NEXT>>>ADVANCE www.nextadvance.com SP1600/SP1800 Programmable Syringe Pump Infusion Rate 60 50 40 30 20 10 0 0 10 20 30 40 50 60 70 80 90 Time WARNING NOT FOR CLINICAL USE ON HUMANS Publication #1200-02 Revision 1 V3.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump Quick Start Instructions Assumes that the pump was not previous programmed with a multiple Phase Pumping Program. Plug in the pump. Press the power switch to turn on power. Press any key to stop the display from blinking. Setup Pumping Parameters To Change Numbers: Use the arrow keys to increment individual digits. To move the decimal point: Press and hold the left-most arrow key for at least 1 second.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Table of Contents 1. General Information ...........................................................................................................1 Warnings 1.2 Disclaimer ....................................................................................................................................1 1.3 Warranty ..............................................................................................................
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 6.2 Start/Stop Triggers ...................................................................................................................13 6.3 Operating the Pump .................................................................................................................13 6.4 Changing the Pumping Rate and Direction While Pumping ................................................13 6.5 Volume Dispensed...................
NEXT>>>ADVANCE 8.4.5 8.4.6 8.4.7 8.4.8 9. Example 5: Example 6: Example 7: Example 8: www.nextadvance.com SP1600/1800 Programmable Syringe Pump Control from a High-Low Pressure Sensor ................................................................... 28 Automated Dispensing with Synchronization ............................................................... 29 Sub-Programs ................................................................................................................
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 1. General Information Thank you for purchasing the SP1600/SP1800 Programmable Multi-Syringe Pump. With the SP1600/SP1800 syringe pump you will be able to perform simple infusions or implement a complex automated dispensing system. Please familiarize yourself with the SP1600/SP1800's operation by reading this user's manual. For future reference, record the serial number, located on the rear of the pump, and the date of purchase.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 1.3 Warranty Next Advance, Inc. warranties this product, and accessories for a period of two years, parts and labor, from the date of purchase. The repaired unit will be covered for the period of the remainder of the original warranty or 90 days, whichever is greater. A return authorization number must be obtained from Next Advance before returning a unit for repair.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 2.1 Glossary of Terminology and Concepts When a device has as many features as the SP1600/SP1800, understanding its operation could be a daunting task at first. By understanding the key concepts and terminology used in this manual, the operation of the SP1600/SP1800 will become quite intuitive. Every effort has been made to design the SP1600/SP1800 with a consistent and intuitive user interface.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Terminology Momentary Press: A quick press, less then 1 second, then release of a key on the keypad. Display Blink: A momentary blanking of the LCD display. This indicates that the new data entered by the user is valid and has taken affect. Program Entry Mode: The mode where the Program Phase and Program function are selected and modified.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 3. Setup Place the pump on a stable surface. Plug the round connector end of the supplied power supply adapter into the power plug located on the lower right of the pump's rear. See section 10, Logic Interface: TTL Input and Output, for a diagram of the rear of the pump. Plug the other end of the power supply adapter into an appropriate electrical outlet.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump 5. User Interface Volume Dispensed Units Pumping Direction Motor Indicators Indicator Operating Indicator RS-232 Indicator mm ml l Dispensed min Withdraw hr Pumping Rate Volume Diameter Start Program Phase # Program Function Setup Stop Pumping Direction Key Program Entry Functions Figure 1: Front Panel 5.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Pumping Program will resume at the point where the Pumping Program was interrupted. When not lit (not blinking) the pump is stopped, but the Pumping Program may be operating a pause Phase. Starting the pump, when the Pumping Program is stopped, will start the Pumping Program from the beginning (Phase 1). ‘Withdraw’ indicates that the pumping direction is set for withdrawing.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 5.5 ‘Diameter’ and ‘Setup’ Key The ‘Diameter’ key allows the syringe inside diameter to be viewed and set. While being displayed, the ‘mm’ LED is lit. With the Pumping Program stopped, momentarily pressing this key will display the current diameter setting. Pressing the arrow keys will change the current diameter (see sec. 5.4, Arrow and Decimal Point Key). The ‘mm’ LED will blink while the diameter is being changed.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump With the Pumping Program stopped, and the “Volume to be Dispensed” displayed, pressing the arrow keys will change the “Volume to be Dispensed” (see sec. 5.4, Arrow and Decimal Point Key). The units of the volume are set according to the syringe diameter. The new “Volume to be Dispensed” is stored in the current Program Phase. If the “Volume to be Dispensed” is disabled, pressing any arrow key will change the display to 0.0.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 5.10 ‘Program Phase #’ (Number) Key When in the “Program Entry Mode”, momentary presses of the ’Program Phase #’ and the ‘Program Function’ keys switch between the Program Phase number and the Program Function displays. The Program Phase number will be displayed as number.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 5.13 Special Power-Up Functions The following special functions are accessed by pressing the relevant key, while turning on power to the pump. 5.13.1 Firmware Version Display To display the pump’s firmware version, press the left-most arrow key (/) while turning on power to the pump. The display will show: key will clear the display. n.n , where ‘n.n’ is the firmware version number. Pressing any 5.13.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump A communications time-out alarm occurred with an attached computer while operating in the “Safe Communications Mode”. This most likely indicates that the RS-232 cable was detached or the communication program on the computer has ended without turning off “Safe Communications Mode”. n An error was detected during power up, where ‘n’ indicates the error.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump 6. Operation Before the pump can be operated, the pumping data must be setup. At minimum, the syringe inside diameter and a non-zero pumping rate needs to be set. The operation of the pump can then be started from the keypad, TTL I/O connector, or from RS-232 control. From the keypad, pressing the ‘Start / Stop’ key will start the pump operation. 6.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump in the current Program Phase. Also changing the pumping direction changes the accumulated “Volume Dispensed” according to the new pumping direction. 6.5 Volume Dispensed While pumping, the display will show the total accumulated volume pumped with the ‘ml’ or ‘l’ LED lit and the ‘Dispensed’ LED lit. Volume is computed based upon the syringe inside diameter setting. The volume is accumulated separately for infusion and withdrawal.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump Display TTL I/O external connector settings. Press any arrow key to display. If TTL is selected, the following will be displayed: aa Operational Trigger setting. ‘aa’ is current setting. aa Directional control setting. 'aa' is current setting. n n n 'Pump Motor Operating' TTL output pin configuration. 'n' is the current setting. *** The "Lockout Disable Key" needs to be inserted to display this setting.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump 7.2 Audible Alarm Enable n Setting: ‘0’ = Disabled, ‘1’ = Enabled. When alarms are enabled, the buzzer will be sounded as follows: Condition Buzzer Action Pumping Program ended Continuous beeping Pumping Program paused for start trigger Continuous beeping Alarm condition, such as pump motor stalled Steady alarm Pressing any key, will stop the alarm. 7.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 7.6 Keypad Lockout n Setting: '0' = Disabled, '1' = Enabled. *** The "Lockout Disable Key" needs to be inserted into the TTL I/O connector to display this setting*** When enabled, the "Lockout Disable Key" needs to be inserted in the TTL I/O connector to change any of the pump's settings. When the key is removed, the user can only start or stop the pump and review current settings. Settings can still be changed from RS-232.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump The Reciprocating Pump Program sets the pump for use with a second pump, plus cable Part# CBL-DUAL, to create a continuous infusion system. Phase 1 Function RATE Rate 500 ml/hr Volume 10.0 ml Direction Infuse Phase 2 Function RATE Rate 500 ml/hr Volume 10.0 ml Direction Withdraw Phase 3 ." Function JP:01 7.8 Keypad Beep Enable n Setting: ‘0’ = Disabled, ‘1’ = Enabled.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 8. Pumping Program A Pumping Program is simply a pre-defined sequence of actions, or functions, which guarantees consistent and precise operation of the pump, automatically and with or without any user intervention. A Pumping Program can be as simple as continuous pumping at a fixed infusion rate.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump When the Pumping Program is started, with the ‘Start / Stop’ key, TTL I/O input, or RS-232 command, the Pumping Program will begin operating from Phase 1. Very complex dispensing Programs can be created with the Program functions available. Section 8.3 contains a detailed description of all the functions. 8.1.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump Also, a Pumping Program can be uploaded to an attached computer, which could then store it and produce a printout of the Pumping Program. 8.3 Program Function Descriptions 8.3.1 ‘rAtE’: Rate Function Defines a pumping function with a fixed pumping rate. This function defines a pumping setup consisting of the pumping rate, optional “Volume to be Dispensed”, and pumping direction.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Pumping Program continues execution at the Program Phase with the selected Pumping Program Selection Label. The pump searches for the selected Pumping Program Selection Label starting with the current Phase and continuing to the end of the Pumping Program memory, then from Phase 1 until the current Phase is reached again.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump as nesting of loops, with each loop being one nested layer for the duration of the loops pairing. Loops can be nested for a total of 3 layers deep. Loops can only be nested within the scope of an outer loop. 8.3.11 Pause Pumping If ‘nn’ is non-zero, the Pumping Program will pause pumping (stops pumping) for ‘nn’ seconds.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump 8.3.14 'ES:nn': Setup Event Square Wave Trigger Jump Phase nn The 'Event Square Wave' function operates the same as the 'ET' 'Event' function, with the exception of the triggering conditions. This function will trigger on either the rising or the falling edge of the TTL 'Event Trigger' input (pin 4). Therefore, a square wave function on the inupt pin can be used to toggle the pump between 2 sections of a Pumping Program.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 8.4.2 Example 2: Repeated Dispenses with Suck Back Dispense 2.0 ml with a 5 minute pause between dispenses. In addition, after each dispense, a volume of 0.25 ml is sucked back to prevent dripping. Also, 30 seconds before the end of the pause interval, a beep is sounded to alert the operator to prepare for the next dispense. Starting with the second dispense, 0.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 8.4.3 Example 3: Ramping the Flow Rate Continuously ramp up and down the pumping rate. Starting at 200 ml/hr, the pumping rate will increment to 250 ml/hr in 1.0 ml/hr steps after every 0.1 ml has been dispensed. Then the pumping rate will decrement to 150 ml/hr in 1.0 ml/hr steps after every 0.1 ml has been dispensed. Finally, the pumping rate is incremented back to 200 ml/hr in 1.0 ml/hr steps after every 0.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 8.4.4 Example 4: Complex Dispenses with External Synchronization A more complex dispensing example, this Program contains different pumping requirements, including dispenses with multiple pumping rates. The first set of 3 dispenses drops down to a lower pumping rate during the dispense. When each dispense is completed, the buzzer beeps to alert the operator, then the pump waits for a start trigger before starting the next dispense.
NEXT>>>ADVANCE www.nextadvance.com Phase 13 Function RATE Volume 17.25 ml Phase 14 Function BEEP Phase 15 Function PS:00 Phase 16 Function LP:EN Rate 900.0 ml/hr SP1600/1800 Programmable Syringe Pump Direction Withdraw 8.4.5 Example 5: Control from a High-Low Pressure Sensor This example demonstrates a Pumping Program whose control depends on an external sensor.
NEXT>>>ADVANCE Phase 7 Function EV:01 Phase 8 Function LP:ST Phase 9 Function INCR Phase 10 Function LP:14 Phase 11 Function RATE www.nextadvance.com Rate 1.0 Volume 0.25 ml Direction Infuse Rate 25.0 ml/hr Volume 0.0 ml (off) Direction Infuse SP1600/1800 Programmable Syringe Pump 8.4.
NEXT>>>ADVANCE Phase 6 Function LP:ST Phase 7 Function PS:60 Phase 8 Function LP:60 Phase 9 Function LP:05 Phase 10 Function LP:12 Phase 11 Function JP:01 www.nextadvance.com SP1600/1800 Programmable Syringe Pump 8.4.7 Example 7: Sub-Programs This example shows some of the flexiblities provided by the Program Selection functions.
NEXT>>>ADVANCE Phase 10 Function PR:03 Phase 11 Function RATE Phase 12 Function LP:05 Phase 13 Function JP:01 Rate 750.0 ml/hr www.nextadvance.com Volume 10 ml SP1600/1800 Programmable Syringe Pump Direction Infuse 8.4.8 Example 8: Dispensing with Complex Synchronization This example demonstrates a complex interaction with external equipment, such as synchronizing with another syringe pump.
NEXT>>>ADVANCE www.nextadvance.com Phase 4 Function OUT.0 Phase 5 Function ET:07 Phase 6 Function RATE Rate 800.0 ml/hr Volume 0.0 ml (OFF) Direction Infuse Phase 7 Function RATE Rate 1000.0 ml/hr Volume 0.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 9. RS-232 Communications The SP1600/SP1800 Syringe Pump can communicate with any computer or device with an RS-232 communications port. 9.1 Connection and Networking On the rear of the pump are 2 square RJ-11 (“phone jack” style) sockets. Connect the RS-232 cable into the socket labeled “To Computer”. Connect the other end to the serial port on the computer, or other control device.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 2 packet protocols are supported, Basic and Safe. The enabled communications protocol is stored in nonvolatile memory, and therefore will be in affect at power up. Safe Mode provides a safer communications protocol than Basic Mode. Safe Mode detects corrupted data and loss of communication, as well as automatically transmitting status packets when an alarm occurs.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 9.2.2 RS-232 Protocol: Basic Mode Command syntax (to pump): => Response syntax (from pump): => In the “Basic” communications mode, a master-slave protocol is used, whereby the pump will only transmit in response to a received command.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 9.2.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Send the following command, followed by a carriage return , (spaces are optional): 0 rat 100 * 1 rat 250 * 2 rat 375 * 9.3 Command Errors and Alarms If a command received by the pump is not recognized or the data is invalid, an error message will be in the field of the response packet following the field.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Set: Currently selected Phase is set to . Previous Phase is stored in non-volatile memory and the requested Phase is recalled from the non-volatile memory. Set is only valid if the Pumping Program is not operating. Query response: Currently selected Phase. PUMPING PROGRAM FUNCTION FUN [ ] Set/query the Pumping Program Phase’s function.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump While pumping, the pumping rate can only be set if the current Phase function is ‘RATE’ and the next Program Phase’s function to be executed is not ‘INCR’ or ‘DECR’. Also, while pumping, can not be set. The new pumping rate will only be stored in non-volatile memory if the Pumping Program is not operating. When the pumping rate is queried while pumping, the response will be the current pumping rate and units.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Queries volume dispense only. Set not applicable. Response: I W Where: “I “ refers to the infusion volume dispensed, and “W ” refers to the withdrawn volume. CLEAR VOLUME DISPENSED CLD { INF | WDR } Sets the Infused or withdrawn volume dispensed to 0. Command is only valid while the Pumping Program is not operating. Query is not applicable.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump ALARM SETUP AL [ ] Set/query alarm setup mode. Set alarm enables or disables alarm buzzer mode. POWER FAIL SETUP PF [ ] Set/query Power Failure mode. Set Power Failure enables or disables Power Failure mode. TTL I/O OPERATIONAL TRIGGER SETUP TRG [ ] Set/Query TTL I/O Operational Trigger input configuration. TTL I/O Operational Trigger is set to .
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Sets TTL level on user definable output pin on the ‘TTL I/O’ connector. Indicates pin number on ‘TTL I/O’ connector Valid value: 5 (Program Output pin) Query is not applicable. TTL INPUT QUERY IN Queries TTL level of pin on ‘TTL I/O’ connector. Set is not applicable. Indicates pin number on ‘TTL I/O’ connector Valid values: 2, 3, 4, and 6.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump From the terminal emulator, you can interactively control the pump by typing in commands on your computer and seeing the pump’s responses on your screen. This will give you a feel for how the commands work in addition to allowing you to quickly develop the control sequence that will eventually be coded into the software being developed.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 10. Logic Interface: TTL Input and Output NEW ERA PUMP SYSTEMS ™ WWW.SYRINGEPUMP.COM (631) 249-1392 Farmingdale, NY info@syringepump.com Figure 2: Rear of Pump On the rear of the pump is a DB-9 connector, below the ‘TTL-I/O’ label, which is used for TTL I/O. The logic signals on this connector permit bi-directional control with external equipment.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Pin # Definition Type Function 1 Vcc (5V) Reference Logic high reference. Power on indicator.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Pump Motor Operating (Pin 7): This output provides an external signal indicating when the pump n setup command, or the "ROM" remote motor is operating. This pin is configured with the command. When set to 0, the output is only at logic high when the motor is operating (pumping). When set to 1, the output is logic high when the motor is operating or when the Pumping program is executing a pause timer.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 11. Appendix 11.1 Syringe Diameters and Rate Limits Manufacturer B-D Maximum Minimum Inside Syringe Diameter Rate Rate (cc) (mm) (mL/hr) (µl/hr) 1 4.699 34.67 0.454 3 8.585 115.7 1.515 5 11.99 225.7 2.954 10 14.43 327 4.279 20 19.05 569.9 7.457 30 21.59 732 9.578 60 26.59 1110 14.53 Monoject 1 3 6 12 20 35 60 5.74 8.941 12.7 15.72 20.12 23.52 26.64 51.74 125.5 253.3 388 635.7 868.7 1114 0.677 1.643 3.314 5.078 8.318 11.37 14.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 11.2 RS-232 Command Summary => DIA [ < float > ] PHN [ < phase data > ] FUN [ < phase function > ] < phase function > => RAT INC DEC STP JMP PRI PRL LOP LPS LPE PAS PAS [n.
www.nextadvance.com NEXT>>>ADVANCE SP1600/1800 Programmable Syringe Pump 11.3 RS-232 Pump Network Connector Wiring RS-232 To Network To Computer RCV from network TXD to computer TXD to network RCV from computer PC Com Port Connectors 25 Pin 9 Pin 3 - Receive 2 - Receive Connect to pump TXD 2 - Transmit 3 - Transmit Connect to pump RCV 9 - Ground 5 - Ground Connect to pump GND 11.4 Accessories 11.4.1 ANA-BOX Part #: ADPT-ANABOX, Analog sensor interface.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 11.4.4 Automation Cable: Reciprocating/Dual Pumps Control Cable Part #: CBL-DUAL Using two NE-1000 syringe pumps, this cable either creates an automated, continuous operation pumping system, whereby one pump is refilling while the other is dispensing, or creates a dual pumping system, with both pumps operating in the same direction. This cable is attached to two NE-1000 syringe pumps via their RS-232 connectors.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump Pusher block makes a snap or click sound when the pump is started: This is a normal condition. When the pusher block is manually moved, the drive-nut may not have been fully engaged on the drive screw. The sound heard is the drive-nut engaging on the drive screw. Pump doesn’t stop after dispensing a set volume: The pump was previously setup with a multiple Phase Pumping Program.
NEXT>>>ADVANCE www.nextadvance.com SP1600/1800 Programmable Syringe Pump 11.6 Specifications 11.6.
