User's Manual

PROOF DIAGNOSTICS COVID-19 TEST SYSTEM
24 25
Interfering Substances
The Proof Diagnostics COVID-19 Test was evaluated for performance in
the presence of potentially interfering substances that might be present in
a respiratory specimen. Negative specimens were evaluated in triplicate
to conrm that the substances were not cross-reactive with the test.
Specimens containing SARS-CoV-2 at a concentration near the limit of
detection were also evaluated in the presence of the substances in triplicate
to conrm that SARS-CoV-2 could still be detected. Results of the study
are below.
INTERFERING
SUBSTANCE
ACTIVE
INGREDIENT
CONCENTRA-
TION
SARS-COV-2
DETECTED
(CROSS-
REACTIVITY)
SARS-COV-2
DETECTED
(INTERFERING
SUBSTANCE)
Blood (whole) Blood 4% TBD TBD
Puried mucin
protein
Mucin 0.5% TBD TBD
Chloraseptic Benzocaine,
Menthol
1.5 mg/mL TBD TBD
Naso GEL
(NeilMed)
Naso GEL 5% v/v TBD TBD
Nasal Drops Phenylephrine 15% v/v TBD TBD
Afrin nasal spray Oxymetazoline 15% v/v TBD TBD
Nasal spray Cromolyn 15% v/v TBD TBD
Zicam Cold Rem-
edy
Galphimia
glauca, Luffa
operculate,
Sabadilla
5% v/v TBD TBD
Homeopathic
(Alkalol)
Alkalol 1:10 dilution TBD TBD
Sore throat
phenol spray
Phenol 15% v/v TBD TBD
Tobramycin Tobramycin 4 µg/mL TBD TBD
Mupirocin Mupirocin 10 mg/mL TBD TBD
Flonase Fluticasone 5% v/v TBD TBD
Tamiu Oseltamivir 5 mg/mL TBD TBD
Proof Lab Reader Maintenance
Cleaning the Reader
• Disconnect the Proof Lab from the main power outlet before
cleaning. Do not attempt to clean inside the cartridge insertion slot.
• Do not immerse the Proof Lab in liquid.
• Only wipe the external surfaces of the Proof Lab using the
recommended cleaning agents.
• Always ensure that proper laboratory procedures are followed
when handling and disposing of potentially hazardous material.
The following cleaning steps can be performed when necessary.
1. Make sure that no Test Cartridge has been left in the Proof Lab.
2. Disconnect the Proof Lab power cord from the main power outlet.
3. Use a soft cloth with 70% isopropyl alcohol solution or 0.6% bleach
solution to clean the outside surface of the Proof Lab.
4. Allow the Proof Lab to air dry.
Updating Firmware
When Proof Lab rmware updates become available, they can
be downloaded and installed using the Proof Diagnostics Update
Application for tablets and mobile devices.