Product Manual

_________________________________________________________________________________
SofiaInfluenzaA+BFIA
  Page19of25
Analytical reactivity was further evaluated using a total of 12 influenza A viruses isolated from birds. The Sofia
InfluenzaA+BFIAdetectedallofthestrainsexamined(Table11).

Table11
AnalyticalReactivitywithDifferentIsolatesofAvianInfluenzaA
ViralStrain*
Viral
Type Sub‐Type
Minimum
Detectable
Level
(TCID
50
/mL)
A/Mallard/NY6750/78 A H2N2 100
A/Mallard/OH/338/86 A H4N8 50
A/Mallard/WI/34/75 A H5N2 100
A/Chicken/CA/431/00 A H6N2 50
A/Chicken/NJ/15086‐3/94 A H7N3 5
A/BlueWinged
Teal/LA/B174/86 A H8N4 10
A/Chicken/NJ/122210/97 A H9N2 10
A/Chicken/NJ/15906‐9/96 A H11N9 50
A/Duck/LA/188D/87 A H12N5 50
A/Gull/MD/704/77 A H13N6 0.625
A/Mallard/GurjevRussia/262/82 A H14N5 20
A/Shorebird/DE/172/2006 A H16N3 2
*The performance characteristics for influenza A virus subtypes emerging as
humanpathogenshavenotbeenestablished.

AnalyticalSpecificity
CrossReactivity
TheSofiaInfluenzaA+BFIAwasevaluatedwithatotalof18bacterialandfungalmicroorganismsand16non‐
influenzaviralisolates.Bacterialandfungalisolateswereevaluatedataconcentrationof2x10
6
cfu/mL.Viral
isolateswereevaluatedataconcentrationof2x10
5
TCID
50
/mL.Noneoftheorganismsornon‐influenzaviruses
listedbelowinTable12showedanysignofcrossreactivityintheassay.Flowofthesampleandappearanceof
theControlLinewerealsonotaffected.