MSDS

Monsanto Company, Lawn & Garden Products
Page: 6 / 9
Roundup® Ready-To-Use Extended Control
Weed & Grass Killer Plus Weed Preventer
Version: 1.0 Effective date: 04/21/2004
NOAEL toxicity: > 30 mg/kg body weight
NOAEL reproduction: > 30 mg/kg body weight
Target organs/systems in parents: none
Other effects in parents: none
Target organs/systems in pups: none
Other effects in pups: none
Developmental toxicity/teratogenicity
Rat, oral, 6 - 19 days of gestation:
NOAEL toxicity: 1,000 mg/kg body weight
NOAEL development: 1,000 mg/kg body weight
Other effects in mother animal: decrease of body weight gain, decrease of survival
Developmental effects: weight loss, post-implantation loss, delayed ossification
Effects on offspring only observed with maternal toxicity.
Rabbit, oral, 6 - 27 days of gestation:
NOAEL toxicity: 175 mg/kg body weight
NOAEL development: 175 mg/kg body weight
Target organs/systems in mother animal: none
Other effects in mother animal: decrease of survival
Developmental effects: none
Ammonium salt of imazapic
Mutagenicity
In vitro and in vivo mutagenicity test(s):
Not mutagenic.
Repeated dose toxicity
Rabbit, dermal, 21 days:
NOAEL toxicity: 1,000 mg/kg body weight/day
Target organs/systems: none
Rat, oral, 13 weeks:
NOAEL toxicity: 1,640 mg/kg body weight/day
Target organs/systems: none
Other effects: none
Carcinogenicity
Dog, oral, 1 years:
NOAEL toxicity: < 158 mg/kg body weight/day
Target organs/systems: skeletal muscle
Other effects: histopathologic effects, blood biochemistry effects
Rat, oral, 2 years:
NOEL tumour: 1,133 mg/kg body weight/day
NOAEL toxicity: 1,133 mg/kg body weight/day
Target organs/systems: none
Other effects: none
No tumours.
Mouse, oral, 18 months:
NOEL tumour: 1,288 mg/kg body weight/day
NOAEL toxicity: 1,288 mg/kg body weight/day
Target organs/systems: none
Other effects: none
No tumours.
Toxicity to reproduction/fertility
Rat, oral, 2 generations:
NOAEL toxicity: 1,344 mg/kg body weight/day
NOAEL reproduction: 1,344 mg/kg body weight/day
Target organs/systems in parents: none
Target organs/systems in pups: none