SDS

Safety Data Sheet
LUPRANATEM20 ISO
Revision date : 2015/10/05
Page: 8/15
Version: 5.2
(30089687/SDS_GEN_US/EN)
not fire-propagating
Chemical stability
The product is stable if stored and handled as prescribed/indicated.
Possibility of hazardous reactions
Reacts with water, with formation of carbon dioxide. Risk of bursting. Reacts with alcohols. Reacts
with acids. Reacts with alkalies. Reacts with amines. Risk of exothermic reaction. Risk of
polymerization. Contact with certain rubbers and plastics can cause brittleness of the
substance/product with subsequent loss in strength.
Conditions to avoid
Avoid moisture.
Incompatible materials
acids, amines, alcohols, water, Alkalines, strong bases, Substances/products that react with
isocyanates.
Hazardous decomposition products
Decomposition products:
Hazardous decomposition products: carbon monoxide, carbon dioxide, nitrogen oxide, hydrogen
cyanide, nitrogen oxides, aromatic isocyanates, gases/vapours
Thermal decomposition:
No decomposition if stored and handled as prescribed/indicated.
11. Toxicological information
Primary routes of exposure
Routes of entry for solids and liquids are ingestion and inhalation, but may include eye or skin
contact. Routes of entry for gases include inhalation and eye contact. Skin contact may be a route
of entry for liquefied gases.
Acute Toxicity/Effects
Acute toxicity
Assessment of acute toxicity: Inhalation of vapours may cause irritation of the mucous membranes of
the nose, throat or trachea, breathlessness, chest discomfort, difficult breathing and reduced
pulmonary function. Inhalation exposure well above the PEL may result additionally in eye irritation,
headache, chemical bronchitis, asthma-like findings or pulmonary edema. Isocyanates have also
been reported to cause hypersensitivity pneumonitis, which is characterized by flu-like symptoms,
the onset of which may be delayed.
Oral
Information on: Diphenylmethane-4,4'-diisocyanate (MDI)
Type of value: LD50
Species: rat (male/female)
Value: > 2,000 mg/kg (Directive 84/449/EEC, B.1)
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Inhalation
Type of value: LC50
Species: rat (male/female)
Value: 2.0 mg/l (OECD Guideline 403)