User's Manual

62 – US-ENGLISH
At pre-discharge, a 24-hour Holter recording was performed and
pacemaker memory was read. At one month, pacemaker memory was
read. Investigators also documented adverse events.
Patients studied: A total of 45 patients from 12 centers had Symphony
2550 pacemakers with SafeR. Of these, 14 (31 %) were female and 31
(69 %) were male. Mean patient age (± SD) was 74 ± 9 years.
Primary indications for implant were: 1st degree AV block (11.1 %), 2nd
degree AV block (6.7 %), 3rd degree AV block (22.2 %), sinus node
dysfunction (62.2 %) or other (6.7 %).
Effectiveness results: To determine the effectiveness of SafeR mode,
the percentage of ventricular pacing provided over one month was
recorded from pacemaker memory.
Thirty-five patients contributed data to evaluate the percentage of ventricular
pacing provided with SafeR. Twenty-nine patients had 1 % or less
ventricular pacing and six patients had a range of 28-97 % ventricular
pacing. The graph below shows the distribution of ventricular pacing
observed in patients with and without AV block as a primary indication for
implant.