Use and Care Manual

Safety Data Sheet
Spectracide Pruning Seal
Page 10 of 17
September 9, 2020
2-Propanone LD50 (Rat): 5,580 mg/kg
Titanium oxide (TiO2) LD50 (Rat): >5,000 mg/kg
Quartz (SiO2) LD50: >5,000 mg/kg
DERMAL:
Product: Not classified for acute toxicity based on available data.
Specified substance(s):
Asphalt LD50 (Rabbit): >2,000 mg/kg
Benzene, methyl- LD50 (Rabbit): >5,000 mg/kg
Talc (Mg3H2(SiO3)4) LD50: >5,000 mg/kg
Kaolin LD50: 5,000 mg/kg
2-Propanone LD50 (Rabbit): 7,426 mg/kg
Titanium oxide (TiO2) LD50: >2,000 mg/kg
Quartz (SiO2) LD50: >5,000 mg/kg
INHALATION:
Product: Not classified for acute toxicity based on available data.
Specified substance(s):
Asphalt LC 50: > 20 mg/l
LC 50: > 5 mg/l
LC 50 (Rat): > 94.4 mg/m3
Benzene, methyl- LC 50 (Rat): 28.1 mg/l
LC 50: > 100 mg/l
Propane LC 50: > 100 mg/l
LC 50: > 100 mg/l
Butane LC 50: > 100 mg/l
LC 50: > 100 mg/l
Kaolin LC 50: > 100 mg/l
LC 50: > 100 mg/l
2-Propanone LC 50 (Rat): 50.1 mg/l
LC 50: > 5 mg/l
Titanium oxide (TiO2) LC 50 (Rat): > 6.82 mg/l
Quartz (SiO2) LD50: 5 mg/l
REPEATED DOSE TOXICITY:
Product: No data available.
Specified substance(s):
Asphalt
Benzene, methyl-
NOAEL (Rat(Female, Male), Inhalation, 28-50 d): 30mg/m3
Inhalation Read-across from supporting substance (structural
analogue or surrogate), Supporting study
NOAEL (Rat(Female, Male), Dermal, 28d): 200mg/kg Dermal
Experimental result, Key study
NOAEL (Rat(Female, Male), Dermal, 28d): 2,000mg/kg Dermal
Experimental result, Key study
LOEAL (Rat(Female, Male), Oral, 13 Weeks): 1,250 mg/kg (Target
Organ(s): Liver, Kidney) Oral Experimental result, Key study