SDS

Monsanto Company, Lawn & Garden Products
Page: 6 / 10
Roundup® Weed & Grass Killer Concentrate Plus Version: 2.0 Effective date: 11/04/2015
Inhalation, short term: Not expected to produce significant adverse effects when recommended use instructions
are followed.
Single ingestion: Not expected to produce significant adverse effects when recommended use instructions are
followed.
Data obtained on product and components are summarized below.
Acute oral toxicity
Rat, female, LD50 (Method: Up-and-down procedure (OECD 425)): > 5,000 mg/kg body weight
Practically non-toxic. No mortality.
Acute dermal toxicity
Rat, LD50: > 5,000 mg/kg body weight
Practically non-toxic. No mortality.
Acute inhalation toxicity
Rat, LC50, 4 hours, aerosol: > 2.05 mg/L
Practically non-toxic. For purposes of the inhalation test, product was artificially aerosolized. Since this
material will not become aerosolized to a hazardous concentration during transport, it is classified as non-
hazardous under the transportation regulations in accordance with 2.6.2.2.4.7(b) and (c) of the UN
Recommendations on the Transport of Dangerous Goods. No mortality.
Skin irritation
Rabbit, 3 animals, OECD 404 test:
Days to heal: 3
Primary Irritation Index (PII): 0.5/8.0
Slight irritation.
Eye irritation
Rabbit, 3 animals, OECD 405 test:
Days to heal: 7
Moderate irritation.
Skin sensitization
Guinea pig, 3-induction Buehler test:
Positive incidence: 0 %
Negative.
N-(phosphonomethyl)glycine; { glyphosate acid}
Genotoxicity
Not genotoxic.
Carcinogenicity
Not carcinogenic in rats or mice. Listed as Category 2A by the International Agency for Research on Cancer
(IARC) but our expert opinion is that classification as a carcinogen is not warranted.
Reproductive/Developmental Toxicity
Developmental effects in rats and rabbits only in the presence of significant maternal toxicity.
Reproductive effects in rats only in the presence of significant maternal toxicity.
Diquat dibromide
Genotoxicity
Not genotoxic in vivo.
Carcinogenicity