User's Manual

Pump implantation
56
Rinse the Pump with insulin (IN1)
1. Remove the second refill syringe from the refill kit package.
2. Firmly attach the two-way stopcock to the refill syringe and attach an 18
gauge needle to the stopcock. Use the sterile marker to label the syringe,
“IN1”.
3. Draw 20 mL of INSULIN (two vials) into the refill syringe.
4. Remove the 18 gauge needle and expel all air bubbles in the syringe.
5. Close the stopcock.
6. Retract the plunger until it locks into place. This should be no further than 55
mL. Do not go beyond the vent hole. Press the lock into the plunger groove to
be sure it is firmly secured.
7. Shake vigorously for a minimum of 30 seconds to degas the INSULIN.
8. Point the syringe tip upward and slowly open the stopcock to vent the
syringe.
9. Release the locking ring on the refill syringe.
10. Expel air in the syringe and carefully observe to ensure no air bubbles remain
in the syringe. If air bubbles are noted, repeat steps 5-10.
11. Fill the hub of the refill needle with INSULIN and attach it to the stopcock.
12. Prime the needle and close the stopcock.
13. Refill the fill port with the 3 mL RINSE BUFFER syringe, as needed, to
maintain the fluid barrier.
14. Use the “IN1” syringe containing the degassed INSULIN to fill the Pump.
OPTIONAL
Use these steps only if the plunger is not moving forward while filling the reser-
voir.
1. With the refill needle pointing down, vent the syringe head space by pulling
back firmly on the plunger until the second sealing ring on the black rubber
cap passes beyond the vent hole (see Figure 7).