SDS

Guardian Chlorinating Granules (47%) Page 6
Hazardous Decomposition Products: Chlorine
Decomposition Temperature: 170
o
C – 180
o
C
11. TOXICOLOGICAL INFORMATION
Component Animal Toxicology:
Oral LD50 Value:
Calcium Hypochlorite LD50 (65% calcium hypochlorite) 850 mg/kg Rat
Sodium Chloride: LD50 = 3,000 mg/kg Rat
Calcium Chloride: LD50 = 1,000 mg/kg Rat
Calcium Hydroxide: LD50 = 7,340 mg/kg Rat
Component Animal Toxicology:
Dermal LD50 Value:
Calcium Hypochlorite: LD50 (65% calcium hypochlorite) >2,000 mg/kg Rabbit
Sodium Chloride: LD50 > 10,000 mg/kg Rabbit
Calcium Chloride: LD50 = 2,630 mg/kg Rat
Calcium Hydroxide: No Data
Component Animal Toxicology:
Inhalation LC50 Value:
Calcium Hypochlorite: Inhalation LC50 1 h (65% calcium hypochlorite), (Nose Only) = 2.04 mg/l
Rat
Calcium Hypochlorite: Inhalation LC50 4 h (65% calcium hypochlorite), (Nose Only) = 0.51 mg/l
Rat
Sodium Chloride: Inhalation LC50 1 h > 42 mg/l Rat
Calcium Chloride: No Data
Calcium Hydroxide: No Data
Product Animal Toxicity:
Oral LD50 Value: LD50 Approximately 1,200 mg/kg Rat
Dermal LD50 Value: LD50 > 2,000 mg/kg Rabbit
Inhalation LC50 Value: LC50 1 h (Nose Only) > 2.04 mg/l Rat LC50 4 h (Nose Only) > 0.51 mg/l
Rat
Skin Irritation: Dry material causes moderate skin irritation. Wet material causes skin burns.
Eye Irritation: Corrosive to eyes.
Skin Sensitization: This material is not known or reported to be a skin or respiratory sensitizer.
Acute Toxicity: This product is corrosive to all tissues contacted and upon inhalation, may cause
irritation to mucous membranes and respiratory tract. The dry material is irritating to the skin.
However, when wet, it will produce burns to the skin.
Subchronic/Chronic Toxicity: There are no known or reported effects from repeated exposure
except those secondary to burns.
Reproductive and Developmental Toxicity: Calcium hypochlorite has been tested for teratogenicity in
laboratory animals. Results of this study have shown that calcium hypochlorite is not a teratogen.
Calcium Chloride: Not know or reported to cause reproductive or developmental toxicity.
Mutagenicity: Calcium hypochlorite has been tested in the Dominant lethal assay in male mice,
and it did not induce a dominant lethal response. Calcium hypochlorite has been reported to produce
mutagenic activity in two in vitro assays. It has, however, been shown to lack the capability to
produce mutations in animals based on results from the micronucleus assay. In vitro assays
frequently are inappropriate to judge the mutagenic potential of bactericidal chemicals due to a high
degree of cellular toxicity. The concentration which produces mutations in these in vitro assays is