SyringePump.com Models: NE-1200 / NE-1600 / NE-1800 Multi-Phaser™ NE-1000 Series of Programmable Syringe Pumps NE-1600 NE-1800 NE-1200 6 Syringes up to 140 mL 8 Syringes up to 10 mL 12 Syringes up to 3 mL Infusion Rate 60 50 40 30 20 10 0 0 10 20 30 40 50 60 70 80 90 Time “WHAT’S YOUR APPLICATION?”™ WARNING NOT FOR CLINICAL USE ON HUMANS Publication #1200-02 Revision 18 V3.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Quick Start Instructions Assumes that the pump was not previous programmed with a multiple Phase Pumping Program. • • • Plug in the pump. Press the power switch to turn on power. Press any key to stop the display from blinking. Setup Pumping Parameters To Change Numbers: • Use the up-arrow keys to increment individual digits.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Table of Contents 1. General Information ....................................................................................................................... 1 ! Warnings 1.2 Disclaimer ............................................................................................................................................... 1 1.3 Warranty .........................................................................
New Era Pump Systems Inc. 6.1.1 6.1.2 WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Default Volume Units .................................................................................................................................... 12 Changing Volume Units ................................................................................................................................. 12 6.2 Start/Stop Triggers ............................................................................
New Era Pump Systems Inc. 8.4.1 8.4.2 8.4.3 8.4.4 8.4.5 8.4.6 8.4.7 8.4.8 8.4.9 9. Example 1: Example 2: Example 3: Example 4: Example 5: Example 6: Example 7: Example 8: Example 9: WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 2 Step Rate ................................................................................................................................. 23 Repeated Dispenses with Suck Back .........................................................................................
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 1. General Information Thank you for purchasing the NE-1200/NE-1600/NE-1800 Multi-Phaser™ Programmable Multi-Syringe Pump. With the NE-1200/NE-1600/NE-1800 syringe pumps you will be able to perform simple infusions or implement a complex automated dispensing system. Please familiarize yourself with the syringe pump’s operation by reading this user's manual.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 1.3 Warranty New Era Pump Systems Inc. warranties this product and accessories for a period of two years, parts and labor, from the date of purchase. The repaired unit will be covered for the period of the remainder of the original warranty or 90 days, whichever is greater. Return shipping charges are not included. A return authorization number must be obtained from New Era Pump Systems Inc.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 2.1 Glossary of Terminology and Concepts When a device has as many features as the models NE-1200/NE-1600/NE-1800, understanding its operation could be a daunting task at first. By understanding the key concepts and terminology used in this manual, the operation of the syringe pump will become quite intuitive. Every effort has been made to design the syringe pumps with a consistent and intuitive user interface.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Parts of a Syringe Plunger Flange Plunger Barrel Flange Barrel Terminology Momentary Press: A quick press, less than 1 second, and then release of a key on the keypad. Display Blink: A momentary blanking of the LCD display. This indicates that the new data entered by the user is valid and has been stored. Program Entry Mode: The mode where the Program Phase and Program function are selected and modified.
New Era Pump Systems Inc. Start Trigger: WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ The Pumping Program may be started, or stopped, from multiple sources. These are the keypad’s ‘Start’/’Stop’ key, the TTL I/O ‘Operational Trigger’ input, or from a command received through the RS-232 connection. 3. Setup ♦ Place the pump on a stable surface. ♦ Plug the round connector end of the supplied power supply adapter into the power plug located on the lower right of the pump's rear.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 5. User Interface RS-232 Indicator Volume Dispensed Units Pumping Direction Motor Indicators Indicator Operating Indicator Volume Dispensed min Withdraw hr Syringe ID mm mL µL Rate Volume Pumping Diameter Start Setup Stop Pumping Program Phase # Function Decimal Point: Press 2 keys Program Entry Keys Pumping Direction Key Figure 1: Front Panel 5.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ ‘Withdraw’ indicates that the pumping direction is set for withdrawing. If not lit, then the pumping direction is set for infusing. When blinking, “Sticky Direction” is set. Also, the ‘Withdraw’ LED indicates that the “Volume Dispensed” refers to the volume withdrawn. If not lit, the “Volume Dispensed” refers to the volume infused.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 5.6 ‘Rate’ and ‘Program Phase #’ Key When the Pumping Program is stopped, except in “Program Entry Mode”, the ‘Rate’ key allows the pumping rate to be viewed or changed. If the currently selected function allows selection of rate units, momentarily pressing this key will switch between the ‘Rate’ display and the select rate units mode. To change the pumping rate displayed, use the up arrow keys (see sec. 5.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ for one second will reset the infusion and withdrawal dispensed volumes to 0. 5.7.3 Program Entry Mode “Program Entry Mode” is entered by pressing and holding the ‘Volume’ key. Release the key when the display shows the currently selected Program Phase’s function. In “Program Entry Mode”, when the Program Function is not displayed, momentarily pressing this key will display the current Program Function.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ When the Program Phase number is displayed and the current Phase’s function is a rate function, a momentary press of the ‘Program Phase #’ key exits ‘Program Entry Mode, and displays the pumping rate. To change the current Program Phase number, press the arrow keys below the Phase number’s digits. The maximum Phase number is 41.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 5.13.3 Default Program Pre-Load Pressing the 'Volume'/'Program Function' key while turning on power to the pump will display the Default Program Menu and the display will show: . Currently, the only default program is the Reciprocating Pump program. When selected, the following program will be pre-set, plus the RS-232 communications mode will be set to Reciprocating Mode. The default program can be modified as needed.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Indicates that the Pumping Program has paused and is waiting for the user to press ‘Start’, or for an external operational trigger, to continue. Indicates that the pump is busy completing a long operation. Indicates that the “Volume to be Dispensed” is 0.00, and is turned off. This is the continuous pumping mode. Indicates that the pump is purging. Displayed while holding down the 'Start/Stop' key.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ wait 2 seconds to enter the new Volume Units. The display will blink when entered. The selected Volume Units will remain in affect and override the default Volume Units. Changing the diameter will no longer change the Volume Units. Performming a system reset will cancel the override and allow the Volume Units to change to the default Volume Units when setting the syringe diameter. 6.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 6.7 Resuming When Paused If the Pumping Program is stopped before the completion of the Pumping Program, the ‘Pumping’ LED will blink, indicating that the Pumping Program is paused. While the ‘Pumping’ LED is blinking, starting the pump again will resume the Pumping Program where it was stopped.
New Era Pump Systems Inc. nnnn WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ RS-232 pump network baud rate, where ‘nnnn’ indicates the baud rate. Otherwise, the current communications mode will be displayed: , , or Communications Mode. Reciprocating, Dual Pump, or Alternating 7.1 Power Failure Mode n Setting: ‘0’ = Disabled, ‘1’ = Enabled.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ When enabled, a beep will sound as follows: Condition Buzzer Action Pumping Program ended Continuous beeping Pumping Program paused for start trigger Continuous beeping A keypad button is pressed Single beep 7.9 RS-232 Pump Network Configuration nn The pump can be configured to communicate either with a computer or another pump.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ immediately start the next consecutive Phase. This linear sequence of Phases can be altered by certain functions that direct the Pumping Program to continue operation with a different Phase number. Some functions can change the order of operation conditionally based on external events. 8.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.2 Pumping Program Edit Functions When developing or updating a large Pumping Program, occasionally one or more Program Phases needs to be added or removed from the Pumping Program. Having to re-enter the entire Program could certainly be a tedious task. Two Program entry functions are available to simplify the Program development process. These are the ‘Insert’ and ‘Delete’ functions.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ automatcally refill the syringe. The Volume Dispensed is cleared when the Fill Function begins. The pumping rate can be set, as with the Rate Function. Fill at the current dispense/withdraw rate: If the Fill function’s pumpng rate is set to 0.0, the previous function’s pumping rate will be used for the Fill rate. 8.3.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM again. If the selected label is not found, the 'out of range' error message any key returns the display to the Program Selection Input display. Model NE-1600/NE-1800 Multi-Phaser™ is displayed. Pressing If more than one Phase is defined with the same label, then execution continues with the first matching label encountered.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ or cleared, as required. Now enter the required pause time from 0.1 to 9.9 seconds. While executing a pause time set in tenths of seconds, the display will only show '01' seconds during the pause. For pauses longer than the ‘99’ second maximum pause for this function, put the pause function within a Program loop.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.3.18 ‘tr:aa’: Override Operational Trigger Configuration aa Sets the Operational Trigger (pin 2) to mode ‘aa’, overriding the default setup Operational Trigger Configuration. See Sec.7.4,”TTL I/O Operational Trigger Default Configuration”, for the settings for parameter ‘aa’. The default setting for the Operational Trigger is always used to start the Pumping Program. 8.3.18.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ ml/hr Rate 8.4.2 Example 2: Repeated Dispenses with Suck Back 750 0 0 :30 5:00 Time Dispense 2.0 mL with a 5 minute pause between dispenses. In addition, after each dispense, a volume of 0.25 mL is sucked back to prevent dripping. Also, 30 seconds before the end of the pause interval, a beep is sounded to alert the operator to prepare for the next dispense. Starting with the second dispense, 0.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.4.3 Example 3: Ramping the Flow Rate ml/hr Rate Phases 2-4 Phases 5-8 250 Phases 9-11 200 150 0 Time Note: Graph is representative only. Pumping rate increments and decrements in steps. Continuously ramp up and down the pumping rate. Starting at 200 mL/hr, the pumping rate will increment to 250 mL/hr in 1.0 mL/hr steps after every 0.1 mL has been dispensed. Then the pumping rate will decrement to 150 mL/hr in 1.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Withdraw (ml/hr) Infuse 8.4.4 Example 4: Complex Dispenses with External Synchronization 750 Start over 0 0 Start Trigger :60 :60 :60 Syringe Refill Start Trigger Start Trigger A more complex dispensing example, this Program contains different pumping requirements, including dispenses with multiple pumping rates.
New Era Pump Systems Inc. Phase 15 Function PS:00 Phase 16 Function LP:EN WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.4.5 Example 5: Control from a High-Low Pressure Sensor ml/hr 25 Pumping Rate 10 Program Output Pin Pressure high sensor Pressure low sensor Event Input Pin Pressure trigger points This example demonstrates a Pumping Program whose control depends on an external sensor.
New Era Pump Systems Inc. Phase 9 Function INCR Phase 10 Function LP:14 Phase 11 Function RATE WWW.SYRINGEPUMP.COM Rate 1.0 Volume 0.25 mL Direction Infuse Rate 25.0 mL/hr Volume 0.0 mL (off) Direction Infuse Model NE-1600/NE-1800 Multi-Phaser™ 8.4.
New Era Pump Systems Inc. Phase 9 Function LP:05 Phase 10 Function LP:12 Phase 11 Function JP:01 WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.4.7 Example 7: Sub-Programs This example shows some of the flexibilities provided by the Program Selection functions. The Pumping Program starts by refilling the syringe with 50 mL at a fast pumping rate (Phase 1), then the Pumping Program pauses for user sub-program selection (Phase 3).
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.4.8 Example 8: Dispensing with Complex Synchronization Restart on Event Trigger or 10 seconds Withdraw Infuse Infuse until Event Trigger Repeat if Program Input low :01 TTL High TTL Low TTL Program Ouput :10 :10 Event Trigger Event Trigger This example demonstrates a complex interaction with external equipment, such as synchronizing with another syringe pump.
New Era Pump Systems Inc. Phase 10 Function PS:10 Phase 11 Function ET:01 Phase 12 Function PS:10 Phase 13 Function JP:01 WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 8.4.9 Example 9: Automatic Refill While a foot switch is held, dispense continuously, starting with a 1.5 mL bolus. When the foot switch is released, the syringe will refill to the volume that was dispensed. In the pump’s general setup, set the TTL Trigger to “Foot Switch Hold” mode (TR:FH).
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ disrupted, causing communications errors. In these situations, a lower baud rate may improve the reliability of the communications. 9.2 RS-232 Protocol When the pump is used in a multi-pump network configuration, precede each command with a pump address. Pumps will ignore all commands that do not have their defined network address. If the network address is not specified in the command, the address will default to 0.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ => { 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 } Digits => “one byte of any data” () One byte of data expressed as (0xhh), where ‘hh’ is the data in hexadecimal. => Is defined by. Syntax expands to next level of expansion. <> Non-terminal syntax expansion [] Optional syntax {} Required syntax | Or. Choose one of the syntax options. λ None. Syntax expands to nothing (lambda production).
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Alarm feature, therefore, alerts the host computer that a pump reset has occurred. Also, when the user changes the baud rate, the communications time out timer is disabled until the next valid communications packet. 9.2.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ => ? => λ NA OOR COM IGN Command is not recognized (‘?’ only) Command is not currently applicable Command data is out of range Invalid communications packet received Command ignored due to a simultaneous new Phase start When an alarm occurs, the alarm must be acknowledged before any data is changed or the pump is started.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ not operating For a more detailed description of Program commands, see sec. 8.3, Program Function Descriptions. => Rate Data Functions When a Phase’s function is set to a “Rate Data Function”, use the ‘RAT’, ‘VOL’, and ‘DIR’ commands to setup the pumping parameters. RAT FIL INC DEC STP PAS PAS PRI PRL LPS LPE LOP JMP IF EVN EVS EVR CLD TRG BEP OUT Pumping rate. ‘RATE’ Fill syringe to dispensed volume.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ RAT I [ ] Changes the pumping rate only if the pump is infusing. If the pumping direction is set to withdraw, the rate change will be ignored. VOLUME TO BE DISPENSED AND SET VOLUME UNITS VOL [ | ] Set/query volume to be dispensed: Applicable only with “Rate Data Functions”. Can only be set when the Pumping Program is not operating.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ PURGE PUMP PUR Starts purge. Pump infuses or withdraws at the top speed, depending on the pumping direction. STP command or ‘Start/Stop’ key will stop the pump. STOP PUMPING PROGRAM STP If the Pumping Program is operating, the pump will be stopped and the Pumping Program will be paused. If the Pumping Program is paused, the stop command will cancel the pause and reset the Pumping Program.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM OF Model NE-1600/NE-1800 Multi-Phaser™ = Trigger off (disabled) TTL I/O DIRECTIONAL CONTROL INPUT SETUP DIN [ 0 | 1 ] Set/query directional control input setup Settings => 0 = Falling edge: Infuse, Rising edge Withdraw Same as "dr:rE" setting from the keypad. Use this setting with the CBL-TTL-1, reciprocating pump cable, to create a 2 pump continuous infusion system 1 = Falling edge: Withdraw, Rising edge Infuse Same as "dr:dU" setting from the keypad.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Query response: { 0 | 1 } 0 = Buzzer off 1 = Buzzer is on continuously or beeping. 9.4.5 System Commands SET PUMP NETWORK ADDRESS AND BAUD RATE * ADR [
[ B { 19200 | 9600 | 2400 | 1200 | 300 } ] ] [DUAL | RECP | ALTR] Set/query pump network address => [] Valid range: 0 to 99 B { 19200 | 9600 | 2400 | 1200 | 300 } will change the baud rate as indicated.New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 9.5 Getting Started With RS-232 Before beginning to develop pump control software for a computer, first setup and experiment with the pump’s communication. After attaching the pump to the computer, run a terminal emulation Program on the computer. A generic terminal emulator, supplied as standard software with many computers, can be used to communicate with the pump in the Basic communications mode.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 10. Logic Interface: TTL Input and Output NEW ERA PUMP SYSTEMS ™ WWW.SYRINGEPUMP.COM (631) 249-1392 Farmingdale, NY info@syringepump.com Pin 1 Pin 9 Figure 2: Rear of Pump On the rear of the pump is a DB-9 connector, below the ‘TTL-I/O’ label, which is used for TTL I/O. The logic signals on this connector permit bi-directional control with external equipment.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Pin # Definition Type Function 1 Vcc (5V) Reference Logic high reference. Power on indicator.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Level Control: Falling edge stops/pauses the Pumping Program, Rising edge starts the Pumping Program. This configuration can be used with a contact closure timer or in an automation setup, allowing logic level control over the operation of the pump. Start Only: Falling edge starts the Pumping Program. This configuration only allows the starting of the Pumping Program.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ 10.3 TTL I/O Control from RS-232 The logic levels of pins 2, 3, 4, and 6 can be queried from an attached computer using the RS-232 ‘IN’ command. The output logic level of pin 5 can be set with the RS-232 ‘OUT’ command. 11. Appendix 11.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ *RESET Resets pump. Clears program memory and resets setup. -----------------------------------------------------------------------------------------------------------------------------Network Command Burst => * [Network Command Burst] - Communicate simultaneously with multiple pumps on a pump network. Any command preceded by the asterisk symbol ‘*’ bypasses the pump network address and Safe mode. 11.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ USB to RS-232 Converter Cable USB to RS-232 cable, software drivers on CD Part#: CBL-USB232 Attached to the RS-232 Network Primary Cable, allows communication through a PC’s USB port. 11.3.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM Model NE-1600/NE-1800 Multi-Phaser™ Using a lower baud rate may also improve the reliability of the RS-232 communications. Pusher block makes a snap or click sound when the pump is started: This is a normal condition. When the pusher block is manually moved, the drive-nut may not have been fully engaged on the drive screw. The sound heard is the drive-nut engaging on the drive screw.
New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM 11.7 Syringe Diameters and Rate Limits Syringe Syringe Inside Maximum Minimum Maximum Manufacturer (mL) Diameter Rate Rate Rate (all names ™) (mm) (mL/hr) (µL/hr) (mL/min) B-D HSW Norm-Ject Monoject Terumo Poulten & Graf (Glass) Steel Syringes SGE (gas tight) Hamilton Microliter Model NE-1600/NE-1800 Multi-Phaser™ 1 4.699 36.33 0.454 0.605 3 8.585 121.2 1.515 2.021 5 11.99 236.5 2.954 3.942 10 14.43 342.6 4.279 5.71 20 19.05 597.1 7.457 9.952 30 21.