SDS
Quick-FDS [18133-12185-25785-010708] - 2017-08-23 - 03:23:06
Product:
FORANE® 404A
Page: 7 / 10
SDS No.: 001741-001 (Version 1.3) Date 22.08.2017 (Cancel and replace : 19.06.2017)
ARKEMA 420 rue d’Estienne d'Orves - 92700 Colombes – FRANCE
Absence of toxic effects for foetal development.
NOAEL ( Developmental Toxicity ): 50,000 ppm
NOAEL ( Maternal Toxicity ): 50,000 ppm
(Method: OECD Test Guideline 414, Rat, By inhalation)
Specific target organ toxicity :
Single exposure :
Inhalation: The substance or mixture is not classified as specific target organ toxicant, single exposure.
Repeated exposure:
The substance or mixture is not classified as specific target organ toxicant, repeated exposure.
1,1,1 TRIFLUOROETHANE :
Studies of prolonged inhalation in animals have not shown sub-chronic toxic effects
• In animals :
Inhalation: No specific toxic effects
NOAEL= 40000ppm (Method: OECD Test Guideline 413, Rat, 3 Months)
PENTAFLUOROETHANE :
• In animals :
Studies of prolonged inhalation in animals have not shown sub-chronic toxic effects
Inhalation: NOAEL= 50000ppm (Method: OECD Test Guideline 413, Rat, 3 Months)
1,1,1,2-TETRAFLUOROETHANE :
• In animals :
Inhalation: No adverse effects reported.
NOAEL= 50000ppm (Rat, Several years)
Aspiration hazard:
Not relevant
12. ECOLOGICAL INFORMATION
Ecotoxicology Assessment:
All available and relevant data on this product and/or the components quoted in section 3 and/or the
analogue substances/metabolites have been taken into account for the hazard assessment.
12.1. Acute toxicity :
Fish: According to its composition, can be considered as : Slightly harmful to fish
1,1,1 TRIFLUOROETHANE :
LC50 : 109 mg/l (Method: calculated)
PENTAFLUOROETHANE :
May be considered as comparable to a similar product for which experimental results are:
PROPANE, 1,1,1,3,3-PENTAFLUORO- :
LC50, 96 h (Danio rerio (zebra fish)) : > 200 mg/l (Method: OECD Test Guideline 203)
1,1,1,2-TETRAFLUOROETHANE :
LC50, 96 h (Salmo gairdneri) : 450 mg/l (Method: OECD Test Guideline 203)
Aquatic invertebrates: According to its composition, can be considered as : Slightly harmful to daphnia
1,1,1 TRIFLUOROETHANE :
EC50, 48 h (Daphnia magna (Water flea)) : 300 mg/l (Method: OECD Test Guideline 202)
PENTAFLUOROETHANE :
May be considered as comparable to a similar product for which experimental results are:
1,1,1,3,3-PENTAFLUOROBUTANE :
EC50, 48 h (Daphnia magna (Water flea)) : > 200 mg/l (Method: OECD Test Guideline 202)
1,1,1,2-TETRAFLUOROETHANE :
EC50, 48 h (Daphnia magna (Water flea)) : 980 mg/l (Method: OECD Test Guideline 202)
Aquatic plants: According to its composition, can be considered as : Slightly harmful to algae
1,1,1 TRIFLUOROETHANE :
May be considered as comparable to a similar product for which experimental results are:
1,1-DICHLORO-1-FLUOROETHANE :
EC50, 72 h (Pseudokirchneriella subcapitata) : > 44 mg/l (Method: OECD Test Guideline 201) No
effect up to the limit of solubility
PENTAFLUOROETHANE :
May be considered as comparable to a similar product for which experimental results are:
1,1,1,2-TETRAFLUOROETHANE :
May be considered as comparable to a similar product for which experimental results are:
PROPANE, 1,1,1,3,3-PENTAFLUORO- :
EC r50, 72 h (Pseudokirchneriella subcapitata) : > 118 mg/l (Method: OECD Test Guideline 201)
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