SDS

Rat Dermal LD50: >2000 mg/kg

Eye Irritation (rabbit): Slightly irritant

Dermal Inhalation (rabbit): Not irritant

Skin corrosion/irritation: Not irritant

Dermal sensitization: Not a sensitizer

Chronic Toxicity: Repeated skin contact may cause dermatitis. Repeated oral intake of bromides (>9 mg/kg body

weight/day) may affect the central nervous system. Warning symptoms include mental dullness, slurred speech,

weakened memory, apathy, anorexia, constipation, drowsiness and loss of sensitivity to touch and pain.

Mutagenicity: Does not include DNA repair in cultured human epithelioid cells. Not clastogenic in human

lymphocytes metaphase analysis. Not mutagenic by the Ames Test.

Carcinogenicity: Not classified by IARC. Not included in NTP 12

Report on Carcinogens

Reproductive toxicity: Sodium bromide has been shown to cause embryo-fetal toxicity and malformations in rats

at dose levels which also produce maternal toxicity. The No-Oberved Effect Level (NOEL) is 100 mg/kg/day, and

the Acceptable Daily Intake (ADI) for sodium bromide for food and drinking water in humans is 1 mg/kg/day.

Comparable high doses of sodium chloride (table salt) similarly cause malformations, embryo-fetal toxicity, and

maternal toxicity in mice.

Teratogenicity: In the oral gavage pre-natal developmental toxicity study in the Rabbit, there were no obvious

effects of maternal treatment on the survival growth or development of the offspring at any of the dosages

investigated. The No Observes Effect Level (NOEL) for the developing conceptus was considered to be 250

mg/kg/day.

12. Ecological Information

Environmental fate: NaBr is an inorganic salt, which fully dissociates in aquatic environment to bromide and

sodium ions. It also undergoes degradation in soil to bromide ion (no further degradation or biodegradation will

occur)

Aquatic Toxicity:

96 – hour LC50, Fish: >1000 mg/l (rainbow trout)

>1000 mg/l (bluegill sunfish)

48 – hour EC50, Daphnia magna: >1000 mg/l

Avian Toxicity:

Oral LD50, Bobwhite quail: >2250 mg/kg

Dietary LC 50, Mallard Duck: >5633 ppm

Dietary LC50, Bobwhite quail: >5633 ppm

Toxicity to micro-organisms: Activated sewage sludge respiration inhibition test: EC50>1000 mg/l (3 hours):

NOEC was 1000 mg/l (3 hours)

Bioaccumulative potential: Not expected to bioaccumulate

Germany, water endangering classes (WGK): 1

13. Disposal Considerations

Waste Disposal: When this product is discarded or disposed of, as purchased, it is neither a characteristic nor a

listed hazardous waste according to US Federal RCRA regulations (40 CFR 261). As a non-hazardous waste, the

material may be disposed of in a landfill in accordance with government regulations; check local or state