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Key values to detect and monitor CVD
Patients with CVD typically have high total cholesterol in their blood. The first step in both primary
and secondary preventative cholesterol-lowering therapy is assessment of the patient’s risk status.
8–10
Accutrend Plus – Test Parameters
Metabolic syndrome increases the risk of
developing CVD¹¹
Metabolic syndrome increases the risk of CVD and
type 2 diabetes. The worldwide prevalence is rising
due to increasing obesity and sedentary life styles.
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Metabolic syndrome is estimated to be present in 24%
of the US adult population
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and 15% for the same
group in Europe.
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Diagnostic criteria for metabolic syndrome (any 3 out
of 5 criteria constitute diagnosis):
• Triglycerides >_ 1.7 mmol/L (150 mg/dL)
• Fasting blood glucose >_ 5.55 mmol/L (100 mg/dL)
• Elevated waist circumference >_ 102 cm in men,
>_ 88 cm in women
• Blood pressure >_ 130/85 mm Hg
• Reduced HDL («good») cholesterol
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Values for serum total cholesterol
Total cholesterol mg/dL mmol/L
Desirable < 200 < 5.1
Borderline high 200–239 5.1–6.1
Very high > 240 > 6.2
Values for fasting serum triglycerides
Triglycerides mg/dL mmol/L
Normal < 150 < 1.69
Borderline high 150–199 1.69–2.24
High 200–499 2.25–5.61
Very high > 500 > 5.62
Fasting blood glucose
Blood glucose mg/dL mmol/L
Normal glucose tolerance 70–99 3.9–5.5
Impaired fasting glucose
(pre-diabetes) 100-125 5.6-6.9
Very high > 126** > 7.0**
Target values for fasting serum triglycerides
Triglycerides > 1.7 mmol/L (150 mg/dL)
are a sign of metabolic syndrome.
mg/dL mmol/L
Normal < 150 < 1.7
Target values for fasting blood glucose
mg/dL mmol/L
American College
of Endocrinology
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< 110 < 6.1
American Diabetic
Association
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90–130 5.0–7.2
Target values for total cholesterol levels
Once cholesterol targets are achieved
it is best to assess levels at least annually.
mg/dL mmol/L
Optimal 160 4.1
Audit standard* 200 5.1
* minimum standard of care for all
high-risk people
** on more than one testing occasion
Accutrend Plus
Test
Measuring Ranges
mg/dL mmol/L
Measuring Time Small Material Sample Volumes Operating Conditions
Glucose 20–600 1.1–33.3 12 sec Fresh capillary blood 15-50 μL 18°– 35°C
Cholesterol 150–300 3.88–7.76 180 sec
Fresh capillary blood
Use of heparin-coated
pipettes possible
15-40 μL 18°– 30°C
Triglycerides 70–600 0.80–6.86 max 174 sec
Fresh capillary blood
Use of heparin-coated
pipettes possible
10-40 μL 18°– 30°C
Lactate 0.8–22 mmol/L 60 sec
Fresh capillary blood
Use of heparin-coated
pipettes possible
15-50 μL 5°– 35° or 15°– 35°C
depending on con-
centration of analyte