Technical data
28 Agilent 1290 Infinity LC System Manual and Quick Reference
2 The Agilent 1290 Infinity LC System - Product Description
System Components
The flow path of the pump has been optimized for minimal delay of gradients 
and incorporates an innovative mixing system using microfluidics technology. 
The mixing device, known as the Jet Weaver, employs a network of multi-layer 
microfluidic channels (120 µm x 120 µm) to unsure the flow is thoroughly 
mixed. The Jet Weaver has two standard volumes: 35 µl for normal UV 
detection applications and 100 µl for demanding situations such as the use of 
TFA in UV detection. For uncompromisingly low baseline noise in these 
demanding applications, a 380 µL Jet Weaver is also available. For MS 
detection it is often possible to work without the Jet Weaver and attain 
sufficient mixing using only the base 10 µl volume of the pump flow-path. 
Typical applications are high throughput methods with fast gradients on high 
resolution 2.1 mm columns.
The 1290 Infinity Binary pump comes ready for additional valve rails to be 
mounted on the right or left side of the pump. On these valve rails up to two 
additional 12-fold solvent selection valves can be attached. This allows a 
maximum of 26 solvents for binary gradients for analytical method 
development. A special “cluster driver” is available that makes the external 
solvent selection valves part of the pump user interface and allows very 
user-friendly and easy selection of the solvents by their names.










