User guide

2 Part # 11313539 Rev. B
iScan System Overview
Introduction
TheiScanSystemisaneasy‐to‐use,laser‐based,high‐resolutionbenchtopopticalimaging
systemthatcanrapidlyscanandcollectlargevolumesofdatafromIlluminaDNA
analysisandRNAanalysishigh‐densityBeadChips .
Withpowerfulscanningtoolsforgeneexpressionandgenotypingapplications,theiScan
Systemsupportsthe
rapid,sensitive,andaccurateimagingofallofIllumina’sBeadChip‐
basedgeneticanalysisproducts.Incorporatingthehighestperformanceopticsand
detectionsystems,theiScanSystemdeliversoutstandingdataqualityandreproducibility
whiledramaticallyreducingscantime.
BeadChipsaresubstratesusedformulti‐sampleanalysisinIlluminagenotypingandgene
expressionapplications.
AssayfeaturesareloadedintowellsofaBeadChiptocreatean
organizedarray.TheiScanSystemcompilesavirtualrepresentationofaBeadChip,
acquiresimagesoftheBeadChipfeatures,recordstheinformation,andexportsthedata
fordownstreamanalysisbyoneofIllumina’ssoftwareanalysistools.
NOTE
TheiScanSystemcanbeintegratedwithIlluminaLIMS(laboratory
informationmanagementsoftware)andassayautomationoptions,such
astheAutoLoader(AutoLoader2orAutoLoader2.xmodel),to
maximizethroughputtothousandsofsamplesperday.Whenusedwith
Infinium®HDBeadChipsandtheAutoLoader,theiScanSystemcan
reportupto
225milliongenotypesinasingleday,offeringthefastest
pathtodiscovery.