User Guide
Instruction manual
2
Requirements
•  M.2 NVMe SSD
•  Computer or server with a 2.5” SSD or HDD mounting bay 
•  Computer or server with an SFF-8643 port
•  SFF-8643 to SFF-8639 cable
•  Screwdriver
•  Pliers
This adapter is OS independent and doesn’t require any additional drivers or software.
Note: To determine if the drive and motherboard that you’re using are compatible, 
consult the technical specications that came with the drive and motherboard.
Requirements are subject to change. For the latest requirements, please visit 
www.StarTech.com/U2M2E125.
Connect an M.2 NVMe SSD
Warning! Drives should be handled carefully, especially when you transport them. If 
you’re not careful with your drives, you may experience lost or corrupted data. Make 
sure that you’re properly grounded by wearing an anti-static strap when you install 
any computer component. If an anti-static strap isn’t available, touch a large, grounded 
metal surface for several seconds to discharge any built-up static electricity.
1.  Depending on the length of the drive, you may need to move the preinstalled 
drive-mounting hardware. Place the drive next to the adapter and note the 
drive-mounting hole that matches the length of your drive. If the drive-mounting 
hardware is already installed in the correct position, proceed to step 4.
2.  Use a small pair of pliers to remove the nut from the reverse side of the converter.
3.  Place the nut and stando that you removed in the previous step in the drive-
mounting hole that matches the length of the drive, and use a screwdriver to 
tighten them.
4.  Gently slide the connector on the drive into the M.2 NVMe connector on the 
adapter.
5.  Insert the drive-mounting screw through the drive and into the stando, and use 
a screwdriver to tighten the drive-mounting screw.








