SDS
Revision Date  22-Jan-2015 
Page 8 of 11 
Reproductive Toxicity 
Contains a known or suspected reproductive toxin 
STOT - single exposure 
No information available. 
STOT - repeated exposure 
Causes damage to organs through prolonged or repeated 
exposure. Based on classification criteria from the 2012 OSHA 
Hazard Communication Standard (29 CFR1910.1200), this product 
has been determined to cause systemic target organ toxicity from 
chronic or repeated exposure. (STOT RE). 
Chronic Toxicity 
No known effect based on information supplied. Contains a known 
or suspected carcinogen. Contains a known or suspected 
reproductive toxin. Possible risk of irreversible effects. Avoid 
repeated exposure. Prolonged exposure may cause chronic effects. 
May cause adverse effects on the bone marrow and blood-forming 
system. Repeated or prolonged skin contact may cause skin 
irritation and/or dermatitis and sensitization of susceptible persons.
May cause adverse liver effects. 
Target Organ Effects 
Respiratory system. Eyes. Skin. Gastrointestinal tract (GI). 
Reproductive System. Blood.Central Nervous System (CNS). 
Central Vascular System (CVS). Kidney. Lungs. Nasal cavities. 
Cardiovascular system. Systemic Toxicity. Liver. 
Aspiration Hazard 
No information available. 
Numerical measures of toxicity Product Information 
The following values are calculated based on chapter 3.1 of the GHS document 
ATEmix (oral) 
ATEmix (dermal) 
ATEmix (inhalation-dust/mist) 
Ecotoxicity 
Very toxic to aquatic life with long lasting effects. 
Chemical 
Name 
Toxicity to Algae  Toxicity to Fish  Toxicity to 
Microorganisms
Daphnia 
Magna (Water 
Flea) 
Nickel oxide
1313-99-1 
72h EC50: = 0.18 mg/L 
(Pseudokirchneriella 
subcapitata) 96h EC50: 
0.174 - 0.311 mg/L 
(Pseudokirchneriella 
subcapitata) 
96h LC50: > 100 mg/L 
(Brachydanio rerio) 96h 
LC50: = 1.3 mg/L (Cyprinus 
carpio) 96h LC50: = 10.4 
mg/L (Cyprinus carpio) 
48h EC50: > 100 
mg/L 
48h 
EC50: = 1 mg/L 
Copper 
7440-50-8 
96h EC50: 0.031 - 0.054
mg/L 
(Pseudokirchneriella 
subcapitata) 72h EC50: 
0.0426 - 0.0535 mg/L 
(Pseudokirchneriella 
subcapitata) 
96h LC50: 0.0068 - 0.0156 
mg/L (Pimephales promelas) 
96h LC50: = 0.112 mg/L 
(Poecilia reticulata) 96h 
LC50: = 0.3 mg/L (Cyprinus 
carpio) 96h LC50: = 0.8 
mg/L (Cyprinus carpio) 96h 
LC50: = 1.25 mg/L (Lepomis 
macrochirus) 96h LC50: = 
0.052 mg/L (Oncorhynchus 
mykiss) 96h LC50: = 0.2 
mg/L (Pimephales promelas) 
96h LC50: < 0.3 mg/L 
(Pimephales promelas) 
48h EC50: = 0.03 
mg/L 
Persistence and Degradability 
No information available. 
Bioaccumulation 
No information available 
Manganese dioxide 
1313-13-9 
<0 
12. ECOLOGICAL INFORMATION










