Item Brochure

COBAS, LIFE NEEDS ANSWERS
and COMBUR-TEST are trademarks of Roche.
©2010 Roche
Roche Diagnostics Ltd.
CH-6343 Rotkreuz
Switzerland
www.roche.com
Combur-Test
®
strip technology
Specifications
Nylon mesh fixing of
components – unique
sealing technology
No interference with glue components
Avoidance of contamination by protective function
Uniform liquid penetration and color development
No run over of reaction color
Stable reaction colors
Synchronized reaction time
All in 60 seconds
Sturdy plastic carrier foil
No splashing of urine, hygienic strip reading
Absorbent paper
Iodate impregnated
component
Protects blood and glucose test areas efficiently from ascorbic acid interference and false-negative results
by oxidization even at high concentrations of vitamin C. When five common 10 parameter urine test strips
are compared, Combur-Test
®
strip showed the highest resistance to ascorbic acid interference at higher
hemoglobin or glucose concentrations
1
:
At a hemoglobin concentration of 0.075 mg/dL,
Combur-Test
®
strips were the only brand to register
a correct analysis with ascorbic acid levels as high
as 400 mg/L
1
At a glucose concentration of 300 mg/L, Combur-
Te st
®
strips were the only brand to show consistently
accurate results, even at an ascorbic acid level of
1000 mg/L
1
Additional diazonium salt
impregnated mesh
Improves reagent stability in the leukocyte test pad
Absorbent paper
Prevents chemical interference
Low test detection limits
High sensitivity and specificity
With no ascorbic acid present, only three out of five tests were able to detect pathologically relevant low
hemoglobin and glucose concentrations of 0.03 mg/dL and 50 mg/dL, respectively
1
Reliable visual evaluation
Colorfast printing colors on the label
Reading of all test pads at once at a consistent reading time
References
1. Nagel, D., Seiler, D., Hohenberger, E.F., Ziegler, M. (2006). Investigations of ascorbic acid interference in urine test strips. Clin Lab; 52:149-153.
Hemoglobin
(Target value of 0.075 mg/dL = 25 Ery/µL)
Ascorbic acid interference in routine analysis
Glucose
(Target value of 300 mg/dL)
Glucose [mg/dL]
Combur10 test
®
UX from Roche
Ascorbic acid [mg/L]Ascorbic acid [mg/L]
300
500
0
0 100 200 4000 100 200 400 1000
Combur 10
Other Brands
Combur 10
Other Brands Target value Target value
Combur10 test
®
UX from Roche
25
10
0
Hemoglobin [Ery/µL]