SDS

G178, Perfect Clarity Coating (25-63C) 09/10/14
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Page 10 of 15
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name
Route
Value
Species
Test Result
Exposure
Duration
Hexamethyldisiloxane
Inhalation
Not toxic to female reproduction
Rat
NOAEL 33
mg/l
13 weeks
Hexamethyldisiloxane
Inhalation
Some positive male reproductive data
exist, but the data are not sufficient for
classification
Rat
NOAEL 33
mg/l
13 weeks
1-propoxy-2-propanol
Inhalation
Some positive developmental data exist,
but the data are not sufficient for
classification
Rat
NOAEL 3.6
mg/l
during
organogenesi
s
Stoddard Solvent
Inhalation
Not toxic to development
Rat
NOAEL 2.4
mg/l
during
organogenesi
s
Acetone
Ingestion
Not toxic to female reproduction
Mouse
NOAEL
11,298
mg/kg/day
13 weeks
Acetone
Ingestion
Some positive male reproductive data
exist, but the data are not sufficient for
classification
Rat
NOAEL
1,700
mg/kg/day
13 weeks
Acetone
Inhalation
Some positive developmental data exist,
but the data are not sufficient for
classification
Rat
NOAEL 5.2
mg/l
during
organogenesi
s
Isopropyl Alcohol
Ingestion
Some positive developmental data exist,
but the data are not sufficient for
classification
Rat
NOAEL 400
mg/kg/day
during
organogenesi
s
Isopropyl Alcohol
Inhalation
Some positive developmental data exist,
but the data are not sufficient for
classification
Rat
LOAEL 9
mg/l
during
gestation
Petroleum Distillates
Inhalation
Not toxic to development
Rat
NOAEL 2.4
mg/l
during
organogenesi
s
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name
Route
Target Organ(s)
Value
Species
Test Result
Exposure
Duration
Hexamethyldisiloxane
Inhalation
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
Rat
NOAEL 33
mg/l
6 hours
Hexamethyldisiloxane
Ingestion
central nervous
system depression
Some positive data exist, but the
data are not sufficient for
classification
Guinea
pig
LOAEL
22,900 mg/kg
not applicable
1-propoxy-2-propanol
Inhalation
central nervous
system depression
May cause drowsiness or
dizziness
Multiple
animal
species
LOAEL 10.8
mg/l
6 hours
1-propoxy-2-propanol
Inhalation
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
NOAEL Not
available
1-propoxy-2-propanol
Ingestion
central nervous
system depression
May cause drowsiness or
dizziness
Rat
LOAEL
1,770 mg/kg
not applicable
Stoddard Solvent
Inhalation
central nervous
system depression
May cause drowsiness or
dizziness
Human
and
animal
NOAEL Not
available
Stoddard Solvent
Inhalation
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
NOAEL Not
available
Stoddard Solvent
Inhalation
nervous system
Some positive data exist, but the
data are not sufficient for
classification
Dog
NOAEL 6.5
mg/l
4 hours
Acetone
Inhalation
central nervous
system depression
May cause drowsiness or
dizziness
Human
NOAEL Not
available