User Manual
- 2 - 
Overview 
Moxa’s USB-to-serial product provides a wide range of easy-to-use 
solutions for adding Windows COM ports and Linux tty ports through a 
PC’s USB port. 
The UPort 1200/1400/1600 series are the following models: 
•  UPort 1250: 2-port RS-232/422/485 USB-to-serial converter 
•  UPort 1250I: 2-port RS-232/422/485 USB-to-serial converter w/ 
isolation protection 
•  UPort 1410: 4-port RS-232 USB-to-serial converter 
•  UPort 1450: 4-port RS-232/422/485 USB-to-serial converter 
•  UPort 1450I: 4-port RS-232/422/485 USB-to-serial converter w/ 
isolation protection 
•  UPort 1610-8: 8-port RS-232 USB-to-serial converter 
•  UPort 1650-8: 8-port RS-232/422/485 USB-to-serial converter 
•  UPort 1610-16: 16-port RS-232 USB-to-serial converter 
•  UPort 1650-16: 16-port RS-232/422/485 USB-to-serial converter 
Before connecting UPort USB-to-serial converters to your computer’s 
USB port, we recommend installing the UPort driver first. To do this, 
follow the installation procedure described in the “Installing the UPort 
1200/1400/1600 Driver” section below. The installation procedure was 
done on a PC running a Windows platform. UPort converters can be 
connected to any upstream type A USB port that is on the PC host or on 
an upstream hub. UPort converters are hot pluggable, and therefore 
there is no need to power down your computer prior to installation. 
After installing the driver, connect the UPort to an upstream host or 
hub. The Found New Hardware wizard will locate the appropriate 
drivers automatically. Once the drivers are found, various windows will 
pop up as the UPort’s serial port is being installed. When the Found 
New Hardware Wizard finishes installing the UPort, use the operating 
system’s Device Manager to check and/or modify the port settings. 
The new COM port will be listed under Ports (COM & LPT). 
Ordering Information 
Package Checklist 
Before installing the UPort, verify that the package contains the 
following items: 
•  1 UPort 1200/1400/1600 USB-to-serial converter 
•  USB cable: CBL-USBA/B-100 
•  100 to 240 VAC power adapter (excluding T models, UPort 
1250/1410)   
•  1 power cord suitable for your region (excluding T models, UPort 
1250/1410)   
•  1 serial adapter: mini DB9F-to-TB (excluding UPort 1410/1610 
series) 
•  WK-44-01: 19” rackmount L brackets (2 L-shaped plates with 8 
screws; for UPort 1600-16 series) 
•  Quick installation guide (printed) 
•  Warranty card 
NOTE 
Notify your sales representative if any of the above items is 
missing or damaged. 






