MSDS

Monsanto Company, Lawn & Garden Products
Page: 5 / 10
Roundup® Concentrate Poison Ivy Plus Tough Brush Killer Version: 1.1 Effective date: 10/16/2009
Self-accelerating decomposition temperature (SADT)
No data.
11. TOXICOLOGICAL INFORMATION
This section is intended for use by toxicologists and other health professionals.
Acute oral toxicity
Rat, LD50 (limit test): > 5,000 mg/kg body weight
Practically non-toxic.
FIFRA category IV.
No mortality.
Acute dermal toxicity
Rat, LD50 (limit test): > 5,000 mg/kg body weight
Practically non-toxic.
FIFRA category IV.
No mortality.
Acute inhalation toxicity
Rat, LC50 (limit test), 4 hours, aerosol: > 2.95 mg/L
Practically non-toxic.
FIFRA category IV.
No mortality.
Skin irritation
Rabbit, 3 animals, OECD 404 test:
Days to heal: 3
Primary Irritation Index (PII): 0.7/8.0
Slight irritation.
FIFRA category IV.
Eye irritation
Rabbit, 3 animals, OECD 405 test:
Days to heal: 3
Moderate irritation.
FIFRA category III.
Skin sensitization
Guinea pig, 3-induction Buehler test:
Positive incidence: 0 %
N-(phosphonomethyl)glycine; {glyphosate}
Mutagenicity
In vitro and in vivo mutagenicity test(s):
Not mutagenic.
Repeated dose toxicity
Rabbit, dermal, 21 days:
NOAEL toxicity: > 5,000 mg/kg body weight/day
Target organs/systems: none
Other effects: none
Rat, oral, 3 months:
NOAEL toxicity: > 20,000 mg/kg diet
Target organs/systems: none
Other effects: none
Chronic effects/carcinogenicity
Mouse, oral, 24 months:
NOAEL toxicity: ~ 5,000 mg/kg diet
Target organs/systems: liver
Other effects: decrease of body weight gain, histopathologic effects