SyringePump.com Model: NE-1000 Multi-Phaser™ NE-1000 Series of Programmable Syringe Pumps Firmware Version: V3.919 Infusion Rate 60 50 40 30 20 10 0 0 10 20 30 40 50 60 70 80 90 Time “WHAT’S YOUR APPLICATION?”™ WARNING NOT FOR CLINICAL USE ON HUMANS Publication #1200-01 Firmware Version: V3.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Quick Start Instructions Assumes that the pump was not previous programmed with a multiple Phase Pumping Program. • • • Plug in the pump. Press the power switch to turn on power. Press any key to stop the display from blinking. Setup Pumping Parameters To Change Numbers: • Use the up-arrow keys to increment individual digits.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Table of Contents 1. GENERAL INFORMATION .............................................................................................. 1 1.1 1.2 1.3 1.4 2. WARNINGS ! AND CAUTIONS ! .............................................................................. 1 DISCLAIMER .................................................................................................................... 1 WARRANTY .............................
New Era Pump Systems Inc. 7.5 7.6 7.7 7.8 8. www.SyringePump.com Model NE-1000 Multi-Phaser™ CHANGING THE PUMPING RATE AND DIRECTION WHILE PUMPING ........................ 13 VOLUME DISPENSED..................................................................................................... 13 RESUMING WHEN PAUSED ........................................................................................... 14 PUMP STALLED ...................................................................................
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 10.2 RS-232 PROTOCOL: .................................................................................................. 32 10.2.1 RS-232 GENERAL SYNTAX LEGEND ....................................................................... 32 10.2.2 RS-232 PROTOCOL: BASIC MODE .......................................................................... 33 10.2.3 RS-232 PROTOCOL: SAFE MODE .....................................................
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ 1. General Information Thank you for purchasing the NE-1000 Multi-Phaser™ Programmable Syringe Pump. With the NE-1000 syringe pump you will be able to perform simple infusions or implement a complex automated dispensing system. Please familiarize yourself with the NE-1000’s operation by reading this user's manual. For future reference, record the serial number, located on the rear of the pump, and the date of purchase.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ A return authorization number must be obtained from New Era Pump Systems Inc. before returning a unit for repair. Warranty covered repairs will not be performed without a return authorization number. At the option of New Era Pump Systems Inc., a defective unit will be either repaired or replaced.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ 2.1 Glossary of Terminology and Concepts When a device has as many features as the NE-1000, understanding its operation could be a daunting task at first. By understanding the key concepts and terminology used in this manual, the operation of the NE-1000 will become quite intuitive. Every effort has been made to design the NE-1000 with a consistent and intuitive user interface.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Terminology Momentary Press: A quick press, less then 1 second, then release of a key on the keypad. Display Blink: A momentary blanking of the LCD display. This indicates that the new data entered by the user is valid and has been stored. Program Entry Mode: The mode where the Program Phase and Program function are selected and modified.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 3. Setup ♦ Place the pump on a stable surface. ♦ Plug the round connector end of the supplied power supply adapter into the power plug located on the lower right of the pump's rear. See section 11, Logic Interface: TTL Input and Output, for a diagram of the rear of the pump. Plug the other end of the power supply adapter into an appropriate electrical outlet.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ 6. User Interface RS-232 Indicator Volume Dispensed Units Pumping Direction Motor Indicators Indicator Operating Indicator Volume Dispensed min Withdraw hr Syringe ID mm mL µL Rate Volume Pumping Diameter Start Setup Stop Pumping Program Phase # Function Decimal Point: Press 2 keys Program Entry Keys Pumping Direction Key Figure 1: Front Panel 6.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ “Volume Dispensed” refers to the volume withdrawn. If not lit, the “Volume Dispensed” refers to the volume infused.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 6.6 ‘Rate’ and ‘Program Phase #’ Key When the Pumping Program is stopped, except in “Program Entry Mode”, the ‘Rate’ key allows the pumping rate to be viewed or changed. If the currently selected function allows selection of rate units, momentarily pressing this key will switch between the ‘Rate’ display and the select rate units mode. To change the pumping rate displayed, use the up arrow keys (see sec.6.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 6.7.2 Clearing “Volume Dispensed” With the Pumping Program stopped, display the “Volume Dispensed”. Pressing and holding any up arrow key for one second will reset the infusion and withdrawal dispensed volumes to 0. 6.7.3 Program Entry Mode “Program Entry Mode” is entered by pressing and holding the ‘Volume’ key. Release the key when the display shows the currently selected Program Phase’s function.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 6.10 ‘Program Phase #’ (Number) Key When in the “Program Entry Mode”, momentary presses of the ’Program Phase #’ and the ‘Program Function’ keys switch between the Program Phase number and the Program Function displays. The Program Phase number will be displayed as nn , where ‘nn’ is the current Program Phase number.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ 6.13.2 Reset Pumping Program To clear out the current Program Function setups, press the right-most up-arrow key ( ) while turning on power to the pump. The display will show . Pressing any key will clear the display. With a pump with as many complex features as the NE-1000, it is easy for a novice user experimenting with the pump's setup to get the pump into a 'weird' state.
New Era Pump Systems Inc. n www.SyringePump.com Model NE-1000 Multi-Phaser™ An error was detected during power up, where ‘n’ indicates the error. If n=1, then the values stored in the pump’s non-volatile memory were invalid and were reset. If n=2, then the non-volatile memory may need to be replaced. Pump settings are locked out from the keypad. The lockout key is needed to change settings. Lockout can also be reset with the reset function. 6.15 Status Messages Indicates pumping rate units change mode.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ To change the Volume Units, display the “Volume Dispensed” by pressing the “Volume” key once or twice. The current Volume Units and the “Dispensed” LED will be lit. Set the Volume Dispensed to 0.000 if it is not zero: Press and hold any up arrow key until the Volume Dispensed is set to 0.000. Now, pressing any up arrow key will change the display to blink.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ The “Volume Dispensed” accumulations for infusion and withdrawal are reset to 0 when: A) With the pump stopped, pressing and holding any up arrow key while displaying the “Volume Dispensed”. B) A sub-program is selected when the Pumping Program executes a Program Selection function. C) The syringe diameter is changed. D) From the RS-232 clear “Volume Dispensed” command (CLD) or Clear Dispense function.
New Era Pump Systems Inc. nn nnnn www.SyringePump.com Model NE-1000 Multi-Phaser™ RS-232 pump network address, where ‘nn’ is the network address. RS-232 pump network baud rate, where ‘nnnn’ indicates the baud rate. Otherwise, the current communications mode will be displayed: , , or Communications Mode. Reciprocating, Dual Pump, or Alternating 8.1 Power Failure Mode n Setting: ‘0’ = Disabled, ‘1’ = Enabled.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ P2 7 Stop Only Reversed Rising edge stops the Pumping Program rL 8 Start on Low Level Start Pumping Program on a low level rH 9 Start on High Level Start Pumping Program on a high level SL 10 Stop on Low Level Stop Pumping Program on a low level SH 11 Stop on High Level Stop Pumping Program on a high level oF 12 Trigger off Disable trigger Et 13 Trigger Event Pumping Program Function Only:.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ The "Lockout Disable Key" connects the "Program Input", TTL connector pin 6, to Ground, pin 9. The "Lockout Disable Key" is available as an accessory item. Lockout can also be disabled by performing a system reset, see sec. 6.13.2, "Reset Pumping Program." 8.8 Keypad and Notification Beep Enable n Setting: ‘0’ = Disabled, ‘1’ = Enabled.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Program can interact with external devices through the TTL I/O connector, make decisions, or stop pumping for a period of time. Programs are broken into individual operations called Phases. Each Phase consists of a function that can be a control function or pumping function. A pumping function, such as ‘RATE’, consists of a pumping rate, optional “Volume to be Dispensed”, and the pumping direction.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 9.1.1 Pumping Program Phase Number To set the current Program Phase number, enter “Program Entry Mode” and display the current Program Phase number. Using the right-most 2 arrow keys, change the selected Program Phase number. The displayed Program Phase number now becomes the currently selected Program Phase number. All function and pumping rate data will now refer to the currently selected Program Phase number.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 9.3 Program Function Descriptions Each program function must be in a separate Program Phase 9.3.1 ‘rAtE’: Rate Function Defines a pumping function with a fixed pumping rate. This function defines a pumping setup consisting of the pumping rate, optional “Volume to be Dispensed”, and pumping direction. Use the ‘Rate’, ‘Volume’, and ‘Pumping Direction’ keys to set or review the pumping setup.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ of production dispenses to be programmed into the pump. The user then would only be able to select from one of these production dispenses and not make any changes.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ When a ‘loop end’ function is executed, Program operation continues with the ‘loop start’ function paired with the loop end function. There are 2 ‘loop end’ functions: Loop continuous (‘LP:EN’) and Loop for a preset number of iterations (‘LP:nn’), indicated by ‘nn’. Each time a paired ‘loop end’ function is executed, an iteration of the loop is complete.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ After being triggered, the event trigger is reset. If an event trigger function is executed (either 'Et' or ES' function) while another event trap is still set, the new event trigger will replace the previous event trap. Only one event can be defined at any time. 9.3.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ 9.4 Pumping Program Examples ml/h r Rate 9.4.1 Example 1: 2 Step Rate 500 2.5 0 30 ml Dispensed 05 Infuse 5.0 mL at 500 mL/hr, and then infuse 25.0 mL at 2.5 mL/hr. Then stop the pump. Phase 1 Function RATE Rate 500 mL/hr Volume 5.0 mL Direction Infuse Phase 2 Function RATE Rate 2.5 mL/hr Volume 25.0 mL Direction Infuse Phase 3 Function STOP ml/hr Rate 9.4.
www.SyringePump.com New Era Pump Systems Inc. Phase 7 Function BEEP Phase 8 Function PS:30 Phase 9 Function RATE Rate 750 mL/hr Volume 2.25 mL Direction Infuse Phase 10 Function RATE Rate 750 mL/hr Volume 0.25 mL Direction Withdraw Phase 11 Function LP:EN Model NE-1000 Multi-Phaser™ 9.4.3 Example 3: Ramping the Flow Rate ml/hr Rate Phases 2-4 Phases 5-8 250 Phases 9-11 200 150 0 Time Note: Graph is representative only. Pumping rate increments and decrements in steps.
www.SyringePump.com New Era Pump Systems Inc. Phase 11 Function LP:50 Phase 12 Function JP:02 Model NE-1000 Multi-Phaser™ Withdraw (ml/hr) Infuse 9.4.4 Example 4: Complex Dispenses with External Synchronization 750 Start over 0 0 Start Trigger :60 :60 :60 Syringe Refill Start Trigger Start Trigger A more complex dispensing example, this Program contains different pumping requirements, including dispenses with multiple pumping rates.
New Era Pump Systems Inc. Phase 12 Function LP:03 Phase 13 Function RATE Phase 14 Function BEEP Phase 15 Function PS:00 Phase 16 Function LP:EN www.SyringePump.com Rate 900.0 mL/hr Volume 17.25 mL Model NE-1000 Multi-Phaser™ Direction Withdraw 9.4.
www.SyringePump.com New Era Pump Systems Inc. Phase 6 Function RATE Phase 7 Function EV:01 Phase 8 Function LP:ST Phase 9 Function INCR Phase 10 Function LP:14 Phase 11 Function RATE Rate 10.0 mL/hr Volume 0.005 Direction Infuse Rate 1.0 Volume 0.25 mL Direction Infuse Rate 25.0 mL/hr Volume 0.0 mL (off) Direction Infuse Model NE-1000 Multi-Phaser™ 9.4.
New Era Pump Systems Inc. Phase 6 Function LP:ST Phase 7 Function PS:60 Phase 8 Function LP:60 Phase 9 Function LP:05 Phase 10 Function LP:12 Phase 11 Function JP:01 www.SyringePump.com Model NE-1000 Multi-Phaser™ 9.4.7 Example 7: Sub-Programs This example shows some of the flexibilities provided by the Program Selection functions.
www.SyringePump.com New Era Pump Systems Inc. Phase 11 Function RATE Phase 12 Function LP:05 Phase 13 Function JP:01 Rate 750.0 mL/hr Volume 10 mL Model NE-1000 Multi-Phaser™ Direction Infuse 9.4.
New Era Pump Systems Inc. www.SyringePump.com Phase 6 Function RATE Rate 800.0 mL/hr Volume 0.0 mL (OFF) Direction Infuse Phase 7 Function RATE Rate 1000.0 mL/hr Volume 0.25 mL Direction Withdraw Phase 8 Function PS:01 Phase 9 Function IF:07 Phase 10 Function PS:10 Phase 11 Function ET:01 Phase 12 Function PS:10 Phase 13 Function JP:01 Model NE-1000 Multi-Phaser™ 9.4.9 Example 9: Automatic Refill While a foot switch is held, dispense continuously, starting with a 1.5 mL bolus.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ on the next pump in the network. Up to 100 pumps can be networked together with a computer. See section 11, Logic Interface: TTL Input and Output, for a diagram of the rear of the pump. When communicating with a pump in a multi-pump network, each preceding pump in the network must be powered on. Each pump in the network needs a unique network address to identify the pump to the computer. Network addresses are from 00 to 99.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ => [ ] Floating point number. Maximum of 4 digits plus 1 decimal point. Maximum of 3 digits to the right of the decimal point. => UL ML µL (microliters) mL (milliliters) => 1 0 TTL high level TTL low level => 1 0 On, enabled Off, disabled => [] Program Phase number.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Safe mode uses a modified master-slave protocol, whereby the pump transmits in response to a received command. But, the pump also automatically transmits a status packet when an alarm condition occurs. Corrupted communications is detected using the 16 bit CCITT CRC algorithm computed over . Packets transmitted and received include the CRC within the packets.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 10.2.5 Network Command Burst The Network Command Burst feature is only applicable when communicating to a network of pumps. This special feature allows commands to be sent to a network of pumps simultaneously. For example, changing the pumping rates simultaneously on a network of pumps.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ All commands are upper case. => DIAMETER DIA [ ] Set/query inside diameter of syringe. Set is only valid when the Pumping Program is not operating. Setting the syringe diameter also sets the units for “Volume to be Dispensed” and “Volume Dispensed”. 10.4.1 Program Function Commands The following commands are relevant to the currently select Program Phase.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ PUMPING RATE RAT [ C | I ] [ [ ] ] Set/query pumping rate. => UM MM UH MH = µL/min = mL/min = µL/hr = mL/hr Applicable only with “Rate Data Functions”. When setting the pumping rate, if the current Phase’s function is not ‘RATE’, then is not applicable.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Query response: { INF | WDR | STK} While pumping, when set to “Sticky Direction”, query will respond with the current pumping direction ( INF or WDR). 10.4.2 Pump Operational Commands START PUMPING PROGRAM RUN [ ] [E [ ] ] Starts the Pumping Program operation. If the Pumping Program was paused, then the Pumping Program resumes at the point where it was stopped.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ ALARM SETUP AL [ ] Set/query alarm setup mode. Set alarm enables or disables alarm buzzer mode. POWER FAIL SETUP PF [ ] Set/query Power Failure mode. Set Power Failure enables or disables Power Failure mode. TTL I/O OPERATIONAL TRIGGER DEFAULT SETUP TRG [ ] Set/Query TTL I/O Operational Trigger (Pin 2) default input configuration. TTL I/O Operational Trigger is set to .
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ ‘Volume’ and Pumping Direction can be changed. Cannot be enabled when the Pumping Program is currently programmed with a multiple Phase Program. SET KEYPAD AND NOTIFICATION BEEP BP [ ] Set/query keypad and notification beep mode. Set beep enables or disables beep mode. 10.4.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Note: Once a special communications mode is set, the pump will only respond to commands that are preceded by the ‘*’ character. To exit special communication mode, reset the address: * ADR 0 Example: *ADR Query current address setting *ADR 3 Set pump network address to 3. The pump will now only respond to commands with address 3 *ADR 5 B 1200 Set the pump network address to 5 and the baud rate to 1200.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 11. Logic Interface: TTL Input and Output New Era Pump Systems Inc. WWW.SYRINGEPUMP.COM (631) 249-1392 Farmingdale, NY info@syringepump.com Pin 1 12 Pin 9 Figure 2: Rear of Pump On the rear of the pump is a DB-9 connector, below the ‘TTL-I/O’ label, which is used for TTL I/O. The logic signals on this connector permit bi-directional control with external equipment.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ Pin # 1 2 Definition Vcc (5V) Operational Trigger Type Reference Input 3 Pumping Direction Input 4 5 6 Event Trigger Program Output Program Input Input Output Input 7 Pump Motor Operating Output [RUN.0] High: Pumping; Low: Not pumping [RUN.
New Era Pump Systems Inc. Stop Only: www.SyringePump.com Model NE-1000 Multi-Phaser™ Falling edge Stops the Pumping Program. This configuration only allows the stopping/pausing of the Pumping Program. This would be useful, for example, with an end of travel limit switch. Also, this switch can be used as a power on homing switch. Stop Only Reversed: Same as ‘Stop Only’, but operates on the Rising edge to stop the Pumping Program.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 12. Appendix 12.1 RS-232 Command Summary => DIA [ < float > ] Syringe inside diameter PHN [ < phase data > ] Program Phase number FUN [ < phase function > ] Program Phase function < phase function > => RAT Pumping rate. ‘RATE’ FIL Fill syringe to volume dispensed. ‘FILL’ INC Increment rate. ‘INCR’ DEC Decrement rate. ‘DECR’ STP Stop pump. ‘STOP’ JMP Jump to Program Phase.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 12.2 RS-232 Pump Network Connector Wiring RS-232 To Network To Computer RCV from network TXD to computer TXD to network RCV from computer PC Com Port Connectors 25 Pin 9 Pin 3 - Receive 2 - Receive Connect to pump TXD 2 - Transmit 3 - Transmit Connect to pump RCV 9 - Ground 5 - Ground Connect to pump GND 12.3 Accessories 12.3.1 ANA-BOX™ Part #: ADPT-ANABOX, Analog voltage control interface.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 12.3.4 Automation Cable: Special Communications Modes Control Cable Part #: CBL-DUAL-3 Using two NE-1000 syringe pumps, this cable either creates an automated, continuous operation pumping system, whereby one pump is refilling while the other is dispensing, or creates a dual pumping system, with both pumps operating in the same direction. Plus other special communications modes.
www.SyringePump.com New Era Pump Systems Inc. Model NE-1000 Multi-Phaser™ Pump doesn’t stop after dispensing a set volume: The pump was previously setup with a multiple Phase Pumping Program. To simply dispense a fixed volume at a fixed pumping rate, the second Program Phase must be the ‘Stop’ function. See section 9.1, How to Enter Pumping Programs, for instructions on changing the Pumping Program. Pump stops pumping after a period of time: A dispense target volume has been set.
New Era Pump Systems Inc. www.SyringePump.com Model NE-1000 Multi-Phaser™ 12.7 Syringe Diameters and Rate Limits Syringe Syringe Manufacturer (mL) (all names ™) B-D HSW Norm-Ject Monoject Terumo Poulten & Graf (Glass) Steel Syringes SGE (gas tight) Hamilton Microliter Inside Diameter (mm) Maximum Rate (mL/hr) Minimum Rate (µL/hr) Maximum Rate (mL/min) 1 4.699 53.07 0.73 0.884 3 8.585 177.1 2.434 2.952 5 11.99 345.5 4.748 5.758 10 14.43 500.4 6.876 8.341 20 19.05 872.2 11.99 14.53 30 21.