Safety data sheet

MSDS-No.: 433400
V001.0
Pattex Haus & Bau Silicon - alle Farben
Page 12 of 15
Reproductive toxicity:
Hazardous substances
CAS-No.
Result / Classification
Species
Exposure
time
Species
Method
Trimethoxyvinylsilane
2768-02-7
NOAEL P = 250 mg/kg
one-
generation
study
oral: gavage
rat
OECD Combined Repeated
Dose and Reproductive /
Developmental Toxicity
Screening Test (Precursor
Protocol of GL 422)
NOAEL P = 1.000 mg/kg
one-
generation
study
oral: gavage
rat
OECD Combined Repeated
Dose and Reproductive /
Developmental Toxicity
Screening Test (Precursor
Protocol of GL 422)
NOAEL F1 = 1.000 mg/kg
one-
generation
study
oral: gavage
rat
OECD Combined Repeated
Dose and Reproductive /
Developmental Toxicity
Screening Test (Precursor
Protocol of GL 422)
Methanol
67-56-1
NOAEL P = 1,3 mg/l
NOAEL F1 = 0,13 mg/l
NOAEL F2 = 0,13 mg/l
Two
generation
study
inhalation
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
Repeated dose toxicity
Hazardous components
CAS-No.
Result
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Siloxanes and Silicones,
di-Me
63148-62-9
NOAEL=> 100000
ppm
oral: feed
28 d
rat
not specified
Siloxanes and Silicones,
di-Me
63148-62-9
NOAEL=> 1.000
mg/kg
dermal
29 d
rabbit
not specified
Trimethoxyvinylsilane
2768-02-7
NOAEL=< 62,5
mg/kg
oral: gavage
daily
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction / Developmental
Toxicity Screening Test)
Trimethoxyvinylsilane
2768-02-7
inhalation:
vapour
5 days/week for 14
weeks6 hours/day
rat
Methanol
67-56-1
NOAEL=6,63 mg/l
inhalation
4 weeks6 h/d, 5 d/w
rat
not specified
SECTION 12: Ecological information
General ecological information:
The mixture is classified based on the available hazard information for the ingredients as defined in the classification criteria for
mixtures for each hazard class or differentiation in Annex I to Regulation (EC) No 1272/2008. Relevant available
health/ecological information for the substances listed under Section 3 is provided in the following.
Do not empty into drains, soil or bodies of water.