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Background
Before the introduction of silicones, most moisture barriers
consisted predominately of petrolatum and were occlusive.
Occlusive products suppress barrier recovery and reduce
the epidermal proliferative response to an abnormal
stratum corneum barrier.
1
Objectives
1. To determine the wash-off resistance rates of
Nutrashield, a semi-occlusive moisture barrier
consisting of silicone blends.
2. To determine the moisture vapor transmission
rates (MVTR) of the specific barrier, proving it
prevents e-TEWL.
Methodology
To determine wash-off resistance, the test area was
cleansed, dried and a background spectrum collected.
A 0.1 gram sample of Nutrashield and competitive
barriers were then placed on the test area and rubbed in
for 30 seconds. A spectrum was collected after drying. After
30 minutes, the test area was rinsed. Lather was applied
and the test area rubbed lightly 15 times, then again rinsed,
patted dry, and a spectrum collected. Every 30 minutes, a
new wash cycle was repeated until 5 cycles were completed.
The MVTR test protocol was performed by treating collagen
with Nutrashield. Each treated collagen sheet was then
placed over a Fisher Payne Permeability Cup containing 3
grams of water. Each cup was then placed in a 37° Celsius
oven and measured for weight loss over a 24-hour period.
Results
1. Medline Nutrashield outperformed all other
products tested by surviving five wash cycles
over a period of 3 hours.
2. Nutrashield greatly reduces moisture vapor loss by
65% as compared to the control.
Impact
Nutrashield, a silicone-based barrier, proved to be an
exceptional moisture barrier while remaining breathable.
Occlusion of the skin helps to increase the risk of infection
and may decrease the protection of the skin’s normal pH,
therefore it should be avoided if possible.
* Adapted from the original study
Protect
Nourish
Protect
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0
50
100
150
200
Remedy
Nutrashield
Sensi-CareSween
®
24
Proshield
®
Plus
Wash-off Resistance Results
(time)
Durability (in minutes)
0
1
2
3
4
5
Remedy
Nutrashield
Sween 24Proshield Plus
Number of Washes
Wash-off Resistance Results
(washes)
Nutrashield offers long-lasting protection
Nutrashield stays in place for longer
periods of time and doesn’t need to be
reapplied as often as other products.
Data on file
Clinically Tested to be:
• CHG Compatible
• Latex-Friendly
• Non-Cytotoxic
• Non-Sensitizing
• Non-Irritating
• Non-Allergenic
Dermatologist Tested
Comparative Study of Medline Nutrashield
For Wash-off Resistance
Prepared by Dow Corning Corporation. 2005.
Nourish
1. Aly R, Shirley C, Cunico B, Maibach H, Effect of
prolonged occlusion on the microbial flora, pH, carbon
dioxide and transepidermal water loss on human skin. J
Invest Dermatol. 1978;71:378-381.
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