Certifications 2

MSDS-No.: 430371
V002.0
Ponal Fix & Fest
Page 6 of 9
Serious eye damage/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
1,2-Benzisothiazol-3(2H)-
one
2634-33-5
highly irritating
48 h
rabbit
EPA OPP 81-4 (Acute Eye
Irritation)
Respiratory or skin sensitization:
Hazardous components
CAS-No.
Result
Test type
Species
Method
1,2-Benzisothiazol-3(2H)-
one
2634-33-5
sensitising
Mouse
local
lymphnod
e assay
(LLNA)
guinea pig
Magnusson and Kligman
Method
1,2-Benzisothiazol-3(2H)-
one
2634-33-5
sensitising
Mouse
local
lymphnod
e assay
(LLNA)
mouse
OECD Guideline 429 (Skin
Sensitisation: Local Lymph
Node Assay)
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
1,2-Benzisothiazol-3(2H)-
one
2634-33-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
1,2-Benzisothiazol-3(2H)-
one
2634-33-5
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
negative
oral: unspecified
rat
OECD Guideline 486
(Unscheduled DNA Synthesis
(UDS) Test with Mammalian
Liver Cells in vivo)
Repeated dose toxicity
Hazardous components
CAS-No.
Result
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
1,2-Benzisothiazol-3(2H)-
one
2634-33-5
NOAEL=10 mg/kg
oral: gavage
90 daysdaily
rat
OECD Guideline 408
(Repeated Dose 90-Day Oral
Toxicity in Rodents)
SECTION 12: Ecological information
General ecological information:
The mixture is classified based on the available hazard information for the ingredients as defined in the classification criteria for
mixtures for each hazard class or differentiation in Annex I to Regulation (EC) No 1272/2008. Relevant available
health/ecological information for the substances listed under Section 3 is provided in the following.
Do not empty into drains, soil or bodies of water.