User's Manual

24 US-ENGLISH
Clinical Results V-V timing
V-V programmable settings were available for the clinical study devices as
follows: ALTO MSP model 617 (not programmable for V-V delay), ALTO 2
MSP model 627 values (0, 31, 39, 47, 55 and 63 ms) and OVATIO CRT-D
6750 values (0 to 63 ms in steps of 8 ms).
The graph below shows the programmed V-V settings at randomization
by percentage of patients programmed to each combination of
Synchronous BiV pacing and V-V delay.
RER at peak VO
2
at six months
0
10
20
30
40
50
60
≤ 0.79 0.80-0.89 0.90-0.99 1.0-1.09 1.10-1.19 1.20-1.29 ≥ 1.30
RER
Percent of patients
Test
Control
Programmed V-V Delays
Programmed settings for the 149 of 154 patients optimized
0
5
10
15
20
25
30
35
0 8 16 24 31 37 39 55 60 63
V-V Delay (msec)
% Patients
Synchronous BiV
Synchronous BiV (Left then Right)
Synchronous BiV (Right then Left)