MSDS

Monsanto Company, Lawn & Garden Products Page: 7
Roundup® Weed & Grass Killer Concentrate Plus Version: 1.4 Effective date: 06/05/2002
Other effects in pups: decrease of body weight gain, decrease of litter survival
Effects on offspring only observed with maternal toxicity.
Developmental toxicity/teratogenicity
Rat, oral, 7 - 16 days of gestation:
NOEL toxicity: < 4 mg/kg body weight/day
NOEL development: 12 mg/kg body weight/day
Other effects in mother animal: decrease of body weight gain, decrease of food consumption
Developmental effects: weight loss, skeletal variations, visceral malformations, delayed ossification
Effects on offspring only observed with maternal toxicity.
Rabbit, oral, 7 - 19 days of gestation:
NOEL toxicity: 1 mg/kg body weight/day
NOEL development: 3 mg/kg body weight/day
Other effects in mother animal: decrease of body weight gain, decrease of food consumption
Developmental effects: visceral variations, delayed ossification
Effects on offspring only observed with maternal toxicity.
Mouse, oral, 6 - 15 days of gestation:
NOEL toxicity: 1 mg/kg body weight/day
NOEL development: 2 mg/kg body weight/day
Other effects in mother animal: decrease of body weight gain, breathing irregularities, neurotoxic signs, decrease
of survival
Developmental effects: weight loss, skeletal variations
Effects on offspring only observed with maternal toxicity.
Acute neurotoxicity
Rat, oral, single dose, gavage:
NOEL: 25 mg/kg body weight
Other effects: neuromuscular effects
Not neurotoxic.
Repeated dose neurotoxicity
Rat, oral, 14 weeks, dietary:
NOAEL: 8 mg/kg body weight/day
Target organs/systems : eyes
Other effects: decrease of body weight gain
Not neurotoxic.
12. ECOLOGICAL INFORMATION
This section is intended for use by ecotoxicologists and other environmental specialists.
Data obtained on similar products and on components are summarized below.
Similar formulation
Aquatic toxicity, fish
Rainbow trout (Oncorhynchus mykiss):
Acute toxicity, 96 hours, static, LC50: 5.4 mg/L
Moderately toxic.
Bluegill sunfish (Lepomis macrochirus):
Acute toxicity, 96 hours, static, LC50: 7.3 mg/L
Moderately toxic.
Aquatic toxicity, invertebrates
Water flea (Daphnia magna):
Acute toxicity, 48 hours, static, EC50: 11 mg/L
Slightly toxic.
Avian toxicity
Mallard duck (Anas platyrhynchos):
Dietary toxicity, 5 days, LC50: > 5,620 mg/kg diet