Certifications 2

SDS No.: 433400 V003.0
Pattex Haus & Bau Silicon - alle Farben
Page 17 of 24
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Barium sulfate
7727-43-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Barium sulfate
7727-43-7
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Barium sulfate
7727-43-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
methanol
67-56-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
methanol
67-56-1
negative
in vitro mammalian
cell micronucleus
test
without
not specified
methanol
67-56-1
negative
mammalian cell
gene mutation assay
with and without
equivalent or similar to OECD
Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Trimethoxyvinylsilane
2768-02-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Trimethoxyvinylsilane
2768-02-7
positive
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Trimethoxyvinylsilane
2768-02-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Titanium dioxide
13463-67-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Titanium dioxide
13463-67-7
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Titanium dioxide
13463-67-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
octamethylcyclotetrasilox
ane
556-67-2
negative
bacterial gene
mutation assay
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
octamethylcyclotetrasilox
ane
556-67-2
negative
in vitro mammalian
chromosome
aberration test
with and without
equivalent or similar to OECD
Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
octamethylcyclotetrasilox
ane
556-67-2
negative
mammalian cell
gene mutation assay
with and without
equivalent or similar to OECD
Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
methanol
67-56-1
negative
intraperitoneal
mouse
equivalent or similar to OECD
Guideline 474 (Mammalian
Erythrocyte Micronucleus
Test)
Trimethoxyvinylsilane
2768-02-7
negative
intraperitoneal
mouse
other guideline:
Titanium dioxide
13463-67-7
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
octamethylcyclotetrasilox
ane
556-67-2
negative
inhalation
rat
equivalent or similar to OECD
Guideline 475 (Mammalian
Bone Marrow Chromosome
Aberration Test)
octamethylcyclotetrasilox
ane
556-67-2
negative
oral: gavage
rat
equivalent or similar to OECD
Guideline 478 (Genetic
Toxicology: Rodent Dominant
Lethal Test)