Owners manual

Drug
conc.
(Cut-off
ranoe)
n
AMP
MTD
TI.IC
BZO
o%
cut-otf 30 30
0 30 0 30 0
30 0
-50%
Cut-off
30 30
0
3U
0
30 o 30
(,)
-25"/o
Cut-off 30
3
25 5 27 3
'25
5
Cut-ofr 30 15 15 15
13
+'15"/o
Gut-ofi 30 7
23
23
5
25
20
+50%
cut-off 30 o
30
o
30 0
30 o 30
+300Yo
Cut-ofi
30
0 30 0 30
0 30
0
30
(PERFORMANCE
CHARACTERISTICSI
,
.
Analytical
Sensitivity
A
Phosphate-buffered
saline
(PBS)
pool
was
spiked
with drugs to
target concentrations
of t
50% cut-otf,
*. 25o/o
eut-off
and
+300o/o
cut-off and tested
with the Multi-Drug
Rapid Test
Midstream. The
results are summarized below.
Acetaminophen
N-Acetylprocainamide
Aminopyrine
Ampicillin
Apomorphine
Atropine
Benzoic acid
d/l-Brompheniramine
Chloral-hydrate
Chlorothiazide
Chlorpromazine
Cholesterol
Cortisone
Creatinine
Dextromethorphan
Diflunisal
Diphenhydramine
p-Estradiol
Ethyl
-p-ami
nobenzoate
Erythromycin
Furosemide
Hemoglobin
Hydrochlorothiazide
o-Hydroxyhi
ppuric
acid
lbuprofen
dfl-lsoproterenol
Acetophenetidin
Acetylsalicylic acid
Arnoxicillin
l-Ascorbic acid
Aspartame
Benzilic acid
Benzphetamine
Caffeine
Chloramphenicol
(BIBLIOGRAPHYI
tzil"
d/l-Chloropheni ra
mi ne
Chloroquine
Clonidine
l-Cotinine
Deoxycorticosterone
Diclofenac
Digoxin
l-V-Ephedrine
Estrone-3-sulfate
l(-)-Epinephrine
Fenoprofen
Gentisic
acid
Hydralazine
Hydrocortisone
p-Hydroxytyramine
lproniazid
lsoxsuprine
Ketamine
Labetalol
Meperidine
Methylphenidate
Naproxen
Nifedipine
d-Norpropoxyphene
d/l-Octopamine
Oxolinic
acid
Papaverine
Pentazocine hydrochloride
Phenelzine
Phenylpropanolamine
Prednisone
d-Propoxyphene
Quinacrine
Quindine
Salicylic acid
Sulfamethazine
Tetracycline
Tetrahydrocortisone
3
(B-D-glucuronide)
Thioridazine
Tolbutamide
Trifluoperazine
d/l-Tryptophan
Uric
acid
Ketoprofen
Loperamide
Meprobamate
Nalidixic acid
Niacinamide
Norethindrone
Noscapine
Oxalic
acid
Oxymetazoline
Penicillin-G
Perphenazine
Trans-2-phenylcyclopropyla
mi
ne
hydrochloride
Prednisolone
d/l-Propranolol
d-Pseudoephedrine
Quinine
Ranitidine
Serotonin
Sulindac
Tetra hydrocorti
sone
3-acetate
Thiamine
d/l-Tyrosine
Triamterene
Trimethoprim
Tyramine
Verapamil
Zomepirac
Number:
145149103
Effective dates:201
5-
1
2-03
1. Mo_olchao, E., et al,
"Saliva
and
Plasma Testing for
Drugs of
Abuse:
Comparison of
the
Disposition and
Pharmacological
Effects of Cocaine", Addiction
Research
Center,
lRP,
NIDA,
NlH,
Baltimore, MD. As
presented
at
the
SOFT-TIAFT
meeting
October
1998.
2.
Kim, l,
et
al,
"Plasma and oral
fluid
pharmacokinetics
and
pharmacodynamics
after
oral
codeine administration", Clin
Chem, 2002
Sept,;48
(9), pp
1a86-96.
3.
Schramm,
W.
et
al,
"Drugs
of
Abuse in
Saliva:
A Review," J Anal
Tox, 1992
Jan-Feb;
16
(1).
pp
1-9
4. McCarron,
MM,
et
al,
"Detection
of
Phencyclidine
Usage
by
Radioirnmunoassay
of\
$aliva,"
J
Anal
Tox.
1984
Sep-Oct.; I
(5),
pp
197-201.
A
study
was conducted
to determine the cross-reactivity of the test with compounds spiked
into
drug-free
PBS
stock.
The following
compounds
demonstrated no lalse
positive
results
on the
Multi-Drug Rapid Test
Midstream
when
tested
with
at
concentrations
up
to 100
urug conc.
(Cut-off
ranoe)
n
PCP
COC
oPl
+
hstr
0% Cut-off
30 30
0
30 0 30
0
30
-tfl.:'
-5O%
Cut-off 30 30 t)
30
0
30 o
30
o
5% Cut-ofl 30
25
5
zt
27
3 26
4
cut-oft 30
14
16 15
15
b7o UUt-Of
30 10 2A
I 22
23 3 27
+5O7o
Cut-ofi 30 o 30
o 30
o
30 0
30
+SUUYo
UUt-Ofl
30 30
0
30
0
30 0
30
results
at a read time of 10 minutes.
]ompound
lng/mL
\MPFTETAMTNE
(AMF)
i,Amph-etami
J/l-Amphetamine
o0
25.000
ryptamrne
2.500
r-Hvdroxvamohetamine
00
,
+
)3,4-Metnyenedtoxyamphetamlne
(MIJA]
00
-Amphetamine
l5,u0u
2,500
I/IETHAMPHETAMINE
(MET)
)netamrne
,o
enfluramine
i0.000
lhetamine
rc0
Vlethoxvphenamine
t.000
)nentermrne
,500
,,4-Memylenedtoxymethampheta mt ne
(MUMA)
50
-Phenvleohrine
(R):(:)-Phenvlebhiihe
z5u
2rocaine
,000
K,ZU)
-
(-)
hpneoflne
100
:ohedrine 100
lenzphetamlne
25,000
UIARIJUANA
(THGI
1-nor-A"
-THC-g
COOH
50
lannabinol i0,000
IHU
C.UUU
IHU
U,UUU
1-nor-A1THC-g
COQH
r0
ligsAtNE
(s.!,L;t
_
locaine
t0
lene l0
:COOnlne
.500
icoonine methvl ester
2,500
CPIATES
(OPI
)ntne
to
lodeine
t5
=thylmorphine
Z5
)hlne
00
drocodone 00
)hanol 100
f,xycodone 25,000
,hr
ne
J-[5-U-Glucurontoe
t0
lorcodeine
.250
\ormorphine 25,000
rhine
0.090
Jxymorphone
25,000
hebaine
.0ul