional Date Mated calendar field. If you want to add that data, click the calendar icon and select the date.
Chapter 23: Working with series Deleting a series You can delete a series from any unlocked study. f To delete a series: 1. 2. In the Study Browser, select the series you want to delete: Click to select one series CTRL +click Click+ Press DEL to select a collection of individual series SHIFT +click to select a range of series or click Delete in the Study Browser. The Delete Confirmation window appears.
Chapter 24: Working with image items in a study series Chapter 24 Working with image items in a study series Images are saved cine loops and image frames that are listed in a series within a study. In this chapter Opening an image ...............................................................................................................136 Labeling an image ...............................................................................................................136 Storing an image...............
Chapter 24: Working with image items in a study series a. AutoSAVE on Image Label is selected in the General tab of the Preferences window -orb. The image has not been saved previously f To label an image from the Study Browser: Method A (Vevo 2100 Imaging System control panel): 1. 2. Expand the study and series and select the image you want to label. In the list of studies, select the image row. In the thumbnails panel, scroll to view the image and select the image. Press Image Label .
Chapter 24: Working with image items in a study series The system saves the cine loop frames as a single image item and lists the image in the Study Browser. f To store a single-frame image: You can use Frame Store to a single-frame image in B-Mode, Color Doppler Mode, Power Doppler Mode and Contrast Mode. For M-Mode, PW Doppler Mode and PW Tissue Doppler Mode, this key stores the complete cine loop. 1. Begin acquiring data in an imaging Mode, or review a stored cine loop from the Study Browser. 2.
Chapter 25: Exporting studies, series or images Chapter 25 Exporting studies, series or images The Export function: a. Translates your images from the proprietary Vevo 2100 Imaging System file format into industry formats you can work with on another computer. b. Transfers the translated files to a network location or an external storage device that you connect to the USB ports or the Firewire port on the rear panel of the Vevo 2100 Imaging System.
Chapter 25: Exporting studies, series or images Important tip: When you select a series or a study that includes image frames as well as cine loops, the system only exports the selected cine loop images. You do not have to de-select the image frames. You can just select the series row or even the whole study and the system will export only the cine loops. 3.
Chapter 25: Exporting studies, series or images c. 8. In the Quality row, click High or Medium based on your requirements. Quality Description Medium Slightly lower resolution High Highest resolution Click OK. The system exports the images to the folder you selected and then presents the Image Export Report. 9. Click OK. The system returns you to the Study Browser.
Chapter 25: Exporting studies, series or images Exporting image frames from the Study Browser Before you begin Ensure that the Vevo 2100 Imaging System is connected through the appropriate ports on the rear panel of the system to a data storage location on your network or to an external storage device. f To export image frames from the Study Browser: 1. Press Study Management . The Study Browser appears. 2. Select the image frames you want to export.
Chapter 25: Exporting studies, series or images a. In the top box: If you are exporting a single image, the system labels this box Save As. You can keep the system defined date and time stamp file name or type a new file name. If you selected to export multiple images, the system labels this box File Name Prefix. Type in text that will be added to the start of all the individual image files that you have selected to export.
Chapter 25: Exporting studies, series or images Same image exported as image area BMP c. 8. If the system detects that the file names of any images you selected for export are identical to any file names in your export folder, the system prompts you to choose how to proceed: Click Yes to overwrite the files Click No to return to the Export Image window Click OK. The system exports the images to the folder you selected and then presents the Image Export Report. 9. Click OK.
Chapter 25: Exporting studies, series or images Exporting an image frame from the Mode window If you are analyzing an image frame in the Mode window, you don't have to return to the Study Browser to export it. You can export it directly from the Mode window. Before you begin Ensure that the Vevo 2100 Imaging System is connected through the appropriate ports on the rear panel of the system to a data storage location on your network or to an external storage device.
Chapter 25: Exporting studies, series or images 3. If you want to export multiple single cine loop images or image frame images or a combination of both image types, expand and select the study rows or series rows that contain the images you want to export. Press Select Press CTRL + Select Press Select Press Export to select one row + to select a collection of individual rows SHIFT +scroll+ Select to select a range of rows . The Export Image window appears. 4.
Chapter 25: Exporting studies, series or images c. If your DICOM system supports regions: Select the Export regions check box to export the file with separate calibration data for the main image area as well as the B-Mode scout window. Clear the Export regions check box to export the file with only the calibration data for the main image area. d.
Chapter 25: Exporting studies, series or images The Export Images window appears. 2. Complete the export procedure as detailed in Exporting to DICOM from the Study Browser (page 145). Exporting the Study Browser list view as a text file The Study Browser list view is the exact representation of what appears in your Study Browser when you scroll from the top to the bottom.
Chapter 25: Exporting studies, series or images The Export Image window appears. 4. In the folder browser, browse to the location where you want to export your data and select the folder. 5. If you need to create a new folder: a. Click New Folder. b. Type the name of the new folder and click OK. The system adds a new folder inside the selected folder. 6. In the Export Type section click Table. 7. (Optional) In the Options section type a unique name to replace the default time stamp. 8. Click OK.
Chapter 25: Exporting studies, series or images For example if your Study Browser includes 50 studies and you expand only the sixth study and its series and images, your export will include all the listing information for the one study that you expanded completely, and include only the study rows for the other 49 studies.
Chapter 25: Exporting studies, series or images The system exports the Study Browser window contents as a TXT file to the location you specified. Rev 1.
Chapter 26: Copying, deleting and importing Chapter 26 Copying, deleting and importing The Vevo 2100 Imaging System provides a range of features for copying, deleting and importing study data. In this chapter Copying studies, series or images.....................................................................................152 Deleting studies, series or images .....................................................................................153 Importing studies .....................................
Chapter 26: Copying, deleting and importing The system adds a new folder inside the selected folder in the folder browser window. 5. In the Options section, in the Save As box, if you want to change the name of the study, type the new name. 6. Click OK. The system: a. Copies the studies to the folder you selected. b. Displays the Copy Study Report box to summarize the details of the copy process. Click OK to complete the process. c. Returns you to the Study Browser.
Chapter 26: Copying, deleting and importing Note: If one or more of the studies are locked, the system will not delete them. b. Displays the Delete Confirmation box to summarize the details of the deletion process. 3. Click Yes. The system returns to the Study Browser. Importing studies Use this command to copy studies acquired on another Vevo 2100 Imaging System or from another storage location.
Chapter 26: Copying, deleting and importing 4. If you want to remove a study from the Selected Studies list, select the study and then click Remove. 5. Click OK. The system: a. Imports the studies that you selected. b. Displays the Copy Study Report box to summarize the details of the import process. Click OK to complete the process. c. Rev 1.1 Returns you to your previous workspace.
Section 7 Analyzing image data This section walks you through the typical tasks you will complete when you are analyzing your images. In This Section Vevo Imaging Workstation................................................................................................157 Working with cine loops ....................................................................................................158 Measurement basics...........................................................................................
Chapter 27: Vevo Imaging Workstation Chapter 27 Vevo Imaging Workstation VisualSonics offers an optional Vevo 2100 Workstation Software package which includes all the software tools and features that you will find on the Vevo 2100 Imaging System excluding the image acquisition tools features. Rev 1.
Chapter 28: Working with cine loops Chapter 28 Working with cine loops A cine loop is the trailing series of acquired images that the system holds in its memory buffer as you acquire image data. In B-Mode, the cine loop is a set of frames. In PW Doppler Mode and M-Mode, the cine loop is the data acquired over a time interval. In this chapter Cine loop workspace...........................................................................................................158 Cine loop review controls ...
Chapter 28: Working with cine loops Area Description Frame counter. Indicates the location of the current frame. The counter indicates the frame number and the total number of frames located within the buffer. To view another frame in the cine loop, click on the triangular frame indicator and drag it to the desired frame. Range start frame number. Range start bracket. Defines the start of the cine loop range you want to review. You can create a range within the full cine loop.
Chapter 28: Working with cine loops Reviewing a cine loop on the Vevo 2100 Imaging System When you are playing a cine loop on the Vevo 2100 Imaging System these are the controls you use. Cine Loop Review Controls all cine loop review functions.
Chapter 28: Working with cine loops Scan/Freeze During image acquisition, toggles between acquiring image data and freezing the acquisition. When you freeze the acquisition the system stores cine loop data if you select Auto SAVE on Image Label in the General tab of the Preferences window. During image analysis, starts and stops data playback. Trackball.
Chapter 28: Working with cine loops Press Cine Store after you have acquired your image or at any time while you are acquiring image data. This stores the buffered cine loop frames as an image that appears in your Study Browser. Pause an acquired cine loop, drag the left or right cine loop range bracket to isolate a range of image frames within the original cine loop and then press Cine Store to store the range of image frames as a cine loop.
Chapter 28: Working with cine loops Area Description Physiological trace graph Current frame data values Before you begin Ensure that you select the desired physiological inputs in the Physiological Enable section of the General tab in the Preferences window. f To show or hide individual traces in the graph: Physio Settings 1. Press . 2.
Chapter 29: Measurement basics Chapter 29 Measurement basics This chapter describes where to find the measurement tools, and the the types of measurements you can add to an image. In this chapter Measurement panel workspace.........................................................................................164 Generic measurements .......................................................................................................166 Complete procedure for adding a generic measurement ..............
Chapter 29: Measurement basics The measurement panel appears on the left side of the window. Measurement panel workspace The following illustration and table describes the information and features in the measurement panel. Area Description Generic measurement tools. Each imaging Mode provides a unique set of tools. Click the tool and then apply the measurement on the ultrasound imaging area. Measurement package.
Chapter 29: Measurement basics Area Description Protocol measurement item. A measurement for a specific protocol. Each protocol measurement uses one of the generic measurement tools that are displayed for the active imaging Mode. Click the measurement item and then apply the measurement on the ultrasound imaging area. Measurement values list. Displays the measurements that have been applied to the image.
Chapter 29: Measurement basics 2. Click the measurement button you want to use. If you are not sure which button you need, hover your cursor over the button to view the pop-up button label. For example, for a linear distance measurement, click selected until the measurement is completed. . The button remains While you apply the measurement, you can look in the measured values list area at the bottom of the left panel to see a magnified view of your cursor area. 3. Click to apply your caliper points.
Chapter 29: Measurement basics Adding protocol measurements Protocol measurements are labeled uniquely for a specific measurement protocol. f f 168 To access the protocol measurement tools and measurements list Scan/Freeze If you are in an image acquisition session press image and then press Measure . to acquire an If you are in the Study Browser, open an image and then press Measure . To place a protocol measurement: 1.
Chapter 29: Measurement basics The system automatically activates the appropriate measurement tool and highlights the generic button for that tool. 4. On the image, add your measurement. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement.
Chapter 30: Working with measurements Chapter 30 Working with measurements This chapter shows you how to complete measurement tasks that are used for many measurements in many imaging Modes. In this chapter Modifying the properties of a measurement ...................................................................170 Modifying points on a contour measurement .................................................................171 Modifying contour measurements.................................................
Chapter 30: Working with measurements The Measurement Properties box appears. 2. Modify the properties as required and click OK. Related information Measurement Display Options preferences (page 85) Measurement Parameters preferences (page 84) Modifying points on a contour measurement f Rev 1.
Chapter 30: Working with measurements Modifying contour measurements f To modify a contour: To move the contour (all the caliper points as a group) click the center point of the trace, trackball to the new position, then click again to commit the contour. To resize the contour, click the contour, trackball the cursor inward or outward to change the size, then click to commit the resized contour. To delete the contour, right-click the curve and select Delete.
Chapter 30: Working with measurements 8. In the protocols list select the protocol measurement you want to work with and then add the measurement on the image.
Chapter 30: Working with measurements This bottom point of the first measurement automatically becomes the top point of the second measurement in the chain, for example, the IVS;d measurement. 5. Click the bottom point of the second measurement. The system measures and labels the second measurement and stores the image. 6. Click the remaining bottom points of the next measurements in the chain. The system measures and labels each measurement until the final measurement is completed.
Chapter 31: Working with annotations Chapter 31 Working with annotations Annotations are text labels that you can add to any ultrasound image. When you store an image or cine loop, the system includes any annotations as part of the image or cine loop. Note: The system does not include annotations when you export M-Mode, PW Doppler Mode, or PW Tissue Doppler Mode images. However, if the annotations are in the BMode scout window, they are exported.
Chapter 31: Working with annotations Area Description Predefined annotation. A default or custom annotation. To add a predefined annotation right-click on the image > select a package category > select an annotation. Anchor line. Appears when you drag the annotation text. Visually links the annotation text to the caliper point on the image where you added the annotation. Generic Text annotation - modified. An annotation that you type in manually on the image.
Chapter 31: Working with annotations Category Annotation text Kidney Cortex Medulla Hilum Renal Vein Renal Artery Left Kidney Right Kidney Liver Hepatic Artery Hepatic Vein Portal Vein Lobe Right Lobe Left Lobe Liver Other Abdominal Adrenal Gland Intestines Bladder Reproductive Group Ovary Uterus Uterine Horn Testicle Seminal Vesicle Prostate Physiological Inspiration Expiration Electrical Systole Electrical Diastole Mechanical Systole Mechanical Diastole Max dP/dT Cardiac Package annotations
Chapter 31: Working with annotations Category Cardiology Annotation text Left Ventricle LV PW Right Ventricle RV AW Left Atrium Right Atrium Intra-Ventricular Septum Infarct Respiratory Motion Coronary Artery Aortic Valve Mitral Valve Tricuspid Valve Pulmonary Artery Pulmonary Valve Physiological Inspiration Expiration Electrical Systole Electrical Diastole Mechanical Systole Mechanical Diastole Max dP/dT Embryology Package annotations 178 Category Annotation text Generic text Annotation text V
Chapter 31: Working with annotations Category Embryology Annotation text Placenta Umbilical Cord Embryo Neural Tube Heart Tube Heart Aorta Eye Lens Retina Liver Somite Lungs Lateral Ventricle Third Ventricle Fourth Ventricle Fetal/Maternal Blood Flow Umbilical Vein Umbilical Artery Vitelline Artery Vitelline Vein Placenta Reproductive Ovary Uterus Uterine Horn Testicle Seminal Vesicle Prostate Physiological Inspiration Expiration Electrical Systole Electrical Diastole Mechanical Systole Mechanical
Chapter 31: Working with annotations Category Annotation text Ophthalmology Cornea Iris Lens Sclera Corneo-scleral junction Cataract Normal angle Physiological Inspiration Expiration Electrical Systole Electrical Diastole Mechanical Systole Mechanical Diastole Max dP/dT Vascular Package annotations Category Annotation text Generic Text Annotation text Vascular Group Innominate Artery Right Common Carotid Artery Left Common Carotid Artery Left Subclavian Artery Abdominal Aorta Inferior Vena Cava
Chapter 31: Working with annotations f To add a custom annotation: Method 1 1. Right-click on the ultrasound image. 2. Select Generic Text. The system adds an editable text field. ENTER 3. Type your custom annotation and press . 4. If you want to move the annotation, drag the annotation. The label moves and maintains a line to the initial point where you added the annotation. Method 2 (Vevo 2100 Imaging System) 1. Press Cursor 2. Press Annotate to toggle the cursor off. .
Chapter 31: Working with annotations f To delete an annotation: Right-click the annotation and select Delete. f f To show/hide annotations: 1. From the Study Browser (page 49) click Prefs and then click the Annotations tab. 2. In the Annotations Display section, select or deselect the Show Annotations check box. To modify the properties of an annotation: 1. Right-click the annotation and select Properties. The Annotation Properties box appears. 2. 3.
Chapter 31: Working with annotations f Rev 1.1 To modify the list of predefined annotations: 1. From the Study Browser (page 49) click Prefs and then click the Annotations tab. 2. Add, reorder or delete package categories and category annotations as detailed in Setting the Annotation tab preferences (page 88).
Chapter 32: Reporting your analysis results Chapter 32 Reporting your analysis results This chapter describes how to work with the measurements, calculations and annotations that you add to the image data. In this chapter Creating an analysis report ................................................................................................184 Reviewing the image that contains a report measurement ...........................................185 Exporting an image analysis report .......................
Chapter 32: Reporting your analysis results 3. Press CTRL + Select Press Select + to select a collection of individual rows SHIFT +scroll+ Select to select a range of rows Click Report. The system compiles your selections into a single report. Reviewing the image that contains a report measurement f To review the image that contains a report measurement: 1. In the analysis report, select a measurement row.
Chapter 32: Reporting your analysis results The system exports your analysis report as a CSV file which you can load into third party tools such as spreadsheet software so you can complete additional statistical analysis.
Chapter 32: Reporting your analysis results The system adds a new folder inside the selected folder in the folder browser window. 6. In the Export Type section click Report. 7. (Optional) In the Options section type a unique name to replace the default time stamp. 8. Click OK. The system exports your report to the folder you selected and returns you to the Study Browser. f To export your analysis report from the Analysis Browser: 1.
Chapter 32: Reporting your analysis results 8. The system exports the analysis report for the image you are viewing. Exporting an analysis report You can export measurements and calculations as a CSV file that you can import into a spreadsheet or a database for further analysis. Before you begin Ensure that the Vevo 2100 Imaging System is connected through the appropriate ports on the rear panel of the system to a data storage location on your network or to an external storage device.
Section 8 B-Mode imaging and analysis B-Mode is the imaging mode you will work with most often because it is the most effective mode for locating anatomical structures. If you have seen a conventional ultrasound image then you are already familiar with B-Mode.
Chapter 33: Acquiring B-Mode images Chapter 33 Acquiring B-Mode images This chapter shows you how to acquire B-Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical B-Mode image acquisition session ......................................................................190 B-Mode window workspace ..............................................................................................
Chapter 33: Acquiring B-Mode images The icon indicates the position of the orientation ridge of your transducer in relation to your image. 4. Adjust the Image Width control to remove image content outside the region of interest to optimize the image data for analysis. 5. Press Presets to cycle through the available presets and then select an appropriate set of optimized image acquisition settings. 6.
Chapter 33: Acquiring B-Mode images B-Mode window workspace The B-Mode window is the workspace you use whenever you view image data in B-Mode. The following illustration and table describes the information and features in the B-Mode window. Area Description Image area export zone. When you export a stored image and configure your export to send only the Image Area, this is the area of the window that the system exports, along with header information. Micro-ultrasound image.
Chapter 33: Acquiring B-Mode images Area Description Focal depth indicator. When you acquire data, use the Focal Zones control on the control panel to add up to three focal zones. Transducer orientation indicator. The line in this icon corresponds to the orientation ridge on the transducer and indicates the orientation of the probe relative to the image. Dynamic range bar. Indicates the input signal strength that is mapped into the gray scale of the display.
Chapter 33: Acquiring B-Mode images Control panel controls for B-Mode When you are acquiring B-Mode image data, these are the controls you use to optimize the image you see on the screen. Image Width Adjusts the physical width of the area the transducer is imaging. Push up to increase the width. Pull down to decrease the width. Tip: The closer you can reasonably narrow the width of your image around your target structure, the higher the system sets the acquisition frame rate.
Chapter 33: Acquiring B-Mode images Image Depth Adjusts how deep in mm you want to display the ultrasound signal. Pull down to increase the depth. Push up to decrease the depth. The available depth is transducer dependent. Focus Depth Adjusts the depth of the B-Mode focal zone or focal zones on your image. When you have more than one focal zone this control moves the depth of all the focal zones as a group. Push up to decrease the depth. Pull down to increase.
Chapter 33: Acquiring B-Mode images Presets Active during image acquisition in all modes except 3D-Mode. This rocker switch cycles you through all the preset groups of acquisition parameters for the active imaging Mode. The list of presets include the transducer-specific presets as well as any custom presets that other operators added to the system. All presets are both mode dependent, transducer dependent and application dependent. Transmit Power Adjusts the power of the ultrasound signal transmission.
Chapter 33: Acquiring B-Mode images Persist Applies a pixel averaging algorithm to the most recently acquired frames to produce a more uniform view of the faster moving areas in the image data. To use this rocker switch control: Push up or down to cycle through the persistence levels. In the bottom-left corner of the screen the status bar briefly displays the name of the persistence label as you select. In B-Mode: Reduces distracting artifacting such as shimmering effects. Levels: Off, Low, Med, High.
Chapter 33: Acquiring B-Mode images B-Mode acquisition settings f To view the B-Mode acquisition settings: Press Mode Settings . The B-Mode acquisition settings panel displays the following parameters, in addition to labeling the current transducer application and preset: Transmit Parameter Description Frequency The ultrasound frequency, measured in MHz. Adjust with the Frequency control. Power The transmission power level of the ultrasound signal, displayed as a percentage of the maximum power.
Chapter 33: Acquiring B-Mode images Adding focal zones Focal zones enhance the resolution across your image, while slightly reducing the acquisition frame rate. The system always displays at least one focal zone, and you can apply a maximum of two additional zones depending on the transducer. When you add focal zones the system maximizes the resolution for a larger area of your image, and reduces the acquisition frame rate. f To add a focal zone: 1. 2. Press zone.
Chapter 33: Acquiring B-Mode images 2. With the injection target below focus or out of the plane, using the Vevo 2100 Imaging Station physically extend the needle into the image, toward the expected target location. Bring the needle tip as close to the focal depth as possible. 3. Turn the Screen Keys dial to highlight the Needle Guide Overlay option that is displayed at the bottom left corner of the window. 4. Turn Screen Keys to activate the Needle Guide Overlay feature. 5.
Chapter 33: Acquiring B-Mode images Cine Store 15. To save a cine loop of the injection event, press . 16. Physically retract the needle using the Vevo 2100 Imaging Station. Related information Rev 1.
Chapter 34: Analyzing B-Mode images Chapter 34 Analyzing B-Mode images This chapter shows you how to analyze B-Mode images that are saved to a study. In this chapter Adding generic B-Mode measurements...........................................................................202 Adding protocol measurements........................................................................................208 Creating pressure-volume loop measurements in B-Mode ...........................................
Chapter 34: Analyzing B-Mode images f To place a linear distance measurement: 1. Click the linear distance measurement button . 2. Click on your image to place the initial caliper. 3. Trackball to the location where you want to end your measurement and then click to place the end caliper. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement. 4.
Chapter 34: Analyzing B-Mode images 3. Trackball along the contour of your target tissue and then right-click to place your last caliper. If the position of the trackball cursor is within five pixels of the previous caliper when the right-click occurs, the system sets the previously placed caliper as the last caliper and auto-closes the measurement. This feature applies to 2D area measurements in B-Mode, 3D-Mode, and Contrast Mode as well as for 3D-Mode volume contours. 4.
Chapter 34: Analyzing B-Mode images LV Area long axis measurement Use the LV wall trace measurement to trace the endocardial wall through multiple cardiac cycles, semi-automatically or manually. This is an optional function, and is available only if the Automated LV Analysis package is purchased. f To place an LV area long axis measurement semi-automatically: 1.
Chapter 34: Analyzing B-Mode images In this example, six wall points have been added to the trace curve Right-click the final point on the contour to complete the measurement. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement B-Mode LV Area #, where # is a sequential number. 6.
Chapter 34: Analyzing B-Mode images Modifying points on an LV area trace f To modify points on a contour: To move a point, drag it to a new position, then click again to commit the point To add a point, click the contour, move the cursor to a new position, then click again to commit the new point To delete a point, right-click the point and select Delete Point Modifying the LV area trace f To modify a contour: To move the contour (all the caliper points as a group) click the center point
Chapter 34: Analyzing B-Mode images 7. If you have selected Show Values and Labels in the Measurement tab of the Preferences window and you want to move the measurement or move the label, select either item and then drag and drop it. 8. Right-click the contour and select Replicate Forward or Replicate Reverse and select the number of cycles. The system automatically traces the wall forward or backward through the frames. 9. Press Cine Store to save the cine loop.
Chapter 34: Analyzing B-Mode images f f To access the protocol measurement tools and measurements list Scan/Freeze If you are in an image acquisition session press image and then press Measure . to acquire an If you are in the Study Browser, open an image and then press Measure . To place a protocol measurement: 1. In the measurement packages drop-down list click the appropriate package. 2. In the list of protocols, select the appropriate protocol. 3.
Chapter 34: Analyzing B-Mode images Related information Analyzing image data (page 156) Protocol measurements (page 167) Lens radius measurement The lens radius measurement is only available in the Ophthalmology measurement package for B-Mode images. Lens radius is measured in mm. f To place a lens radius measurement: 1. Open an existing eye image or begin acquiring an eye ultrasound image and then press Scan/Freeze . 2. Press 3.
Chapter 34: Analyzing B-Mode images 3. Right-click the measurement and select PV Curve. Note: The PV Curve menu command is not available if the image does not include blood pressure data. 4. The system calculates the pressure-volumes of the cardiac cycles and plots them as a graph on the Pressure Volume Relationship window. Pressure-Volume relationship graphs When you have generated pressure-volume graph data, you can use the tools on the Pressure Volume Relationship window to: Rev 1.
Chapter 34: Analyzing B-Mode images ESPVR check box Check this box to display the end systolic PV points. If the graph displays a single loop, the system plots a green dot on the curve at the End Systolic point. If the graph displays multiple loops, the system plots a best-fit line through the End Systolic points. EDPVR check box Check this box to display the end diastolic points. If the graph displays a single loop, the system plots a red dot on the curve at the End Diastolic point.
Chapter 34: Analyzing B-Mode images When the Average option is selected, the graph displays a single smooth loop. When the Average option is cleared, the graph plots the cardiac cycle. Volume command Click this command to toggle the horizontal dimension between Volume and the basic dimension of the loops. For measurements made in M-Mode the dimension is Diameter in millimeters. For measurements made in B-Mode, the dimension is Area in square millimeters.
Chapter 34: Analyzing B-Mode images The system processes the cine loop and then displays the cine loop in the VevoStrain workspace. 2. In the B-Mode panel (area as shown below): a. Use the playback controls below the B-Mode scout window to display the image frame you want to work with. b. Click above the LV wall, trackball across the chamber to beyond the opposite wall at whatever angle you prefer, and then right-click to set the AM-Mode cross-section. c. 3.
Chapter 34: Analyzing B-Mode images 4. On the AM-Mode image (area ): a. Click on the R wave where for the first cardiac cycle. The system applies a vertical blue line. b. Click on the other R waves to add the remainder of your cardiac cycles. The system applies a second blue line and connects the two lines with a green line. For the best results, create your selection period between one respiration cycle and the next. c. 5.
Chapter 34: Analyzing B-Mode images If you want to delete the trace and start again, delete the old trace from the History and select a new trace. If you want to return to the AM-Mode view to select a new cardiac period, click the Sequence button below, create the new period and then click Next again. 9. Click the Start Analysis button. 10. VevoStrain builds the dynamic LV wall trace for all frames in the cine loop and graphs the results in the analysis workspace.
Chapter 34: Analyzing B-Mode images Strain rate step 2: Analyzing the data Before you begin You must complete the procedure in Strain rate step 1: Adding the LV wall trace (page 213). VevoStrain analysis window workspace The following illustration and table describes the information and features in the VevoStrain analysis window workspace. Area Description LV wall trace on B-Mode cine loop. Features the automatic endocardial wall trace through all frames.
Chapter 34: Analyzing B-Mode images Area Description Graph. Parametric distribution for the radial axis. Graph. Velocity distribution along the longitudinal axis. Graph. Parametric distribution along the longitudinal axis. Analysis tools group. Includes: Row 1 (top row): Time to Peak Analysis, New Trace, Edit Trace. Row 2: Export AVI, Export Picture, Export Data, Sequence/M-Mode Selection.
Chapter 34: Analyzing B-Mode images Image Toggle description Contour Vector Orbit line B-Mode 2. Rev 1.1 To modify the size of the vector use the Decrease Vector Size, Reset Vector Size or Increase Vector size buttons on row three of the analysis tools group.
Chapter 34: Analyzing B-Mode images Displaying individual curves for specific points on the trace in VevoStrain Before you begin You must complete the procedure in Strain rate step 1: Adding the LV wall trace (page 213). By default the system displays all the curves for the individual points along the trace. f 220 To display the curve for a specific point on the trace: 1. Click on the contour to create a point. 2. The graph displays the curve for the individual point. 3.
Chapter 34: Analyzing B-Mode images 4. The system applies unique colors to the additional points on the trace and the corresponding curves on the graph. Analyzing time-to-peak in VevoStrain Before you begin You must complete the procedure in Strain rate step 1: Adding the LV wall trace (page 213). Time-to-peak analysis displays the synchronicity and phase for different segments of the heart. The display for the segments varies depending on the view of the heart: long/short axis or apical.
Chapter 34: Analyzing B-Mode images Time-to-peak window for short axis wall data Features 222 Time-to-peak is calculated as the time from the reference axis, 0.000, to the maximum peak (negative or positive), for each of the segments of the heart in the specific view. Low time-to-peak comes displayed in blue and high in red. The phase measures the synchronicity located between regions of the heart for a selected time interval.
Chapter 34: Analyzing B-Mode images Viewing strain data in 3D in VevoStrain Before you begin f To view strain data in 3D: 1. From the VevoStrain analysis window, click the 3d button that is located to the left of the parametric distribution graph. 2. The system displays the strain rate data in three dimensions. 3. Modify your view of the data. 4. Rev 1.1 You must complete the procedure in Strain rate step 1: Adding the LV wall trace (page 213).
Section 9 M-Mode imaging and analysis M-Mode is used primarily to measure the movement of structures in the heart such as valves, chambers, and walls. In This Section Acquiring M-Mode images ................................................................................................225 Analyzing M-Mode images ...............................................................................................235 224 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 35: Acquiring M-Mode images Chapter 35 Acquiring M-Mode images This chapter shows you how to acquire M-Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical M-Mode image acquisition session.....................................................................225 M-Mode window workspace.............................................................................................
Chapter 35: Acquiring M-Mode images The system begins acquiring B-Mode image data and displays the yellow MMode sample gate overlay on the B-Mode image. 4. Press Update or press M-Mode again. The dual-window M-Mode image area workspace appears. The M-Mode window is on the bottom, the B-Mode scout window is on the top. The system begins storing cine loop data in the acquisition buffer, and live acquisition data appears in both windows. 5.
Chapter 35: Acquiring M-Mode images M-Mode window workspace The M-Mode window is the workspace you use whenever you view image data in M-Mode. The following illustration and table describes the information and features in the M-Mode window. Area Description M-Mode Image area export zone. When you export a stored image and configure your export to send only the Image Area, this is the area of the window that the system exports, along with header information. B-Mode scout window.
Chapter 35: Acquiring M-Mode images Area Description Sample gate overlay in B-Mode scout window. Shows you precisely where the region of interest is. The region of interest is located between the yellow wireframe brackets set. Use this window to reposition your transducer and the wireframe brackets set so you can acquire the most useful data. M-Mode image data. Displays the cardiac cross-section image data acquired along the sample gate line in the B-Mode scout window.
Chapter 35: Acquiring M-Mode images Control panel controls for M-Mode When you are acquiring M-Mode image data, these are the controls you use to optimize the M-Mode image data you see in the lower window of the image area. M-Mode Activates M-Mode image acquisition. To use this key control: 1. Press to begin displaying the M-Mode sample volume overlay on the full-window BMode acquisition data. 2.
Chapter 35: Acquiring M-Mode images Transmit Power Adjusts the power of the ultrasound signal transmission. Turn clockwise to increase power. Turn counterclockwise to decrease power. Between 1% and 10% power the control adjusts power in increments of 1%. Between 10% to 100% power the control adjusts in increments of 10%. Frequency Adjusts the transmit frequency of the transducer between the higher and lower frequency levels that are supported by the specific transducer.
Chapter 35: Acquiring M-Mode images Invert Flips the image. In M-Mode: In the dual window view, press to flip the B-Mode scout image left/right. Display Map Cycles you through a predefined set of optimization maps that you can apply either while you are acquiring or reviewing image data. Push up or pull down to cycle through the available maps for the active imaging mode. Dynamic Range Adjusts the input signal strength that is mapped into the spectral display. Range: 5100dB.
Chapter 35: Acquiring M-Mode images Update Function 1: display control Alternates the display from the dual view (B-Mode scout window on top, Mode image window on the bottom) to the B-Mode image plus overlay so you can position your sample gate more precisely. To use this toggle control: 1. Press to view the dual view. 2. Press again to display the B-Mode window and overlay. Function 2: right-click button When the manual directs you to right-click, press Update . SV/Gate Push up to increase.
Chapter 35: Acquiring M-Mode images M-Mode acquisition settings f To view the M-Mode acquisition settings: Press Mode Settings . The left panel displays the following parameters, in addition to labeling the current transducer application and preset: Transmit Parameter Description Frequency The ultrasound frequency, measured in MHz. Adjust with the Frequency control. Power The transmission power level of the ultrasound signal, displayed as a percentage of the maximum power.
Chapter 35: Acquiring M-Mode images Setting the M-Mode region of interest In M-Mode, the region of interest is the image data that the transducer acquires along the vertical line between the brackets of the yellow wireframe in the BMode image. This line is called the sample gate. f To set your M-Mode sample gate: 1. Begin acquiring data in M-Mode and position your transducer to display your region of interest in the center of the B-Mode scout window. 2.
Chapter 36: Analyzing M-Mode images Chapter 36 Analyzing M-Mode images This chapter shows you how to analyze M-Mode images. In this chapter Adding generic M-Mode measurements .........................................................................235 Adding protocol measurements........................................................................................239 Creating pressure-volume loop measurements in M-Mode..........................................
Chapter 36: Analyzing M-Mode images f To place a depth interval measurement: 1. Click the depth interval measurement button . The system highlights the button until you complete your measurement. 2. Click on your image to place the initial caliper. 3. Trackball to the location where you want to end your measurement and then click to place the end caliper. 4. If you need to move the entire measurement, click on a measurement line and then drag and drop it.
Chapter 36: Analyzing M-Mode images 3. Trackball to the same location on the next cardiac cycle and click to place the next caliper. 4. Continue placing calipers on the cardiac cycles and then right-click on the last heart beat of the sequence to place your final caliper. 5. If you need to move the entire measurement, click on a measurement line and then drag and drop it.
Chapter 36: Analyzing M-Mode images f Refine the trace (page 238) To trace the outer LV walls as well as the inner LV walls: Use the same peak and valley caliper points tracing method, but also trace the outer LV walls using the following procedure: 1. On the upper wall, trace the outside wall along the number of cycles you want to measure and then right-click to complete the trace. The outside wall is far less dynamic than the inner wall. 2.
Chapter 36: Analyzing M-Mode images f 2. The system automatically adds points along the tissue layer. 3. Depending on the placement of the initial points, the Refine feature might produce less than optimal results. To return to the initial trace, right-click the trace and select Undo Last Action. To refine all the trace lines in your LV trace: 1. Right-click on any of the lines on your trace and select Refine All. 2. The system refines the contours of all the lines in your trace. 3.
Chapter 36: Analyzing M-Mode images f If you are in the Study Browser, open an image and then press Measure . To place a protocol measurement: 1. In the measurement packages drop-down list click the appropriate package. 2. In the list of protocols, select the appropriate protocol. 3. In the list of measurements, select the measurement you want to add. The system automatically activates the appropriate measurement tool and highlights the generic button for that tool. 4.
Chapter 36: Analyzing M-Mode images Adding M-Mode measurement chains In M-Mode, the most precise way to create diastole and systole measurement sets is to stack your measurements. To automate this procedure the system automatically links the following measurements into chained sequences.
Chapter 36: Analyzing M-Mode images f To see the label for any measurement you must either: Complete the remaining measurements in the chain Complete another measurement Return to the Study Browser and open the image Creating pressure-volume loop measurements in M-Mode Pressure-volume (PV) loop measurements provide a graphical method of identifying and evaluating LV pressure-volume relationship changes related to dynamic levels of cardiac stress.
Chapter 36: Analyzing M-Mode images 4. The system calculates the pressure-volumes of the cardiac cycles and plots them as a graph on the Pressure Volume Relationship window.
Chapter 36: Analyzing M-Mode images If the graph displays a single loop, the system plots a red dot on the curve at the End Diastolic point. If the graph displays multiple loops, the system plots a best-fit line through the End Diastolic points. Average check box Check this box to display a loop that represents a virtual or averaged cardiac cycle, calculated from the aggregate cycles defined by each LV wall trace. Clear the check box to display all cardiac cycle instances.
Section 10 PW Doppler Mode imaging and analysis PW Doppler Mode (Pulsed Wave Doppler) is an ultrasound mode you can use to measure the velocity and direction of flow. The Vevo software presents the detected PW Doppler signal as both a spectral image in the display window as well as an audio output through the system speakers. In This Section Acquiring PW Doppler Mode and PW Tissue Doppler Mode images ........................246 Acquiring PW Tissue Doppler Mode images .......................................
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Chapter 37 Acquiring PW Doppler Mode and PW Tissue Doppler Mode images This chapter shows you how to acquire PW Doppler Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical PW Doppler Mode image acquisition session ...................................................246 PW Doppler Mode window workspace.....................
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images 3. Adjust the Image Width control to remove image content outside the region of interest to optimize the image data for analysis. 4. Press PW . The system displays the yellow sample volume overlay on the B-Mode image. 5. Press PW again. The dual-window PW Doppler Mode workspace appears. The PW Doppler Mode window is on the bottom, the B-Mode scout window is on the top. 6.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Area Description PW Doppler Mode Image area export zone. When you export a stored image and configure your export to send only the Image Area, this is the area of the window that the system exports, along with header information. B-Mode scout window. Shows you precisely where the region of interest is. The region of interest is located between the yellow wireframe brackets set.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Area Description Blockout zones. In PW Doppler Mode, the system processes reliable ultrasound signals it receives from just beyond the face of the transducer and extending until the distance is too far to produce reliable data. The surface blockout zone is the very small distance just beyond the transducer face.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Area Description Physiological data trace window. Displays your animal's heart rate, temperature, respiration rate and blood pressure data. During data acquisition this information comes from the Advanced Physiological Monitoring Unit connected to the Vevo Imaging Station. Cine loop time scale. In milliseconds.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Control panel controls for PW Doppler Mode When you are acquiring PW Doppler Mode image data, these are the controls you use to optimize the image you see on the screen. Transmit Power Adjusts the power of the ultrasound signal transmission. Turn clockwise to increase power. Turn counterclockwise to decrease power. Between 1% and 10% power the control adjusts power in increments of 1%.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Volume Adjusts the speaker volume for the PW Doppler Mode and PW Tissue Doppler Mode audio data that the system acquires along with the spectral data. To use this dial control: Turn clockwise to increase the volume. Turn counterclockwise to decrease the volume. Active during: PW Doppler Mode and PW Tissue Doppler Mode image acquisition and review sessions.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Doppler Gain Adjusts the frequency shift in increments of 1.0 dB. Turn clockwise to add gain and brighten the Doppler data. Turn counterclockwise to reduce gain and darken the data. Active during: PW Doppler Mode, PW Tissue Doppler Mode, Color Doppler Mode, Power Doppler Mode image acquisition sessions.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Simul This toggle control sets the system to acquire live data simultaneously in both the BMode scout window as well as the PW Doppler image window. In the dual window view, use this feature when you want to adjust your sample volume in the B-Mode scout window while you view the waveform data in the PW Doppler Mode window. To use this toggle control: 1. Press to activate the simultaneous state.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images SV/Gate Push up to increase. Pull back to decrease. In PW Doppler Mode: This control adjusts the distance in mm of the vertical line between the two yellow calipers of the sample volume. In the dual window view, the system displays the spectral data that the system acquires along this line. Current data is on the right side, trailing data extends to the left.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Velocity Adjusts the PRF (pulse repetition frequency). The higher you set the PRF, the lower the signal resolution. In PW Doppler Mode: Adjust the range of the scale of the Y axis on the Power Doppler Mode image window by adjusting the pulse rate frequency of the ultrasound signal. Use this control when the spectral waveform is either too compressed or too expanded for your purposes.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Acquisition Parameter Description Doppler Gain The PW Doppler frequency, measured in dB. Adjust with the Doppler Gain control. Beam Angle The number of degrees of steer to the ultrasound beam so you generate flow direction information when the orientation of your target vessel is perpendicular or almost perpendicular to your ultrasound beam. Adjust with the Beam Angle control.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images f To set your PW Doppler SV: 1. Begin acquiring data in Power Doppler Mode and position your transducer to display your region of interest in the center of the B-Mode scout window. 2. If the PW Doppler Mode acquisition settings (page 256) are not displayed in the left panel press Mode Settings . 3. Watching the B-Mode scout window, trackball to move the yellow wireframe as close as possible to your region of interest. 4.
Chapter 37: Acquiring PW Doppler Mode and PW Tissue Doppler Mode images Tip: If your transducer supports beam angle adjustments, adjust the Beam Angle to steer the beam to reduce the angle enough that the SV is no longer in the blockout zone. Exporting PW Doppler Mode cine loop audio The system acquires PW Doppler Mode data as both visual and audio data. You can export this data as a cine loop as either an integrated audiovisual file using the AVI file format, or as audio-only using the WAV file format.
Chapter 38: Acquiring PW Tissue Doppler Mode images Chapter 38 Acquiring PW Tissue Doppler Mode images PW Tissue Doppler Mode uses PW Doppler ultrasound to measure the velocity function of myocardial tissue, typically during the diastolic phase of the cardiac cycle. This chapter shows you how to acquire PW Tissue Doppler Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated.
Chapter 38: Acquiring PW Tissue Doppler Mode images Analyzing PW Tissue Doppler Mode images You analyze PW Tissue Doppler Mode images using the same tools that you use to analyze PW Doppler Mode images. For complete information, see Analyzing PW Doppler Mode images (page 262). Rev 1.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images Chapter 39 Analyzing PW Doppler Mode and PW Tissue Doppler Mode images This chapter shows you how to analyze PW Doppler Mode and PW Tissue Doppler Mode images that are saved to a study. In this chapter Adding generic PW Doppler Mode measurements........................................................262 Applying automatic traces to the frequency waveform.................................................267 Adding protocol measurements.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images f To place an acceleration measurement: 1. While you view a saved image from the Study Browser or an image that is acquired but not stored during an image acquisition session, press Measure and toggle to view the measurement tools panel. 2. Click the Acceleration measurement button . The system highlights the button until you complete your measurement. 3. Click on your image to place the initial caliper. 4.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images 3. Click on your image to place the initial caliper at a specific point on the waveform. 4. Trackball along the contour of the waveform. The system automatically places points at the spacing density that you specify in the Auto Point Spacing section of the Measurement tab in the Preferences window. 5. Right-click to place your final caliper at the end of the last cardiac cycle.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images VTI measurement with automatic frequency trace When you want to measure VTI over a series of cycles, use the automatic frequency trace feature to instantly plot the caliper points on your frequency waveform before you apply the VTI measurement. f To place a VTI measurement with automatic frequency trace: 1.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images Related information Analyzing image data (page 156) Applying automatic traces to the frequency waveform (page 267) Heart rate measurement Use the heart rate measurement tool for measuring the average heart rate (in BPM) of an animal by measuring the distance over time between the displayed cardiac cycles. f To place a heart rate measurement: 1. Click the heart rate measurement button . 2.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images 3. Click on your image to place the single caliper dot. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement Doppler Point #, where # is a sequential number. 4.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images You can apply these traces in real-time to the data in your cine loop acquisition buffer or to an acquired cine loop. f To apply an automatic trace of the frequency waveform: 1. While you view a saved image from the Study Browser or an image that is acquired but not stored during an image acquisition session, press Measure and toggle to view the measurement tools panel. 2.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images Option auto Description Applies a green trace to the largest velocity values, positive and negative, along the entire cine loop. Mean Option none Description The system does not apply a trace. + Applies a blue trace to all positive mean frequency signal traces along the entire cine loop. - Applies a purple trace to all negative mean frequency signal traces along the entire cine loop.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images Adding protocol measurements Protocol measurements are labeled uniquely for a specific measurement protocol. f f 270 To access the protocol measurement tools and measurements list Scan/Freeze If you are in an image acquisition session press image and then press Measure . to acquire an If you are in the Study Browser, open an image and then press Measure . To place a protocol measurement: 1.
Chapter 39: Analyzing PW Doppler Mode and PW Tissue Doppler Mode images The system automatically activates the appropriate measurement tool and highlights the generic button for that tool. 4. On the image, add your measurement. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement. Next step Reporting your analysis results (page 184) Related information Rev 1.
Section 11 3D-Mode imaging and analysis 3D-Mode provides tools you can use to: Create and manipulate three-dimensional renderings Make volumetric measurements of objects viewed with high-resolution ultrasound In This Section How 3D-Mode works .........................................................................................................273 Acquiring 3D-Mode images...............................................................................................275 Analyzing 3D-Mode images ...
Chapter 40: How 3D-Mode works Chapter 40 How 3D-Mode works 3D-Mode acquires a series of 2-dimensional “slices” and assembles them into a 3D data set. The 3D data set can then be visualized and manipulated. Targets (for example, tumor growth) can be segmented and volumetric measurements made. 3D imaging can be used in B-Mode, Power Doppler Mode and Contrast Mode imaging procedures. 3D-Mode hardware setup The transducer is mounted on a Vevo Imaging Station equipped with a 3D motor stage.
Chapter 40: How 3D-Mode works attached transducer, travels in a direction perpendicular to the imaging orientation. At each step, the transducer acquires a two-dimensional slice of the B-Mode, Power Doppler Mode, or Contrast Mode image. 3D tor mo ck tra e g sta Tran sd ucer beam p lane Each two-dimensional B-Mode, Power Doppler Mode, or Contrast Mode image slice is assembled with the other slices of acquired data and rendered by the Vevo software into a three-dimensional data set.
Chapter 41: Acquiring 3D-Mode images Chapter 41 Acquiring 3D-Mode images This chapter shows you how to acquire 3D-Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical 3D-Mode image acquisition session ...................................................................275 3D-Mode window workspace ...........................................................................................
Chapter 41: Acquiring 3D-Mode images a. Initializes the motor stage. b. Confirms the initialization and prompts you to start the 3D slices acquisition. 3. Click OK. The system returns to the base image acquisition Mode. 4. Activate the base imaging Mode for the type of 3D-Mode image you want to acquire: 5. Press B-Mode to acquire a B-Mode only 3D image. The system begins to acquire B-Mode image data. Press Power to acquire Power Doppler Mode 3D image data over each BMode image slice.
Chapter 41: Acquiring 3D-Mode images The system displays the 3D Acquisition Setup box. 7. Set up your 3D-Mode image slices parameters as described in the following table. 3D parameter Description Scan Distance Sets the distance (in millimeters) that the 3D motor stage will travel during the entire 3D image acquisition. Scan distance ranges between 0.5 mm and 38 mm. Step Size Sets the distance that the 3D motor stage travels between each B-Mode slice. Step sizes ranges between 0.03 mm and 0.5 mm.
Chapter 41: Acquiring 3D-Mode images When the 3D motor stage finishes acquiring the 3D slices: The system positions the transducer at the center of its range. The system assembles the 3D image data set and displays the data in the four-pane view. Cine Store or Frame Store 9. Press to save the 3D image data. 10. Press Close . The system closes the series you are working on and displays the Study Information window. 11. Complete the required fields to define your study and click OK.
Chapter 41: Acquiring 3D-Mode images 3D-Mode window workspace The 3D-Mode window is the workspace you use whenever you visualize acquired image data in 3D-Mode. The following illustration and table describes the information and features in the 3D-Mode window. Area Description Image data area. Includes the view panes area and the visualization options tool bar. View panes area. The system defaults to four view panes (Quad Pane view) , but you can select Dual Pane view or Single Pane view.
Chapter 41: Acquiring 3D-Mode images Area Description Active pane menu drop-down icon. When you are in the cube view, click to display the available commands that apply to the image in the active pane. Not all panes include the same commands.
Chapter 41: Acquiring 3D-Mode images Area Description Image management panel. Press the appropriate control to display the image management panel you want to work with. Press Mode Settings to toggle between the acquisition Mode settings and the 3D-Mode analysis tools. The 3D-Mode tools each provide a unique set of commands and controls for each tool. These appear beneath the tool buttons. Click the tool button to work with the commands and controls.
Chapter 41: Acquiring 3D-Mode images If you are acquiring a Power 3D-Mode image: a. Start Power Doppler Mode. b. Use the Control panel controls for Power Doppler Mode (page 327) to optimize your image. c. Press 3D to set up the automated image acquisition. If you are acquiring a Contrast 3D-Mode image: a. Start Contrast Mode. b. Use the Control panel controls for Contrast Mode (page 345) to optimize your image. c. Press 3D to set up the automated image acquisition.
Chapter 41: Acquiring 3D-Mode images f To connect the 3D motor stage to the Vevo Imaging Station: 1. Insert the quick release post into the quick release mount located on the Imaging Station arm. Quick release post Quick release mount 2. Carefully line up the holes on the post with the pins on the quick release mount. 3. Finger tighten the knob on the quick release mount. 4. Connect the 3D motor cable to the 3D Motor connector on the rear panel of the Vevo 2100 Imaging System.
Chapter 41: Acquiring 3D-Mode images 3D motor stage Transducer clamp Transducer 3. Lift the latch to open the clamp and then place the collar of the transducer in the clamp. Latch Moving arm Set screw 284 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 41: Acquiring 3D-Mode images Rev 1.1 4. Close the moving arm of the clamp and then pull the latch down to the 45º notch. This transducer rotation lock setting holds the transducer but provides enough freedom for your to rotate it. 5. To set the transducer to any of the at the desired 90-degree angle in the clamp turn the transducer until you feel the collar snap into position. 6. Close the clamp and push the latch down until it locks into place as shown in the following illustration.
Chapter 41: Acquiring 3D-Mode images Orienting the transducer As shown in the following illustration, the long axis of the 3D motor stage must be aligned in the direction that the transducer travels during data acquisition. 3D motor stage Direction of travel: transducer c sli ge a Im e g nin an Sc n e pla During the 3D data acquisition, the motor stage moves the transducer.
Chapter 41: Acquiring 3D-Mode images Mode Settings . If you are on the Vevo 2100 Imaging System, press If you are on the Vevo Imaging Workstation, click 3D Settings. 2. Click Record and then click Start Recording. 3. In the Save As box: a. Browse to the directory where you want to save the recording. b. If you want to create a new folder for the recording, click New Folder and add the new folder. c. If you want to change the file name, in the Save As field, type a unique file name. d.
Chapter 42: Analyzing 3D-Mode images Chapter 42 Analyzing 3D-Mode images This chapter shows you how to analyze 3D-Mode images that are saved to a study. In this chapter 3D-Mode visualization tools..............................................................................................288 Manipulating 3D-Mode image data..................................................................................290 Creating 3D volume measurements ...................................................................
Chapter 42: Analyzing 3D-Mode images Click to magnify the view up to 20 levels of zoom. Zoom In Click to minimize the view up to 20 levels of zoom. Zoom Out Cube View Click to display a three-dimensional view of the acquired data, constructed from the full set of BMode image slices. The cube displays a blue wireframe by default. As you trackball over a plane on the cube, the plane becomes “active” and the wire-frame for that plane is displayed in green.
Chapter 42: Analyzing 3D-Mode images Coronal View Surface View Click to display a straight-on perspective of the x-z plane image slice, displayed on the Cross view as the plane outlined in red. Click to display a compilation view that uses the Cross view to map operator-generated volumes to the acquired data.
Chapter 42: Analyzing 3D-Mode images Rendering a 3D image Use the Render tool in 3D-Mode to display the full 3D image. You can only use this tool when you are viewing your 3D image in the Cube view. f To render an image: 1. While you analyze your 3D-Mode image, to view the 3D-Mode tools set in the left panel: Mode Settings . If you are on the Vevo 2100 Imaging System, press If you are on the Vevo Imaging Workstation, click 3D Settings. 2. Click Render. 3.
Chapter 42: Analyzing 3D-Mode images Render mode Description Render Render mode displays the full 3D image in the Cube view. To render a 3D image: Under Mode, click Render. The Cube view traces each line of the data, perpendicular to the display for the full image. The left panel adds the Opacity & Luminance section for B-Mode image data under the Mode section. Use the light-red Opacity curve to adjust the levels of transparency in the image.
Chapter 42: Analyzing 3D-Mode images Render mode Description MIP (Min) MIP (Min) (Minimum Intensity Persistence) enhances the contrast of an image by minimizing the brightest pixels in the image. Use this mode to better distinguish organs from their surrounding area when the organ objects are darker than their surrounding structures. To apply MIP (Min) to a 3D image: Under Mode, click MIP (Min).
Chapter 42: Analyzing 3D-Mode images Sculpting mode Description Shave Shave gives you fine control over the amount of data you want to cut away. This mode functions like an eraser: set the depth that the tool can shave the target and then use the tool on the image in Cube view. To shave a 3D image dataset: 1. Under Mode, click Shave. 2. Under Depth, set the slider to the depth of shave required. Depth slider values are proportional. The Max setting represents the full distance through the image.
Chapter 42: Analyzing 3D-Mode images Sculpting mode Description Scalpel (Outside) Scalpel (Outside) mode functions like a cookie cutter, much the same way as Scalpel (Inside). Select a depth, then outline an area outside of which to remove data. To scalpel outside a 3D image: 1. Under Mode, click Scalpel (Outside). 2. Under Depth, set the slider to the required depth. 3. Trackball over the image. 4. Drag to create the outline of the area to be scalpeled. 5. Release the trackball button.
Chapter 42: Analyzing 3D-Mode images Rotational segmentation f To create a volume measurement using rotational segmentation: 1. While you analyze your 3D-Mode image, to view the 3D-Mode tools set in the left panel: Mode Settings . If you are on the Vevo 2100 Imaging System, press If you are on the Vevo Imaging Workstation, click 3D Settings. 2. Click Volume. 3. Ensure that the 3D data is displayed in the Cube view. 4. In the Volume area: a. Select Rotational. b.
Chapter 42: Analyzing 3D-Mode images The system prompts you to set a Rotational Axis. You can set the axis of rotation by clicking once at one end of the axis of rotation and then clicking at the other end. The axis of rotation should run through entire volume region as shown in the following illustration: c. Click to create a point on the circumference of a contour. d. Trace the contour. The system adds points as you trace. e.
Chapter 42: Analyzing 3D-Mode images 6. 7. Select the preferred rotational segmentation parameters in the Segmentation section of the Volume tool. Set the desired Method of segmentation: Auto or Semi. Set the Angle of rotation. The angle represents the degrees separating each contour. The default value is 18 degrees. Set the Direction of rotation: Clockwise or Counterclockwise, relative to the axis of rotation. If Semi was selected as the method of segmentation, select the Step Num value.
Chapter 42: Analyzing 3D-Mode images 2. Click Volume. 3. Ensure that the 3D data is displayed in the Cube view. 4. In the Volume area: a. Select Parallel. b. If you want to assign a color to the contours of the volume click Color, select the appropriate color from the Color dialog, and then click OK. c. 5. Click Start. To create the first contour, start in the Cube view and then complete the following procedures: a. Click to create a point on the circumference of a contour. b.
Chapter 42: Analyzing 3D-Mode images Initial contour 6. Refined contour You can draw subsequent contours can be drawn manually or semiautomatically. Select the preferred parallel segmentation parameters in the Segmentation area of the Volume tool. a. Set the Step Size. The default step size is the scan step size. b. Set the Direction of segmentation: Inward, Outward, or Both. c. Set whether you are going to use manual or semi-automatic segmentation.
Chapter 42: Analyzing 3D-Mode images 4. f Click Refine to use the edge detection feature to fit the contour in line with the new point. To move a contour: 1. Click between the caliper points on the contour. This selects the entire contour. 2. Drag the contour to the new location. Displaying a volume measurement as a 3D object f To display a volume measurement as a 3D object: 1. On the visualization tools tool bar, click the Surface View icon.
Chapter 42: Analyzing 3D-Mode images The system displays the measurement tools at the top of the left panel. Hover over a tool to see the description label. Linear distance measurement Linear distance is measured in mm. f To place a linear distance measurement: 1. Click the linear distance measurement button . 2. Click on your image to place the initial caliper. 3. Trackball to the location where you want to end your measurement and then click to place the end caliper.
Chapter 42: Analyzing 3D-Mode images tab of the Preferences window, the system displays the measurement value and editable label for the measurement. 5. If you need to move the entire measurement, click on a measurement line and then drag and drop it. Related information Rev 1.
Section 12 Color Doppler Mode imaging and analysis Color Doppler uses PW Doppler Mode ultrasound to produce an image of a blood vessel. In addition, the system converts the Doppler sounds into colors that are overlaid on the image of the blood vessel to represent the speed and direction of blood flow through the vessel. In This Section Acquiring Color Doppler Mode images...........................................................................305 Analyzing Color Doppler Mode images .......................
Chapter 43: Acquiring Color Doppler Mode images Chapter 43 Acquiring Color Doppler Mode images This chapter shows you how to acquire Color Doppler Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical Color Doppler Mode image acquisition session ...............................................305 Color Doppler Mode window workspace ...............................................................
Chapter 43: Acquiring Color Doppler Mode images b. Trackball up or down to change the height of the box, or left and right to change the width of the box. c. Press Update to return to the solid-lined color ROI box. 3. To change the position of the box, trackball to move the color ROI box. 4. Press Presets to cycle through the available presets and then select an appropriate set of optimized image acquisition settings. 5.
Chapter 43: Acquiring Color Doppler Mode images Color Doppler Mode window workspace The Color Doppler Mode window is the workspace you use whenever you view image data in Color Doppler Mode. The following illustration and table describes the information and features in the Color Doppler Mode window. Area Description Image area export zone.
Chapter 43: Acquiring Color Doppler Mode images Area Description Region of interest color box overlay. The system applies the Color Doppler Mode based colors only to the image data within this box. Vascular flow moving toward the transducer. Displayed in red colors. Vascular flow moving away from the transducer. Displayed in blue colors. Color and velocity scale. The right column of the scale is the color scale.
Chapter 43: Acquiring Color Doppler Mode images Area Description Left panel. Displays a unique set of controls and information sections depending on the control key you press: Press Mode Settings to set the panel to display the Mode settings. This is the default panel when you open a Mode window. Press Measure to set the panel to display the measurement tools. These tools are not available when you are acquiring or reviewing images.
Chapter 43: Acquiring Color Doppler Mode images Frequency Adjusts the transmit frequency of the transducer between the higher and lower frequency levels that are supported by the specific transducer. When you increase the frequency you can improve detail at the focus depth but the system tends to lose detail at deeper tissues. Push forward to increase the frequency. Pull back to decrease the frequency.
Chapter 43: Acquiring Color Doppler Mode images Color Activates Color Doppler Mode acquisition and begins displaying the color box overlay over the B-Mode background image. Doppler Gain Adjusts the frequency shift in increments of 1.0 dB. Turn clockwise to add gain and brighten the Doppler data. Turn counterclockwise to reduce gain and darken the data. Active during: PW Doppler Mode, PW Tissue Doppler Mode, Color Doppler Mode, Power Doppler Mode image acquisition sessions.
Chapter 43: Acquiring Color Doppler Mode images Beam Angle Helps you generate flow direction information when the orientation of your target vessel is perpendicular or almost perpendicular to your ultrasound beam. This control applies a graduated series of transmission and reception delays to the ultrasound sound signals of each crystal in the transducer. These carefully calibrated sequences can effectively steer the ultrasound beam in order to detect minute frequency shifts.
Chapter 43: Acquiring Color Doppler Mode images Sensitivity Adjusts the signal-to-noise ratio so that you can: Better identify weak-signal targets in the near field that are difficult to distinguish because they are very small Better identify large targets in the far field that are difficult to distinguish because the signal is so attenuated at depth. The higher you set the sensitivity level, the lower the system sets the frame rate. Push up to increase sensitivity. Pull down to decrease.
Chapter 43: Acquiring Color Doppler Mode images Parameter Description Width The width of the acquired image area, measured in mm. Adjust with the Image Width control. Beam Angle The number of degrees of steer to the ultrasound beam so you generate flow direction information when the orientation of your target vessel is perpendicular or almost perpendicular to your ultrasound beam. Adjust with the Beam Angle control. Sensitivity The signal resolution level. Adjust with the Sensitivity control.
Chapter 44: Analyzing Color Doppler Mode images Chapter 44 Analyzing Color Doppler Mode images This chapter shows you how to analyze Color Doppler Mode images that are saved to a study. In this chapter Adding generic Color Doppler Mode measurements ....................................................315 Adding protocol measurements........................................................................................
Chapter 44: Analyzing Color Doppler Mode images 2. Click on your image to place the initial caliper. 3. Trackball to the location where you want to end your measurement and then click to place the end caliper. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement. 4. If you need to move the entire measurement, click on a measurement line and then drag and drop it.
Chapter 44: Analyzing Color Doppler Mode images applies to 2D area measurements in B-Mode, 3D-Mode, and Contrast Mode as well as for 3D-Mode volume contours. 4. The system adds the final line segment to connect your last caliper with your first. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement. 5.
Chapter 44: Analyzing Color Doppler Mode images 2. In the physiology data trace window below the image mode data, click to place the initial caliper. 3. Trackball to the location where you want to place your end caliper and then click to place the caliper. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement. 4.
Chapter 44: Analyzing Color Doppler Mode images 3. In the list of measurements, select the measurement you want to add. The system automatically activates the appropriate measurement tool and highlights the generic button for that tool. 4. On the image, add your measurement. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement.
Section 13 Power Doppler Mode imaging and analysis Power Doppler Mode displays the energy from the returning Doppler signal and assigns a color range to the energy generated by moving blood flow. Power Doppler. In This Section Acquiring Power Doppler Mode images .........................................................................321 Analyzing Power Doppler Mode images.........................................................................
Chapter 45: Acquiring Power Doppler Mode images Chapter 45 Acquiring Power Doppler Mode images This chapter shows you how to acquire Power Doppler Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical Power Doppler Mode image acquisition session ..............................................321 Typical Power 3D-Mode image acquisition session ....................................................
Chapter 45: Acquiring Power Doppler Mode images a. Press Update . The color ROI box becomes a dashed-line box. b. Trackball up or down to change the height of the box, or left and right to change the width of the box. c. Press Update to return to the solid-lined color ROI box. 3. To change the position of the box, trackball to move the color ROI box. 4. Adjust the Image Width control to remove image content outside the region of interest to optimize the image data for analysis. 5.
Chapter 45: Acquiring Power Doppler Mode images f To segment a volume in Power 3D-Mode: 1. Acquire your Power 3D-Mode image. 2. Follow the same procedures for segmenting a volume in 3D-Mode: Create a volume using rotational segmentation (page 296) Create a volume using parallel segmentation (page 298) The system displays a Percent Vascularity (PV) value below the image. This PV value quantifies the relative percentage of flow or other movement. 3.
Chapter 45: Acquiring Power Doppler Mode images The system acquires the Power 3D-Mode image slices and then displays the data in the 3D-Mode workspace. Related information 324 3D-Mode visualization tools (page 288) Typical 3D-Mode image acquisition session (page 275) Typical Contrast 3D-Mode image acquisition session (page 341) VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Chapter 45: Acquiring Power Doppler Mode images Power Doppler Mode window workspace The Power Doppler Mode window is the workspace you use whenever you view image data in Power Doppler Mode. The following illustration and table describes the information and features in the Power Doppler Mode window. Area Description Image area export zone.
Chapter 45: Acquiring Power Doppler Mode images Area Description Micro-ultrasound image. Displays the B-Mode data that the transducer acquires. When you review an image, this is the workspace where you use the image measurement tools to apply your measurements. Power box overlay. The system applies the Power Doppler Mode based colors only to the image data within this region-of-interest box. Gray scale and power scale. The right column of the scale is the power scale.
Chapter 45: Acquiring Power Doppler Mode images Control panel controls for Power Doppler Mode When you are acquiring Power Doppler Mode image data, these are the controls you use to optimize the image you see on the screen. Frequency Adjusts the transmit frequency of the transducer between the higher and lower frequency levels that are supported by the specific transducer. When you increase the frequency you can improve detail at the focus depth but the system tends to lose detail at deeper tissues.
Chapter 45: Acquiring Power Doppler Mode images Transmit Power Adjusts the power of the ultrasound signal transmission. Turn clockwise to increase power. Turn counterclockwise to decrease power. Between 1% and 10% power the control adjusts power in increments of 1%. Between 10% to 100% power the control adjusts in increments of 10%. Line Density Adjusts the resolution of your image by adjusting how many lines of image data the transducer acquires over your image area.
Chapter 45: Acquiring Power Doppler Mode images Doppler Gain Adjusts the frequency shift in increments of 1.0 dB. Turn clockwise to add gain and brighten the Doppler data. Turn counterclockwise to reduce gain and darken the data. Active during: PW Doppler Mode, PW Tissue Doppler Mode, Color Doppler Mode, Power Doppler Mode image acquisition sessions. Power Activates Power Doppler Mode acquisition and begins displaying the power box overlay over the B-Mode background image.
Chapter 45: Acquiring Power Doppler Mode images Beam Angle Helps you generate flow direction information when the orientation of your target vessel is perpendicular or almost perpendicular to your ultrasound beam. This control applies a graduated series of transmission and reception delays to the ultrasound sound signals of each crystal in the transducer. These carefully calibrated sequences can effectively steer the ultrasound beam in order to detect minute frequency shifts.
Chapter 45: Acquiring Power Doppler Mode images Power Doppler Mode acquisition settings f To view the Power Doppler Mode acquisition settings: Press Mode Settings . The Power Doppler Mode acquisition settings panel displays the following parameters, in addition to labeling the current transducer application and preset: Transmit Parameter Description Frequency The ultrasound frequency, measured in MHz. Adjust with the Frequency control.
Chapter 45: Acquiring Power Doppler Mode images Display 332 Parameter Description Dynamic Range The contrast of your image, measured in dB. Adjust with the Dynamic Range control. Persistence The state of the Persistence feature: Off, Low, Med, High, Max. Adjust with the Persist control. Line Density The line density level. One of four settings: Quarter, Third, Half, Full. Adjust with the Line Density control. Display Map The selected predefined display map from the predefined set of maps.
Chapter 46: Analyzing Power Doppler Mode images Chapter 46 Analyzing Power Doppler Mode images This chapter shows you how to analyze Power Doppler Mode images that are saved to a study. In this chapter Adding generic Power Doppler Mode measurements...................................................333 Adding generic Power Doppler Mode measurements Power Doppler Mode provides seven generic measurement tools. Use these tools when you want to add measurements that aren't part of a measurement protocol.
Chapter 46: Analyzing Power Doppler Mode images 2. In the physiology data trace window below the image mode data, click to place the initial caliper. 3. Trackball to the location where you want to place your end caliper and then click to place the caliper. 4. If you need to move the entire measurement, click on a measurement line and then drag and drop it. Related information Complete procedure for adding a measurement (page 166) Linear distance measurement Linear distance is measured in mm.
Chapter 46: Analyzing Power Doppler Mode images Related information Complete procedure for adding a measurement (page 166) 2D Area measurement 2D Area is measured in mm2. f To place a 2D area measurement: 1. Click the 2D area measurement button . 2. Click on your image to place the initial caliper. 3. Trackball along the contour of your target tissue and then right-click to place your last caliper.
Chapter 46: Analyzing Power Doppler Mode images 4. Trackball to the position where you want to end the second ray and then click to place the final caliper. If you selected the Show Values and Labels option in the Measurements tab of the Preferences window, the system displays the measurement value and editable label for the measurement. 5. If you need to move the entire measurement, click on a measurement line and then drag and drop it.
Section 14 Contrast Mode imaging and analysis Contrast Mode imaging provides tools to detect and quantify vascular structures and dynamics at the molecular level.
Chapter 47: Acquiring Contrast Mode images Chapter 47 Acquiring Contrast Mode images This chapter shows you how to acquire Contrast Mode images. WARNING: High levels of ultrasound energy can damage tissue. Do not touch the transducer when acoustic power could be generated. In this chapter Typical Contrast Mode image acquisition session..........................................................338 Typical Contrast 3D-Mode image acquisition.................................................................
Chapter 47: Acquiring Contrast Mode images 3. Acquire 100 to 200 frames of data and then save and label the cine loop as Baseline. 4. Press Pre Trigger and inject the contrast agent. If you selected Auto SAVE on Scan Completion for Contrast Mode in the General tab of the Preferences window the system saves the cine loop when the acquisition ends. You have created a cine loop of the bolus injection. f To automatically create a contrast agent destruction cine loop: Contrast 1.
Chapter 47: Acquiring Contrast Mode images You have successfully acquired the contrast data that the system can work with to isolate the contrast agent ultrasound signal data from the tissue ultrasound signal data. The contrast overlay data is created by comparing the baseline data acquired before the injection of the contrast agent with the data acquired after the injection. This, in theory, isolates only the signal from the contrast agent. f To create the reference set: Cine Loop Review 1.
Chapter 47: Acquiring Contrast Mode images The transducer transmits a single ultrasound pulse burst at maximum setting for the period defined in the Contrast Mode preferences. 4. Press Cine Store .
Chapter 47: Acquiring Contrast Mode images Cine Store 9. Press . 10. Click Create Reference. 11. Press Study Management and then open the first Contrast Mode cine loop you acquired before you ran the destruction sequence. 12. Click Process Cine. The system generates the green contrast overlay data. 13. Click Load into 3D. The system generates the Contrast 3D-Mode data and opens the image in the four-pane Contrast 3D-Mode window. 14.
Chapter 47: Acquiring Contrast Mode images Contrast Mode window workspace The Contrast Mode window is the workspace you use whenever you view image data in Contrast Mode. The following illustration and table describes the information and features in the Contrast Mode window. Area Description Image area export zone. When you export a stored image and configure your export to send only the Image Area, this is the area of the window that the system exports, along with header information. Image scale.
Chapter 47: Acquiring Contrast Mode images Area Description Orientation icon. Indicates the position of the orientation ridge of your transducer in relation to your image. If the image orientation looks backward to you, click this icon to flip the image view left/right. Green scale and gray scale. The left column of the scale is the green scale. It indicates the dynamic range of the contrast intensity. The right column of the scale is the gray scale for the B-Mode background image.
Chapter 47: Acquiring Contrast Mode images Area Description Contrast acquisition tools. Tool Description Create Reference Processes the data reference set that is defined by the length of the cine range. Contrast DR Displays the intensity level of the green overlay. Threshold Eliminates overlay data that is not relevant to your contrast agent by specifying the level at which the system displays no contrast image data. Process Cine Creates the contrast overlay.
Chapter 47: Acquiring Contrast Mode images Burst Transmits an ultrasound pulse at maximum setting. This destroys the contrast agent in the region of interest. In the cine loop the system displays a vertical green bar to mark the destruction event. Pre Trigger In Contrast Mode, starts an analysis based on the number of frames defined in the General tab of the Preferences window.
Chapter 47: Acquiring Contrast Mode images Contrast Mode acquisition settings f To view the Contrast Mode acquisition settings: Press Mode Settings . The Contrast Mode acquisition settings panel displays the following parameters, in addition to labeling the current transducer application and preset: Transmit Parameter Description Frequency The ultrasound frequency, measured in MHz. Adjust with the Frequency control.
Chapter 47: Acquiring Contrast Mode images Contrast agent technology Contrast Mode imaging requires the use of contrast agents. Contrast agents are gas-filled microbubbles that produce a strong echogenic signal when excited with an ultrasound pulse. VisualSonics provides a family of contrast agent kits for targeted and nontargeted applications.
Chapter 47: Acquiring Contrast Mode images f 2. Drag the frame indicator into the range of frames after the vertical green bar which identifies the destruction burst event. 3. Turn Screen Keys until Display Color appears in the control panel feedback display. 4. Press to cycle through the following display options: Contrast overlay only B-Mode image only Contrast overlay and B-Mode image To display the contrast data as an overlay using the workstation: 1.
Chapter 47: Acquiring Contrast Mode images B-Mode image only Contrast overlay and B-Mode image Related information Adjusting the contrast overlay display (page 350) Image Sequence (page 412) Adjusting the contrast overlay display You can modify the amount and intensity of the contrast green overlay data in three ways: Adjust the process persistence filter Adjust the contrast overlay dynamic range Adjust the contrast overlay data threshold Adjusting the contrast processing filter
Chapter 47: Acquiring Contrast Mode images Adjusting the contrast dynamic range Contrast DR is a dynamic range control that modifies the intensity of the contrast data overlay. You can set the value from 5dB-50dB. The lower you set the dynamic range, the more intense the contrast data appears. f To adjust the contrast overlay dynamic range: 1. In the Contrast DR slider control, drag or click in the range bar to coarsely set your contrast. 2.
Chapter 48: Analyzing Contrast Mode images Chapter 48 Analyzing Contrast Mode images This chapter shows you how to analyze Contrast Mode images that are saved to a study. In this chapter Adding generic Contrast Mode measurements ..............................................................352 Adding generic Contrast Mode measurements Contrast Mode provides seven generic measurement tools. Use these tools when you want to add measurements that aren't part of a measurement protocol.
Chapter 48: Analyzing Contrast Mode images 2. In the physiology data trace window below the image mode data, click to place the initial caliper. 3. Trackball to the location where you want to place your end caliper and then click to place the caliper. 4. If you need to move the entire measurement, click on a measurement line and then drag and drop it. Related information Complete procedure for adding a measurement (page 166) Traced distance measurement Traced distance is measured in mm.
Chapter 48: Analyzing Contrast Mode images Related information Complete procedure for adding a measurement (page 166) 2D Area measurement 2D Area is measured in mm2. f To place a 2D area measurement: 1. Click the 2D area measurement button . 2. Click on your image to place the initial caliper. 3. Trackball along the contour of your target tissue and then right-click to place your last caliper.
Chapter 48: Analyzing Contrast Mode images The mean and standard deviation values to the right of the histogram The blue indicator on the gray scale indicates the mean gray level. The green indicators on the gray scale indicate the standard deviation for the gray level. f To export an image of the histogram plot: 1. Click Export. 2. In the Presets Export window: a. In the browse window, browse to the directory location where you want to export the file and select that directory. b.
Chapter 48: Analyzing Contrast Mode images 2. Click on your image to place the initial caliper. This is the outside end of the first ray of your angle. 3. Trackball to where you want to position the vertex of your angle and then click to place the caliper. This completes the first ray. 4. Trackball to the position where you want to end the second ray and then click to place the final caliper.
Chapter 48: Analyzing Contrast Mode images Copying and pasting a contrast region f To copy and paste a region: 1. Right-click the contour and select Copy Region. 2. Right-click in another cine loop and click Paste Region. The copied region replaces the existing region. 3. On a cine loop that does not contain a contour, right click anywhere on the image and select Paste Contrast Region. The copied region is added to the loop, with its original coordinates.
Chapter 48: Analyzing Contrast Mode images 2. f The system calculates the contrast intensity within the boundaries of the region curve and displays the data in the Contrast Region Analysis window. To export the contrast region analysis: 1. Click Export. The Export Contrast Region window appears. 2. In the folder browser, browse to the location where you want to export your data and select the folder. 3.
Chapter 48: Analyzing Contrast Mode images Chart Y Axis Chart X Axis Calculation Use these controls to achieve different views of the contrast intensity data. Display Options Rev 1.1 Setting Description Draw Average Line Draws a moving average line through the data points. Frames Sets the number of frames over which to complete the average. Select from 2, 4, 8, 16, 32 Draw Markers Draws markers on the actual data points.
Chapter 48: Analyzing Contrast Mode images Setting Description Curve Fitting Calculates and plots a perfusion curve based on the following formula*: , where: y = Contrast signal (pixel intensity) A = Peak of curve B = Slope of the curve C = Contrast signal offset t = Time t0 = Time offset To create the curve: 1. Click Start Curve Fitting and select a data point on the graph at the transition from the base line to the perfusion period. 2.
Chapter 48: Analyzing Contrast Mode images Chart X Axis Setting Description Time Select to scale the length of the cine loop in second increments. Frame Number Select to scale the length of the cine loop in single frame increments. Calculation Setting Description Power Sets the Y axis to B-Mode mean power (linear a.u.) Amplitude Sets the Y axis to B-Mode mean amplitude (linear a.u.) Exporting Contrast Mode data f To export contrast region data: 1.
Chapter 48: Analyzing Contrast Mode images 5. Click on the boundary of the inner wall of the myocardium, add caliper points using the same procedure you used to create the outer wall contour, and then right-click to complete the inner wall contour. The system adds the measurement label on the image and adds the measurement to the Measured Values section at the bottom of the left panel. 6. f If you need to move the entire measurement, click on a measurement line and then drag and drop it.
Chapter 48: Analyzing Contrast Mode images Creating a cardiac region analysis chart The contrast region line graph plots the contrast intensity data of a contrast region over the course of a complete cine loop. f To chart the cardiac region data: 1. On the Contrast Mode image, right-click the contour or the image label and select Region Graph. 2. The system calculates the contrast intensity within the boundaries of the region curve and displays the data in the Cardiac Region Analysis window.
Chapter 48: Analyzing Contrast Mode images Display Options Setting Description Draw Average Draws a moving average line through the data points. Plot Frame Specify the frame to draw if the Draw Average check box is cleared. Chart Y Axis Setting Description Contrast Plots the contrast intensity information from the contrast data. B-Mode Plots the grayscale intensity data from the B-Mode image. Auto Scale View a system-calculated best-fit scale value.
Section 15 Appendixes This section includes the following reference content. In This Section Measurement package protocols.......................................................................................366 Troubleshooting ..................................................................................................................401 Descriptions of control panel controls..............................................................................406 Options and accessories ....................
Appendix A: Measurement package protocols Appendix A Measurement package protocols This appendix details the measurement and calculation definitions for each measurement package that is available with the Vevo 2100 Imaging System. In this appendix Abdominal Measurement Package ...................................................................................366 Cardiac Measurement Package .........................................................................................
Appendix A: Measurement package protocols CHA Diam Common hepatic artery diameter mm Linear B-Mode CHA Diam Common hepatic artery diameter mm Depth M-Mode RHA Vel Right hepatic artery velocity mm/s Velocity PW Doppler RHA Diam Right hepatic artery diameter mm Linear B-Mode RHA Diam Right hepatic artery diameter mm Depth M-Mode LHA Vel Left hepatic artery velocity mm/s Velocity PW Doppler LHA Diam Left hepatic artery diameter mm Linear B-Mode LHA Diam Left hepatic artery
Appendix A: Measurement package protocols Gallbladder protocol Measurement definitions Label Description Units Generic type Mode GB Sag Gallbladder sagittal length mm Linear B-Mode GB Trans Gallbladder transverse length mm Linear B-Mode GB Wall Thickness Gallbladder wall thickness mm Linear B-Mode CBD Common bile duct diameter mm Linear B-Mode Kidney protocol Measurement definitions Label Description Units Generic type Mode R Kidney Sag Right kidney sagittal length mm Lin
Appendix A: Measurement package protocols ICA PSV ICA peak systolic velocity mm/s Velocity PW Doppler CCA PSV CCA peak systolic velocity mm/s Velocity PW Doppler Calculation definitions Name Description Units Formula RRA-A RI Right renal artery to aorta resistive index none (RRA PSV – Ao PSV) / RRA PSV LRA-A RI Left renal artery to aorta resistive index none (LRA PSV – Ao PSV) / LRA PSV ICA-CCA RI ICA to CCA resistive index none (ICA PSV – CCA PSV) / ICA PSV RRA RI Right renal a
Appendix A: Measurement package protocols Pancreas protocol Measurement definitions Label Description Units Generic type Mode Pancreas Sag Pancreas sagittal length mm Linear B-Mode Pancreas Trans Pancreas transverse length mm Linear B-Mode Duct Pancreatic duct diameter mm Linear B-Mode Female Reproductive protocol Measurement definitions Label Description Units Generic type Mode Uterus Sag Uterus sagittal length mm Linear B-Mode Uterus Trans Uterus transverse length mm Li
Appendix A: Measurement package protocols LO Vein Diam Left ovarian vein diameter mm Depth M-Mode Mammary Gland protocol Measurement definitions Label Description Units Generic type Mode Cervical Diam Mammary glands mm Linear B-Mode Thoracic Diam Thoracic diameter mm Linear B-Mode Abdominal Diam Abdominal diameter mm Linear B-Mode Inguinal Diam Inguinal diameter mm Linear B-Mode Papilla Mammae Diam Papilla mammae diameter mm Linear B-Mode Male Reproductive protocol Measu
Appendix A: Measurement package protocols R Test Trans Right testicle transverse mm Linear B-Mode RTA Vel Right testicular artery velocity mm/s Velocity PW Doppler RTA Diam Right testicular artery diameter mm Linear B-Mode RTA Diam Right testicular artery diameter mm Depth M-Mode RTV Vel Right testicular vein velocity mm/s Velocity PW Doppler RTV Diam Right testicular vein diameter mm Linear B-Mode RTV Diam Right testicular vein diameter mm Depth M-Mode L Test Sag Left t
Appendix A: Measurement package protocols EF Ejection fraction % MLVArea B-Mode FS Fractional shortening % MLVArea B-Mode CO Cardiac output ml/min MLVArea B-Mode V LV trace – long axis volume µL MLVArea B-Mode RVID;d Right ventricular internal diameter (diastole) mm Depth M-Mode IVS;d IVS;d Inter ventricular septum (diastole) mm Depth M-Mode LVID;d IVS;d Inter ventricular septum (diastole) mm Length B-Mode LVID;d LVAW;d Left ventricular anterior wall (diastole) mm D
Appendix A: Measurement package protocols LV Mass Cor (M-Mode) LV mass corrected mg LV Mass (M-Mode) * 0.8 LV Mass Cor (B-Mode) LV mass corrected mg LV Mass (B-Mode)* 0.8 LV Mass AW (M-Mode) LV Mass AW Uncorrected mg 1.053 * ((LVID;d + LVPW;d + LVAW;d)3 – LVID;d3) LV Mass AW Cor (M-Mode) LV Mass AW corrected mg LV Mass AW (M-Mode) * 0.
Appendix A: Measurement package protocols %EF (B-Mode) LV ejection fraction % 100 * ((LV Vol;d – LV Vol;s) / LV Vol;d) %FS (M-Mode) LV fractional shortening % 100 * ((LVID;d – LVID;s) / LVID;d) %FS (B-Mode) LV fractional shortening % 100 * ((LVID;d – LVID;s) / LVID;d) LV Mass (M-Mode) LV mass uncorrected mg 1.053 * ((LVID;d + LVPW;d + IVS;d) – LVID;d ) LV Mass (B-Mode) LV mass uncorrected mg 1.
Appendix A: Measurement package protocols Calculation definitions Name Description Units Endocardial Volume; d Endocardial volume µl in diastole Endocardial Volume; s Endocardial volume µl in systole Endocardial Stroke Volume Stroke volume µl Endocardial %EF Percent ejection fraction % Endocardial %FAC Percent fractional area change % Endocardial Area Change Area change mm Endocardial Fractional Shortening Fractional shortening % Endocardial CO Cardiac output ml/min Formula Endoc
Appendix A: Measurement package protocols Label Description Units Generic type Mode Asc Ao Ascending aorta length mm Length B-Mode Trans Arch Transverse aortic arch diameter mm Length B-Mode Desc Ao Descending aorta diameter mm Length B-Mode Units Simpson's protocol Measurement definitions Label Simp Area Dist; d Simp Area Mid; d Description Simpson's area distal, diastole Simpson's area mid, diastole Generic type Mode 2 Area B-Mode 2 Area B-Mode 2 mm mm Simp Area Prox;
Appendix A: Measurement package protocols Volume/Flow protocol Measurement definitions Label Description Units Generic type Mode LVOT Left ventricular outflow tract length mm Length B-Mode LVOT VTI LVOT velocity time integral cm VTI PW Doppler Mean Vel LVOT mean velocity mm/s VTI PW Doppler Mean Grad LVOT mean pressure gradient mmHg VTI PW Doppler Peak Vel LVOT peak velocity mm/s VTI PW Doppler Peak Grad LVOT peak pressure gradient mmHg VTI PW Doppler Cycles LVOT cycles
Appendix A: Measurement package protocols Cycles Aorta cycles (none) VTI PW Doppler PV VTI Pulmonary velocity time integral cm VTI PW Doppler Mean Vel Pulmonary mean velocity mm/s VTI PW Doppler Mean Grad Pulmonary mean pressure gradient mmHg VTI PW Doppler Peak Vel Pulmonary peak velocity mm/s VTI PW Doppler Peak Grad Pulmonary peak pressure gradient mmHg VTI PW Doppler Cycles RVOT cycles (none) VTI PW Doppler AV Peak V Aortic valve peak velocity mm/s Vertical Velocit
Appendix A: Measurement package protocols Peak Vel LVOT peak velocity mm/s VTI PW Doppler Peak Grad LVOT peak pressure gradient mmHg VTI PW Doppler Cycles LVOT cycles (none) VTI PW Doppler AV Peak V Aortic valve peak velocity mm/s Vertical Velocity PW Doppler AoV VTI Aorta velocity time integral cm VTI PW Doppler Mean Vel Aorta mean velocity mm/s VTI PW Doppler Mean Grad Aorta mean pressure gradient mmHg VTI PW Doppler Peak Vel Aorta peak velocity mm/s VTI PW Doppler
Appendix A: Measurement package protocols MV Flow protocol Measurement definitions Label Description Units Generic type Mode MV VTI Mitral valve velocity time integral cm VTI PW Doppler Mean Vel Mitral valve mean velocity mm/s VTI PW Doppler Mean Grad Mitral valve mean pressure gradient mmHg VTI PW Doppler Peak Vel Mitral valve peak velocity mm/s VTI PW Doppler Peak Grad Mitral valve peak pressure gradient mmHg VTI PW Doppler Cycles Mitral valve cycles (none) VTI PW Doppl
Appendix A: Measurement package protocols MV A Mitral valve A velocity mm/s 2 Vertical Velocity PW Doppler Acceleration PW Doppler MV Decel E wave deceleration time mm/s T E wave deceleration time ms Time PW Doppler IVRT Isovolumic relaxation time ms Time PW Doppler IVCT Isovolumic contraction time ms Time PW Doppler MV ET Mitral valve ejection time ms Time PW Doppler NFT Non-filling time ms Time PW Doppler AET Aortic ejection Time ms Time PW Doppler Calculation defi
Appendix A: Measurement package protocols PV Flow protocol Measurement definitions Label Description Units Generic type Mode PV VTI Pulmonary velocity time integral cm VTI PW Doppler Mean Vel Pulmonary mean velocity mm/s VTI PW Doppler Mean Grad Pulmonary mean pressure gradient mmHg VTI PW Doppler Peak Vel Pulmonary peak velocity mm/s VTI PW Doppler Peak Grad Pulmonary aorta peak pressure gradient mmHg VTI PW Doppler Cycles Pulmonary aorta cycles (none) VTI PW Doppler PV
Appendix A: Measurement package protocols Tissue Doppler protocol Measurement definitions Label Description Units Generic type Mode MV E Mitral valve velocity at E mm/s Velocity PW Doppler E' Velocity at E' mm/s Velocity Tissue Doppler A' Velocity at A' mm/s Velocity Tissue Doppler IVRT Isovolumic relaxation time ms Time Tissue Doppler IVCT Isovolumic contraction time ms Time Tissue Doppler ET Ejection time ms Time Tissue Doppler TV LW E' Tricuspid valve velocity at E'
Appendix A: Measurement package protocols Label Description Units Generic type Mode TV VTI Tricuspid velocity time integral cm VTI PW Doppler Mean Vel Tricuspid mean velocity mm/s VTI PW Doppler Mean Grad Tricuspid mean pressure gradient mmHg VTI PW Doppler Peak Vel Tricuspid peak velocity mm/s VTI PW Doppler Peak Grad Peak pressure gradient mmHg VTI PW Doppler Cycles Tricuspid cycles (none) VTI PW Doppler TV E Tricuspid valve E wave velocity mm/s Vertical Velocity PW
Appendix A: Measurement package protocols UA Diam Umbilical artery diameter mm Depth M-Mode UV Vel Umbilical vein velocity mm/ms Velocity PW Doppler UV Diam Umbilical vein diameter mm Linear B-Mode UV Diam Umbilical vein diameter mm Linear M-Mode VA Vel Vitelline artery velocity mm/ms Velocity PW Doppler VA Diam Vitelline artery diameter mm Linear B-Mode VA Diam Vitelline artery diameter mm Depth M-Mode VV Vel Vitelline vein velocity mm/ms Velocity PW Doppler VV Diam
Appendix A: Measurement package protocols Choroid Thickness Choroid thickness mm Linear B-Mode Sclera Thickness Sclera thickness mm Linear B-Mode Retina Thickness Retina thickness mm Linear B-Mode Retinal Artery Velocity Retinal artery velocity mm/s Velocity PW Doppler Retinal Vein Velocity Retinal vein velocity mm/s Velocity PW Doppler Vascular Measurement Package This section provides the measurements and calculations information for the protocols in the Vascular measurement pack
Appendix A: Measurement package protocols SMA Diam;s Superior mesenteric artery diameter mm Linear B-Mode SMA Diam;d Superior mesenteric artery diameter mm Linear B-Mode SMA Diam;s Superior mesenteric artery diameter, systole mm Depth M-Mode SMA Diam;d Superior mesenteric artery diameter, diastole mm Depth M-Mode SMA VTI Superior mesenteric artery velocity time integral cm VTI PW Doppler Peak Vel Superior mesenteric artery peak velocity mm/s VTI PW Doppler Mean Vel Superior m
Appendix A: Measurement package protocols Carotid Arteries protocol Measurement definitions Label Description Units Generic type Mode LCCA PSV Left common carotid peak systolic velocity mm/s Velocity PW Doppler LCCA EDV Left common carotid end diastolic velocity mm/s Velocity PW Doppler LCCA Diam;s Left common carotid diameter, systole mm Linear B-Mode LCCA Diam;d Left common carotid diameter, diastole mm Linear B-Mode LCCA Diam;s Left common carotid diameter, systole mm Depth
Appendix A: Measurement package protocols LECA PSV Left external carotid peak systolic velocity mm/s Velocity PW Doppler LECA EDV Left external carotid end diastolic velocity mm/s Velocity PW Doppler LECA Diam;s Left external carotid diameter, systole mm Linear B-Mode LECA Diam;d Left external carotid diameter, diastole mm Linear B-Mode LECA Diam;s Left external carotid diameter, systole mm Depth M-Mode LECA Diam;d Left external carotid diameter, diastole mm Depth M-Mode LECA
Appendix A: Measurement package protocols LCCA PI Left common carotid pulsatility index none ((Left Common Carotid PSV - (Left Common Carotid EDV)/ (Left Common Carotid VTI,Mean Velocity RCCA RI Right common carotid resistive index none (Right Common Carotid PSV - Right Common Carotid EDV)/ Right Common Carotid PSV RCCA PI Right common carotid pulsatility index none (Right Common Carotid PSV - Right Common Carotid EDV)/ Right Common Carotid VTI,Mean Velocity LICA RI Left internal carotid resis
Appendix A: Measurement package protocols LSA Diam;d Left Subclavian artery diameter, diastole mm Linear B-Mode LSA Diam;s Left Subclavian artery diameter, systole mm Depth M-Mode LSA Diam;d Left Subclavian artery diameter, diastole mm Depth M-Mode LSA VTI Left Subclavian artery velocity time integral cm VTI PW Doppler Peak Vel Left Subclavian artery peak velocity mm/s VTI PW Doppler Mean Vel Left Subclavian artery mean velocity mm/s VTI PW Doppler Peak Grad Left Subclavian a
Appendix A: Measurement package protocols Iliac Arteries protocol Measurement definitions Label Description Units Generic type Mode CLI PSV Common left iliac artery peak systolic velocity mm/s Velocity PW Doppler CLI EDV Common left iliac artery end diastolic velocity mm/s Velocity PW Doppler CLI Diam;s Common left iliac artery diameter, systole r mm Linear B-Mode CLI Diam;d Common left iliac artery diameter, diastole mm Linear B-Mode CLI Diam;s Common left iliac artery diameter,
Appendix A: Measurement package protocols LEI PSV Left external iliac artery peak systolic velocity mm/s Velocity PW Doppler LEI EDV Left external iliac artery end diastolic velocity mm/s Velocity PW Doppler LEI Diam;s Left external iliac artery diameter, systole mm Linear B-Mode LEI Diam;d Left external iliac artery Diameter, diastole mm Linear B-Mode LEI Diam;s Left external iliac artery Diameter, systole mm Depth M-Mode LEI Diam;d Left external iliac artery Diameter, diastole
Appendix A: Measurement package protocols CLI PI Common left iliac artery pulsatility index none (Common Left Iliac Artery PSV - Common Left Iliac Artery EDV)/ Common Left Iliac Artery VTI, Mean Velocity CRI RI Common right iliac artery resistive index none (Common Right Iliac Artery PSV - Common Right Iliac Artery EDV)/ Common Right Iliac Artery PSV CRI PI Common right iliac artery pulsatility index none (Common Right Iliac Artery PSV - Common Right Iliac Artery EDV)/ Common Right Iliac Artery
Appendix A: Measurement package protocols RFA Diam;d Right femoral artery diameter, diastole mm Linear B-Mode RFA Diam;s Right femoral artery diameter, systole mm Depth M-Mode RFA Diam;d Right femoral artery diameter, diastole mm Depth M-Mode RFA VTI Right femoral artery velocity time integral cm VTI PW Doppler Peak Vel Right femoral artery peak velocity mm/s VTI PW Doppler Mean Vel Right femoral artery mean velocity mm/s VTI PW Doppler Peak Grad Right femoral artery peak gra
Appendix A: Measurement package protocols RSaA EDV Right saphenous artery end diastolic velocity mm/s Velocity PW Doppler RSaA Diam;s Right saphenous artery diameter, systole mm Linear B-Mode RSaA Diam;d Right saphenous artery diameter, diastole mm Linear B-Mode RSaA Diam;s Right saphenous artery diameter, systole mm Depth M-Mode RSaA Diam;d Right saphenous artery diameter, diastole mm Depth M-Mode RSaA VTI Right saphenous artery velocity time integral cm VTI PW Doppler Peak V
Appendix A: Measurement package protocols Mean Grad Left renal artery mean gradient mmHg VTI PW Doppler RRA PSV Right renal artery peak systolic velocity mm/s Velocity PW Doppler RRA EDV Right renal artery end diastolic velocity mm/s Velocity PW Doppler RRA Diam;s Right renal artery diameter, systole mm Linear B-Mode RRA Diam;d Right renal artery diameter, diastole mm Linear B-Mode RRA Diam;s Right renal artery diameter, systole mm Depth M-Mode RRA Diam;d Right renal artery d
Appendix A: Measurement package protocols Mean Vel Other artery mean velocity mm/s VTI PW Doppler Peak Grad Other artery peak gradient mmHg VTI PW Doppler Mean Grad Other artery mean gradient mmHg VTI PW Doppler Calculation definitions OA RI Other artery resistive index none (Other Artery PSV - Other Artery EDV)/ Other Artery PSV OA PI Other artery pulsatility index none (Other Artery PSV - Other Artery EDV)/ Other Artery VTI, Mean Velocity Umbilical Arteries protocol Measurement de
Appendix A: Measurement package protocols Calculation definitions Name Description Units Formula UT RI Uterine artery resistive index none (Uterine Artery PSV - Uterine Artery EDV)/ Uterine Artery PSV UM RI Umbilical artery resistive index none (Umbilical Artery PSV - Umbilical Artery EDV)/ Umbilical Artery PSV VIT RI Uterine artery resistive index none (Vitelline Artery PSV - Vitelline Artery EDV)/ Vitelline Artery PSV 400 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Appendix B: Troubleshooting Appendix B Troubleshooting If a problem is encountered when using the Vevo 2100 Imaging System, try the solutions described in this appendix. If none of the solutions solves the problem, contact a VisualSonics Technical Support representative (support@visualsonics.com). System panel controls Problem Solution System does not power up Ensure that the main power cable for the system is properly connected to the Vevo 2100 Imaging System.
Appendix B: Troubleshooting B-Mode Problem Solution Lack of penetration or sensitivity Ensure that there is adequate coupling medium (for example, ultrasound gel) between the transducer and the animal. Adjust the position of the TGC sliders. Increase the Transmit Power. Ensure the appropriate transducer is being used.
Appendix B: Troubleshooting Problem Solution Low frequency noise level in PW Doppler acquisition is high Noise appears in the image Increase the Wall Filter setting. Adjust the Sample Volume size and position such that it includes tissue only. 3D-Mode Problem Solution Can’t initialize the motor Ensure that the cable for the 3D motor stage is connected to the rear panel.
Appendix B: Troubleshooting Problem Solution Lack of penetration or sensitivity Increase the Transmit Power. Ensure that there is adequate coupling medium (for example, ultrasound gel) between the transducer and the animal. Adjust the position of the TGC sliders. Ensure the appropriate transducer is being used.
Appendix B: Troubleshooting Problem Solution Blood pressure signal is not accurate Calibrate the blood pressure signal. Check hardware gain and blood pressure check box in Operator Preferences. Check positioning and operation of blood pressure catheter. Measurements, annotations and calculations Problem Solution Measurement tools are not available Rev 1.1 Ensure that the system is not acquiring data or playing a cine loop. Ensure that data is displayed in the mode window.
Appendix C: Descriptions of control panel controls Appendix C Descriptions of control panel controls This appendix lists all available controls in alphabetical order and describes the function of each control. 2D Gain Adjusts the strength of the ultrasound signal when it returns to the face of the transducer. Range values for the control are specific to each individual transducer. Turn clockwise to add gain and brighten your entire image. Turn counterclockwise to reduce gain and darken your image.
Appendix C: Descriptions of control panel controls Press and hold FN while you tap this Down arrow key to decrease the keyboard backlighting brightness between the the series of seven brightness levels and the Off setting. Baseline Adjusts the vertical position of the horizontal zero frequency line (the baseline) that divides the image data coming toward the transducer face from the image data moving away from the transducer face. Push up to raise the line. Pull down to lower the line.
Appendix C: Descriptions of control panel controls Turn to adjust playback speed or move from frame to frame when in pause mode. When you review M-Mode, PW Doppler Mode and PW Tissue Doppler Mode data, turn to increase or decrease the sweep speed of the Doppler data. Cine Store In B-Mode, M-Mode, Contrast Mode, Color Doppler Mode and Power Doppler Mode: Stores a set of sequential frames. In PW Doppler Mode, PW Tissue Doppler Mode and M-Mode: Stores image data acquired over time.
Appendix C: Descriptions of control panel controls from the face of the transducer at which the system begins to display the ultrasound image. To use this rocker switch control: Pull down to remove a 1mm strip of image data from the top. For example, if your transducer is set to acquire data from 2mm to 12mm, when you pull the control down once, the display will only show the data between 3mm and 12mm. The minimum depth varies by transducer. Push up to add a 1mm strip of image data to the top.
Appendix C: Descriptions of control panel controls Active during: PW Doppler Mode, PW Tissue Doppler Mode, Color Doppler Mode, Power Doppler Mode image acquisition sessions. Dynamic Range Adjusts the input signal strength that is mapped into the spectral display. Range: 5-100dB. Push up to increase the range by 5dB and lower contrast. Higher dynamic ranges are often used in cardiac imaging. Pull down to decrease the range by 5dB and increase contrast.
Appendix C: Descriptions of control panel controls 2. Pull the rocker switch back to cycle back through the focal zone options in reverse. Focus Depth Adjusts the depth of the B-Mode focal zone or focal zones on your image. When you have more than one focal zone this control moves the depth of all the focal zones as a group. Push up to decrease the depth. Pull down to increase. Frame Rate Adjusts the acquisition frame rate. Turn clockwise to increase the frame rate.
Appendix C: Descriptions of control panel controls Image Label In the Study Browser: Adds a name to the image that is currently selected in the list. In a Mode window: Stores the current image and adds the name that you type in the box if the Auto SAVE on Image Label option is selected in the General tab of the Preferences window. Image Process Provides additional pre- and post-processing options for the active imaging Mode. Note: Not supported in the current release.
Appendix C: Descriptions of control panel controls Image Width Adjusts the physical width of the area the transducer is imaging. Push up to increase the width. Pull down to decrease the width. Tip: The closer you can reasonably narrow the width of your image around your target structure, the higher the system sets the acquisition frame rate. This is especially helpful when you are studying cardiac tissue movement. Invert Flips the image. In B-Mode: Press to flip the image left/right.
Appendix C: Descriptions of control panel controls M-Mode Activates M-Mode image acquisition. To use this key control: 1. Press to begin displaying the M-Mode sample volume overlay on the fullwindow B-Mode acquisition data. 2. Press M-Mode again (or press Update ) to display the live M-Mode data in the lower window and the live B-Mode data with the sample volume overlay data in the scout window. Mode Settings When in a Mode window, activates the mode settings panel.
Appendix C: Descriptions of control panel controls In Color Doppler Mode and Power Doppler Mode: Applies to the color signal data only. It does not apply to the B-Mode background data. Levels: Off, Low, Med, High, Max. Helpful when you are studying abdominal organ tissue such as liver, kidney and pancreas. In Contrast Mode: Sets the process persistence filter level. Levels: None, MIP. Physio Settings When in a Mode window, activates the physiological settings panel.
Appendix C: Descriptions of control panel controls Useful when you suspect, for example, that color data is covering over the actual contour of a vessel wall. In this case you would lower the priority until the overlay data matches the actual tissue contour and properties. PW Activates PW Doppler Mode acquisition.
Appendix C: Descriptions of control panel controls Sensitivity Adjusts the signal-to-noise ratio so that you can: Better identify weak-signal targets in the near field that are difficult to distinguish because they are very small Better identify large targets in the far field that are difficult to distinguish because the signal is so attenuated at depth. The higher you set the sensitivity level, the lower the system sets the frame rate. Push up to increase sensitivity. Pull down to decrease.
Appendix C: Descriptions of control panel controls SV/Gate Push up to increase. Pull back to decrease. In M-Mode: This control adjusts the size of the sample gate, measured in mm. The control adjusts the distance of the vertical line between the two yellow calipers. In the dual window view, the system displays the M-Mode sample gate image data. Current data is on the right side, trailing data extends to the left.
Appendix C: Descriptions of control panel controls some cases, if your imaging window is large and the Velocity is set high, the minimum speed may be greater. The system displays the updated values in the status bar in the lower left area of the screen. Active during: M-Mode, PW Doppler Mode and PW Tissue Doppler Mode image acquisition and review sessions. ----||---- Time gain compensation controls.
Appendix C: Descriptions of control panel controls Velocity Adjusts the PRF (pulse repetition frequency). The higher you set the PRF, the lower the signal resolution. In PW Doppler Mode: Adjust the range of the scale of the Y axis on the Power Doppler Mode image window by adjusting the pulse rate frequency of the ultrasound signal. Use this control when the spectral waveform is either too compressed or too expanded for your purposes.
Appendix C: Descriptions of control panel controls Zoom Activates a customizable blue zoom box overlay and magnifies the image data inside that box. To use this three-stage toggle control: Zoom 1. Press to activate the control and display the blue zoom box overlay. 2. Modify the proportion of the zoom box. a. Press Update . The system changes the box to a dashed-line box. b. Trackball left/right and up/down to change the width and height of the zoom box. c. Press Update to reapply the box. 3.
Appendix D: Options and accessories Appendix D Options and accessories This appendix lists the available options and accessories for the Vevo 2100 Imaging System.
Appendix D: Options and accessories Vevo 2100 Workstation Software VS-11962 Vevo 2100 Workstation System VS-11963 MicroMarker™ contrast agent and cannulation kits Item Part number Vevo MicroMarker™ Non-Targeted Contrast Agent Kit VS-11694 Vevo MicroMarker™ Target-Ready Contrast Agent Kit VS-11675 Vevo MicroMarker™ DEPO™ Contrast Agent Kit VS-11676 MicroMarker™ VA (Vascular Access) Cannulation Kit (1-pack) VS -11720 MicroMarker™ VA (Vascular Access) Cannulation Kit (3-pack) VS -11721 MicroMa
Appendix D: Options and accessories Thermasonic Gel Warmer (230V) SA-10750 Low Viscosity Ecogel (1 pk = 6 x 250mL) SA-11621 High Viscosity Aquasonic Gel (1 pk = 6 x 250mL) SA-11622 ECG Sigma Gel - Electrode gel (60g) SA-10740 Nair Hair Remover Cream SA-10747 Aquagel Lubricant SA-10738 T-Spray SA-10748 Power cords and plugs Item Part number Mains AC Power Cord – North America SA-11233 Mains AC Power Cord - Australia/New Zealand SA-11234 Mains AC Power Cord - Japan SA-11235 Mains AC Pow
Appendix D: Options and accessories Vevo Compact Dual Anesthesia System (Mobile Version) SA-12056 New orders must be shipped with 2 regulators of O2 and MA types Vevo Compact Medical Air Anesthesia System Conversion Kit (Tabletop Version) SA-11829 Vevo Compact Medical Air Anesthesia System Conversion Kit (Mobile Version) SA-11922 “H” Type Regulator SA-10414 “E” Type Regulator SA-10415 “H” Type Medical Air Regulator SA-11830 “E” Type Medical Air Regulator SA-11831 Single Yoke Assembly/Regulato
Appendix D: Options and accessories 2-Day On-Site MicroMarker™ Training VS-2D-MMTRAIN 1-Day On-Site MicroMarker™ Training VS-1D-MMTRAIN Additional 1-Day of On-Site User Training VS-ADD-1DTRAIN Customized 2-Day In Vivo User Training (Toronto) VS-INVIVOTRAIN 2-Day In Vivo Workshop (Toronto) VS-2D-WSHOP 1-Day In Vivo Workshop (Toronto) VS-1D-WSHOP 2-Day In Vivo Imaging Workshop (Amsterdam) VS-2D-WSHOP-EU 1-Day In Vivo Imaging Workshop (Amsterdam) VS-1D-WSHOP-EU Supplier VisualSonics Inc.
Appendix E: Product safety testing and electrical testing Appendix E Product safety testing and electrical testing VisualSonics products tested Vevo 2100 Imaging System VisualSonics MicroScan transducers: MS-200, MS-250, MS-400, MS-550D, MS-550S Tested to the following standards CISPR 11:1997/EN 55011:1998, CLASS A, GROUP 1 - Limits and methods of measurements of radio disturbance characteristics of industrial, scientific and medical (ISM) radio-frequency equipment.
Appendix E: Product safety testing and electrical testing Authorized representative Europe Atlantic Bridge Limited Zenith House 11 the Street Chirton Devizes Wiltshire SN10 3QS UK Tel: +44(0) 1380.848170 Contact: Mr. David Baker E-mail: david.baker@atlanticbridge.co.uk 428 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Appendix F: Safety Appendix F Safety Please read the safety information before using the Vevo 2100 Imaging System. The following information applies to the Vevo 2100 Imaging System and supporting equipment. The use of this equipment is intended for qualified research scientists. Read all warnings and cautionary notes carefully before you use this equipment.
Appendix F: Safety Electric shock hazards WARNING: Before connecting the Vevo 2100 to the mains, verify that the specified voltage on the rear panel matches the power source voltage. An incorrect power source voltage could cause an electrical hazard and could cause serious damage to the equipment. WARNING: Before connecting the Vevo 2100 to the mains, always check that the mains cable is undamaged. WARNING: Do not remove any panels from the Vevo 2100 Imaging System.
Appendix F: Safety WARNING: Disconnect the system from the power source before cleaning the system or performing any maintenance operations. WARNING: Connection of devices not authorized by VisualSonics to the Vevo 2100 Imaging System isolation transformer could result in an electrical hazard.
Appendix F: Safety Electromagnetic interference WARNING: The Vevo 2100 Imaging System should never be used where patient safety could be affected by the malfunction of medical devices. The Vevo 2100 Imaging System is designed for use in preclinical laboratories and is not cleared for use with or in the vicinity of active medical devices. High levels of electromagnetic energy may interfere with the operation of the Vevo 2100 Imaging System.
Appendix F: Safety CAUTION: Watch out for strained and twisted cables. Some of the optional accessories have long cables. Take care when working around the cables. CAUTION: VisualSonics recommends that the Vevo 2100 Imaging System be pushed by one person from behind and guided by another person in front, using the grab bars. Please use caution when going up or down ramps. Keep the system upright during transport.
Appendix F: Safety WARNING: Changes or modifications not expressly approved by VisualSonics could void the operator’s authority to operate the equipment. 434 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Appendix G: Specifications Appendix G Specifications Environmental specifications The Vevo 2100 Imaging System operating environment should be free of fumes, dirt, and electrical interference. Specification Value Temperature 10º to 40º C (50º to 104º F) Relative humidity 15% to 80% non-condensing Altitude Up to 2000m System dimensions Dimension Value Height (without monitor) 112 cm (44 in.) Height (with monitor) 155 cm (61 in.) Width 71 cm (28 in.) Depth 101 cm (39.5 in.
Appendix G: Specifications WARNING: Before having the system installed, ensure that the electrical service in the facility is adequate. Do not modify the attachment plug or use an adapter. Doing so may cause an electrical hazard. 436 VisualSonics Vevo 2100 Imaging System Operator Manual Rev 1.
Appendix H: Technical support and user maintenance Appendix H Technical support and user maintenance This appendix details the technical support and user maintenance information. Service provided by VisualSonics If problems arise with the Vevo 2100 Imaging System, VisualSonics will ensure that the system remains operational, with minimal downtime.
Appendix H: Technical support and user maintenance Maintaining the Vevo 2100 Imaging System The Vevo 2100 Imaging System requires proper care and cleaning. Improper system care voids the warranty or the service contract. Move the system carefully. Be especially alert when you move the system along inclined passages. Moving the system f Use the following precautions when you move the system: Turn the system off and disconnect the power cord and any other cords.
Appendix H: Technical support and user maintenance 3. f Replace the ball and the housing ring. To disinfect the system: Use Sporicidin wipes. Maintaining the MicroScan transducer The MicroScan transducer is the most delicate component of the Vevo 2100 Imaging System. Use care when handling the transducer. Proper handling maintains the high quality performance of the transducer in addition to extending the working lifetime of the transducer and the transducer.
Appendix H: Technical support and user maintenance Disposal The equipment owner is required to ensure that environmental and health and safety regulations are met when disposing of this equipment. Because the Vevo 2100 Imaging System includes components that may contain substances that could be harmful, particular care should be taken to meet the current regulations for the disposal of hazardous substances.
Appendix H: Technical support and user maintenance f To clean the air filter: 1. With a flat-head screwdriver turn the panel latch screw counter-clockwise until you loosen the panel from the frame. 2. Firmly but carefully lift the panel until the white tongues are out of the frame slots. 3. Carefully pull the panel straight back. 4. Twist off the filter housing lid thumbscrews and remove the filter housing lid. Filter Filter housing Panel latch Rev 1.1 5.
Appendix H: Technical support and user maintenance f To replace the air filter: 1. Slide the filter back into the filter housing. 2. Replace the filter housing lid and twist on the filter housing lid thumbscrews. 3. Carefully slide the panel tongues into the frame slots and then screw the pane latch screw back in until it is tight. Cleaning the frame base air filters Your system includes one air filter at the front of the frame base and an identical one at the rear.
Appendix I: Declaration of Conformity Appendix I Declaration of Conformity Rev 1.
Appendix I: Declaration of Conformity Glossary of Terms 3D-Mode 3D-Mode provides a threedimensional view of an area of interest. The system acquires the 3D data by creating a rapid series of BMode slices, then combining these slices into a whole image. You can then use the analysis tools to manipulate the three-dimensional renderings and make volumetric measurements of the structures you are interested in. Annotation A text label you can add to any ultrasound image.
Appendix I: Declaration of Conformity Targeted molecular imaging for visualizing and quantifying the expression of intravascular molecular markers — for example: angiogenesis and inflammation Tumor perfusion and relative quantification of vascular volume and structure Assessment of myocardial perfusion and area of infarction Electrocardiogram is a electronic representation of a physiological measurement of the electrical potentials of heart tissue. The output is a trace of the heart rhythm.
Appendix I: Declaration of Conformity MIP (Min) Minimum Intensity Persistence highlights the less dense portions of the volume by bringing them forward in the image and making them darker. This more clearly displays a small dark object in the middle of a bright ultrasound image. Operator A specified operator of the system with whom study sessions may be associated.
Appendix I: Declaration of Conformity excluding the image acquisition tools features. Rev 1.
Appendix I: Declaration of Conformity application packages • 36 applications • 91, 92 Index B 2 2D area measurement • 203 3 3D motor stage • 102, 103 3D-Mode acquisition setup • 102, 103, 282, 286 adding generic measurements • 301 control panel controls • 281 overview • 39, 272 recording • 286 rendering images • 291 rotating images • 290 sculpting • 293 troubleshooting • 403 typical acquisition session • 275 visualization tools • 288 volume measurements • 295, 296, 298, 300, 301 workspace • 275 A abdom
Appendix I: Declaration of Conformity contrast agents • 348 displaying as overlay • 348, 350 non-targeted • 348 targeted • 348 control panel controls • 345 overview • 39 troubleshooting • 404 typical acquisition session • 338 workspace • 343 contrast region measurement • 356, 357, 358 control panel • 23 control panel controls 3D-Mode • 281 backlighting control • 23, 406, 407 B-Mode • 194 Color Doppler Mode • 309 Contrast Mode • 345 descriptions • 406 M-Mode • 229 Power Doppler Mode • 327 PW Doppler Mode •
Appendix I: Declaration of Conformity acceleration measurement • 262 angle measurement • 204 B-Mode LV Area measurement • 205, 207 cardiac region measurement • 361, 363 contrast region measurement • 356, 357, 358 deleting • 174 depth interval measurement • 235 displaying • 84, 85 embryo • 172 exporting • 188, 361 heart rate measurement • 236 lens radius measurement • 210 linear distance measurement • 202 LV wall measurements • 205, 207, 213, 217, 218, 220, 221, 223, 237, 361, 363 M-Mode chain measurements
Appendix I: Declaration of Conformity applications • 92 cine loop size • 71 Contrast Mode • 74 General tab • 70 image export • 73 institution name • 70 Maintenance tab • 97 measurement packages • 14, 80, 84, 85 Measurement tab • 80 mode settings • 95 mode window/scout window sizes • 73 Operator tab • 79 physiological alarm levels • 77 physiological display • 75, 76, 77 physiological live display • 76 Presets tab • 91 PW Doppler Mode scale • 73 transducer • 91 workspace • 51 presets • 91 pressure-volume mea
Appendix I: Declaration of Conformity finding • 129 locking • 131 modifying • 129 passwords • 130 T technical support • 437 testing • 427 time interval measurement • 208, 267, 317 traced distance measurement • 203 transducer arrays applications • 91, 92 available models • 20, 101 cleaning and storing • 439 components • 19 connecting • 103, 106 description • 19 front ports • 21, 106 orienting for 3D-Mode • 286 preferences • 91 selecting • 101 storing • 102 troubleshooting • 401 turning on/off • 34 Vevo Im
