Technical data

Agilent 1290 Infinity LC System Manual and Quick Reference 19
Introduction to Ultra-High Performance Liquid Chromatography
1
Frictional Heating
Figure 9 Influence of frictional heat generation on selectivity and effect of lowering
column temperature
In summary, the use of sub-two-micron packing material offers benefits of
increased efficiency, higher resolution and faster separations. The Agilent
1290 Infinity LC System and RRHD columns increase the separation space
available and enable more of these benefits to be accessed. The features of the
1290 Infinity LC are discussed in “The Agilent 1290 Infinity LC System -
Product Description” on page 21 and “Optimization of the Agilent 1290
Infinity LC System” on page 39considers how to apply the theory and use
these features to develop optimized separations.