Certifications 2

SDS No.: 128186 V002.0
Metylan Ovalit TM
Page 8 of 14
SECTION 11: Toxicological information
General toxicological information:
An allergic reaction cannot be excluded after repeated skin contact.
11.1. Information on toxicological effects
Acute oral toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Value
type
Value
Species
Method
2-methylisothiazol-3(2H)-
one
2682-20-4
LD50
120 mg/kg
rat
EPA OPPTS 870.1100 (Acute Oral Toxicity)
Isothiazolinone mixture
3:1 (CIT/MIT)
55965-84-9
LD50
66 mg/kg
rat
OECD Guideline 401 (Acute Oral Toxicity)
Acute dermal toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Value
type
Value
Species
Method
2-methylisothiazol-3(2H)-
one
2682-20-4
LD50
242 mg/kg
rat
OECD Guideline 402 (Acute Dermal Toxicity)
Isothiazolinone mixture
3:1 (CIT/MIT)
55965-84-9
LD50
87,12 mg/kg
rabbit
OECD Guideline 402 (Acute Dermal Toxicity)
Acute inhalative toxicity:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Value
type
Value
Test atmosphere
Exposure
time
Species
Method
2-methylisothiazol-3(2H)-
one
2682-20-4
LC50
0,11 mg/l
dust/mist
4 h
rat
OECD Guideline 403 (Acute
Inhalation Toxicity)
Isothiazolinone mixture
3:1 (CIT/MIT)
55965-84-9
LC50
0,171 mg/l
dust/mist
4 h
rat
OECD Guideline 403 (Acute
Inhalation Toxicity)
Skin corrosion/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
2-methylisothiazol-3(2H)-
one
2682-20-4
corrosive
4 h
rabbit
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Isothiazolinone mixture
3:1 (CIT/MIT)
55965-84-9
corrosive
4 h
rabbit
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Serious eye damage/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
Isothiazolinone mixture
3:1 (CIT/MIT)
55965-84-9
Category 1
(irreversible
effects on the
eye)
rabbit
not specified