MSDS
MATERIAL SAFETY DATA SHEET RM43™ 43% Glyphosate Plus Weed Preventer
Page 4 of 6
10. STABILITY AND REACTIVITY
Chemical Stability: This material is stable under normal handling and storage conditions.
Conditions to Avoid: Excessive heat. Do not store near heat or flame.
Incompatible Materials: Strong oxidizing agents: bases and acids. This product reacts with galvanized
steel or unlined steel (except stainless steel) to produce hydrogen gas that may form a highly combustible
gas mixture which could flash or explode.
Hazardous Decomposition Products: Under fire conditions may produce gases such as hydrogen
chloride and oxides of carbon, nitrogen and phosphorous.
Hazardous Reactions: Hazardous polymerization will not occur.
11. TOXICOLOGICAL INFORMATION
Toxicological Data (Glyphosate):
Data from laboratory studies conducted on a similar, but not identical, Glyphosate formulation:
Oral: Rat
LD50:
>5,000 mg/kg
Dermal: Rabbit
LD50:
>5,000 mg/kg
Inhalation: Rat 4-hr
LC50:
>2.4 mg/l
Eye Irritation: Rabbit: Moderately to severely irritating.
Skin Irritation: Rabbit: Non-irritating
Skin Sensitization: Not a contact sensitizer in guinea pigs following repeated skin exposure.
Toxicological Data (Imazapyr):
Data from laboratory studies conducted on Imazapyr Technical:
Oral: Rat LD50: >5,000 mg/kg
Dermal: Rabbit LD50: >2,000 mg/kg
Inhalation: Rat 4-hr LC50: >1.3 mg/l
Eye Irritation: Rabbit: Severely irritating/corrosive
Skin Irritation: Rabbit: Slightly irritating
Skin Sensitization: Not a contact sensitizer in guinea pigs following repeated skin exposure.
Subchronic (Target Organ) Effects: Repeated overexposure to glyphosate may decrease body weight
gains and effects to liver. For imazapyr, no adverse effects at approximately 1,700 mg/kg/day (highest
dose tested).
Carcinogenicity / Chronic Health Effects: Prolonged overexposure to glyphosate may cause effects to
the liver. There was no evidence of carcinogenicity in animal studies using glyphosate. EPA has given
glyphosate a Group E classification (evidence of non-carcinogenicity in humans). Imazapyr did not cause
cancer in laboratory animals. EPA has classified imazapyr as a Group E (evidence of non-carcinogenicity
for humans) carcinogen.
Reproductive Toxicity: In laboratory animal studies with glyphosate, effects on reproduction have been
seen only at doses that produced significant toxicity to the parent animals. The results of animal studies
with imazapyr gave no indication of a fertility impairing effect.
Developmental Toxicity: In animal studies, glyphosate did not cause birth defects in animals; other
effects were seen in the fetus only at doses which caused toxic effects to the mother. No indications of a
developmental toxic / teratogenic effect were seen in animal studies with imazapyr.
Genotoxicity: Glyphosate has produced no genetic changes in a variety of standard in vitro (bacterial
cells) and in vivo tests using animals. For imazapyr, no mutagenic effect was found in various tests with
microorganisms and mammals.
Assessment Carcinogenicity: None listed with ACGIH, IARC, NTP or OSHA.
See Section 2: HAZARDS IDENTIFICATION for more information.