Product Manual

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Portable Cryosurgical System
Histofreezer
®
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Treatment Procedure
1. Have the patient lie face down
on an exam table, exposing the
plantar surface upward.
See Figure 1.
• Draw a circle around the
outermost edge of the plantar
wart(s) to be treated and
measure. Recording the size of
the lesion will help you
determine the response of the
wart site during subsequent
visits.
See Helpful Hint #1
2. Debride the wart to pinpoint
bleeding. We suggest using a
hemostatic solution to stop the
bleeding. Do not use silver nitrate
to stop the bleeding, as it will
cause irritation.
See Figure 2.
3 Insert the applicator into the
canister valve with a twisting
motion, and then remove the
protective cap from the upright
canister.
Hold the canister and applicator
away from skin and press the
dispensing valve until the first
droplet emerges from the foam tip,
then release finger from valve.
The droplets will not harm clothing
or office furnishings.
See Figure 3.
 Keep finger off the valve and
turn the canister, so the
applicator is in a vertical
position (90-degree angle).
Then wait 15 seconds for the
applicator to reach its
effective temperature.
See Figure 4.
 Continue to hold canister
in the same position and with
light pressure, place the
applicator on the treatment
area for the recommended time
listed on the canister label or
Directions for Use. Treating
at any other angle than a
90-degree angle will reduce the
effectiveness of the treatment.
See Figures 5a & 5b.
Important: Do not press valve while
the Histofreezer applicator is in
contact with patient’s skin.
• A saturated 2mm applicator will stay cold for 90 seconds
and the 5mm applicator will stay cold for 120 seconds.
This is long enough to perform 1 to 2 applications on the
same patient.
• After first use, lift applicator from contact with skin and
hold it in a vertical position again (90-degree angle), then
wait for 15 seconds for it to return to the treatment
temperature. Now it is ready to apply to the next “like”
wart or section of lesion.
NOTE:
The applicator supplied with the Histofreezer
®
Portable
Cryosurgical System kit freezes 2mm or 5mm across.
Lesions larger than the diameter of the applicator will
require treatment in sections.
See Helpful Hint #2
7. For treatment on a weight-bearing area, we suggest
applying an aperture pad or disbursement dressing for the
patient’s comfort. It is not advisable to occlude the treated
area with any keratolytic agent or vesicant for 24 hours. The
wart site may shrink or rise up however, a vesicular bullous
reaction should not occur.
4
15
SEC.
5a
5b
8. See Helpful Hint #2 for recommendations on adjunct
therapy with salicylic acid.
9. Schedule the patient for a return visit in two weeks.
This gives the treated area time to slough. Most plantar
warts will resolve within four treatments, at two–week
intervals. At each subsequent visit, perform the entire
procedure again.
Helpful Hints:
1. Always oversize the treatment. If the lesion is 5mm in size,
freeze 6mm to break the viral/normal skin barrier. You must
treat the entire wart, not just the center.
2. Resolution may occur in one to four treatments on warts
of 5mm or less without any adjunct therapy. For lesions
over 5mm in diameter, we suggest that the patient apply
a 17% salicylic acid preparation twice daily, beginning
24 hours after treatment with Histofreezer Portable
Cryosurgical System, continuing until the next visit. Before
treating the lesion with salicylic acid, protect the skin area
around it by applying petroleum jelly with a cotton tip.
See reverse side for main
Directions for Use
Check with your medical supplier for available Histofreezer
product configurations.
For additional information,
call toll-free 1-800-869-3538 or visit
www.histofreezer.com
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Recommended Freezing Times
Approximate Number of
Type of Lesion Freezing Time Treatments
Acrochordon (Skin Tags) ..................................................................................... 40 seconds
Actinic Keratosis (Facial)..................................................................................... 15 seconds
Actinic Keratosis (Non-Facial) ............................................................................. 40 seconds
Condyloma Acuminata (Genital Warts)................................................................. 40 seconds 1 to 4,
Lentigo (Facial)................................................................................................... 15 seconds at an interval
Lentigo (Non-Facial)............................................................................................ 40 seconds of 2 weeks.
Molluscum Contagiosum .................................................................................... 20 seconds
Seborrheic Keratosis........................................................................................... 40 seconds
Verruca Plana (Flat Warts)................................................................................... 20 seconds
Verruca Plantaris (Plantar Warts)......................................................................... 40 seconds
Verruca Vulgaris (Common Warts) ....................................................................... 40 seconds
Dependent on the nature and extent of the lesion, and the thickness of the skin, the treatment time can be adapted appropriately. Contact with
skin for more than 40 seconds may lead to deep freezing with damage to the dermis, and possibly scarring and/or nerve damage. It is advisable
to treat only one side of fingers and toes at a time to avoid freezing arteries or veins.