Basic Documentation
Table Of Contents
- Introduction
- Applicable Definitions (Alphabetical Listing)
- Laboratory Safety
- Hazard Assessment
- Chemical Hygiene Plan
- Chemical Hygiene Responsibilities
- Fume Hoods
- When Required & Safe Usage
- Gloveboxes:
- Face Velocity
- Face Velocity Setback
- Size & ADA Compliance
- CAV (Constant Air Volume) Bypass
- CAV (Constant Air Volume) Conventional
- VAV (Variable Air Volume)
- VAV Diversity
- Automatic Sash Closure
- Safe Operation of Sashes
- Accessories, Services and Explosion Protection
- Ductless
- Auxiliary Air
- (Special Purpose) Perchloric Acid
- Room Air Cross Currents
- Minimum Exhaust
- Monitoring
- Selection Criteria and Performance Specifications
- Laboratory Design & Fume Hood Implementation
- Maintenance
- Periodic Testing
- Test Procedures
- Signage and Recordkeeping
- Shutdown Procedures
- Evaluating CAV (Constant Air Volume) Systems
- Evaluating VAV (Variable Air Volume) Systems
- Biological Laboratories
- Biosafety Level 1
- Biosafety Level 2
- Biosafety Level 3
- Biosafety Level 4
- Ventilation for Biosafety Level 1
- Ventilation for Biosafety Level 2
- Ventilation for Biosafety Level 3
- Ventilation for Biosafety Level 4, Cabinet Laboratory
- Ventilation for Biosafety Level 4, Suit Laboratory
- Containment Levels - Canada
- Containment Levels and Ventilation Requirements: Canada
- Biological Safety Cabinets and Classifications
- Biosafety Cabinet Applications
- Biosafety Cabinets – Installation and Safe Usage Recommendations
- Biosafety Cabinets – Certification and Safe Usage - Canada
- Biological Safety Cabinet Design, Construction and Performance Requirements
- Biosafety Cabinet Testing
- Ventilation Systems
- Local Ventilation -When Required
- Ventilation Rates for Animal Rooms
- Ventilation Rates for Animal Rooms
- Ventilation Rates for Biological Labs
- Ventilation Rates for Chemical Laboratories
- Ventilation rates for Storage areas
- Room Supply Air
- Supply Air Quality and Filtration
- Room and Duct Pressurization
- Human Occupancy, Room Temperature and Humidity
- Animal Rooms Room Temperature and Humidity
- Load Calculations
- Room Sound Level and Vibration
- Emergency Control Provisions
- Energy Conservation
- Monitoring
- Maintenance
- Periodic Inspection and Testing
- Periodic Inspection and Testing - Canada
- Test Records
- Management
- Exhaust Systems
- Configuration
- Leakage
- Components
- Manifolded Systems
- Air Velocity
- Stack Height and Discharge Location
- Operational Reliability
- Recirculated Air and Cross Contamination
- Materials and Fire Protection
- Commissioning
- Commissioning - Canada
- Referenced Publications
Ventilation Systems
Siemens Industry, Inc. 103
Topic Requirement(s) Commentary
Supply Air
Quality and
Filtration
U.S. OSHA, 29 CFR, Part 1910, Occupational Safety and Health Standards,
Subpart Z, Toxic and Hazardous Substances,1910.1450,C1,D3:
The laboratory facility should have
(a) An appropriate general ventilation system with air intakes and exhausts located so
as to avoid intake of contaminated air.
Regular instrumental monitoring of airborne concentrations is not usually justified or
practical in laboratories but may be appropriate when testing or redesigning hoods or
other ventilation devices or when a highly toxic substance is stored or used regularly
(e.g., 3 times/week).
California OSHA – Division of Occupational Health & Safety (DOSH) Subchapter
7. General Industry Safety Orders, Group 16. Control of Hazardous Substances,
Article 107. Dusts, Fumes, Mists, Vapors and Gases
5143. General Requirements of Mechanical Ventilation Systems.
(d) Make-Up Air. Clean, fresh air, free of contamination from adjacent industrial
exhaust systems, chimneys, stacks, or vents, shall be supplied.
(1) The outside air supply shall enter the workroom in a manner which will not reduce
the effectiveness of any local exhaust systems.
(2) All seams and joints shall be sealed if negative pressure exists within inlet
ductwork such that there is a possibility of infiltration of harmful quantities of gases,
fumes, or mists from areas through which ductwork passes.
(3) Where the air supply is filtered, the filters shall be replaced or cleaned regularly to
prevent significant reductions in airflow. A pressure gauge shall be installed to show
the pressure drop across the filters. This gauge shall be marked to show the pressure
drop at which filters require cleaning or replacement.
(4) Where make-up air is heated by combustion, except gas, the products of
combustion shall not be mixed with the make-up air and shall be vented to a point
remote from all points where make-up air enters the building. For gas heating where
combustion products are mixed with the make-up air, the following must exist:
(A) The gas must be nontoxic and have a distinctive and strong enough odor to warn
workmen of its presence if unburned.
(B) The maximum rate of gas supply to the make-up air heater shall not yield in
excess of 2000 ppm of total combustible gas in the mixture upon flame failure.
(C) A fan shall be provided to remove the mixture of heated air and combustion
products from gas burner plenum chambers.
American Institute of Architects, GUIDELINES FOR PLANNING AND DESIGN OF
BIOMEDICAL RESEARCH LABORATORY FACILITIES 1999
C.7.5 c. Outdoor air intakes shall be located as far as practical (usually on
directionally different exposures) but not less than 9,000 mm (30’ 0”) from exhaust
outlets of combustion equipment stacks, cooling towers, ventilation exhaust outlets
from the building or adjoining buildings vacuum systems, plumbing vent stacks, or
areas that may collect vehicular exhaust and other noxious fumes. The bottom of
outdoor air intakes serving central systems shall be located as high as practical
above the roof or ground level.
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