Manual

ManualsBrandsMartin Christ ManualsEquipmentEpsilon 2-6D LSCplus

Operating Manual

Freeze-dryer

EPSILON 2-6 LSCplus

Part no. 113100, 113120

Translation of the original operating manual

Version 10/2012

Rev. 1.6 of 16/12/2014

EPSILON 2-6 LSCplus; ;

Summary of content (135 pages)

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Operating Manual Freeze-dryer EPSILON 2-6 LSCplus Part no. 113100, 113120 Translation of the original operating manual sb Version 10/2012 Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus In case of inquiries, please state the following numbers: Order number Serial number © Copyright by Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode am Harz Germany Tel.: +49 (0) 5522 / 5007-0 Fax: +49 (0) 5522 / 5007-12 Web: www.martinchrist.de E-mail: info@martinchrist.de Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus Table of contents 1 General information ............................................................................................................. 9 1.1 Importance of the operating manual.................................................................................. 9 1.2 Intended use ..................................................................................................................... 9 1.3 Warranty and liability..................................
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Freeze-dryer EPSILON 2-6 LSCplus Table of contents 4 Storage and transport ....................................................................................................... 31 4.1 Dimensions and weight ................................................................................................... 31 4.2 Storage conditions .......................................................................................................... 31 4.3 Notes on transport ......................................
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Freeze-dryer EPSILON 2-6 LSCplus Table of contents 7 Malfunctions and error correction .................................................................................... 88 7.1 General malfunctions ...................................................................................................... 88 7.1.1 Power failure.............................................................................................................. 89 7.1.2 Insufficient vacuum .............................................
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Freeze-dryer EPSILON 2-6 LSCplus Table of contents 8 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 1 General information Pos: 1 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n/01 0 Allge mein e In for matio nen == == === == == === == == == === == == === == @ 24 \mo d_1 404 983 207 982_ 68. docx @ 18 2921 @ 1 @ 1 1 General information Pos: 2 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n/01 0-0 010 Stelle nwert de r Betri ebsa nleitu ng @ 25\ mod _14 049 832 092 48_6 8.
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Freeze-dryer EPSILON 2-6 LSCplus 1 General information Pos: 6 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n/01 0-0 030 Gew ährl eistun g u nd Ha ftun g @ 2 5\m od_ 140 498 321 137 7_68 .docx @ 1 829 63 @ 2 @ 1 1.3 Warranty and liability The warranty and liability are subject to our "General Terms and Conditions" that were distributed to the operator upon the conclusion of the contract.
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Freeze-dryer EPSILON 2-6 LSCplus 1 General information Pos: 14 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon 2- 6D LSCplu s Stan dar d/01 0 Allge mein e Inf orm atio nen/ 010 -00 70 Liefe ru mfan g E2- 6D @ 25\ mod _14 0498 478 786 8_6 8.do cx @ 1 861 69 @ 2 @ 1 1.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation Pos: 17 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 Aufb au u nd Wir kung sweise == === == == === == == === == == === = @ 25\ mod _14 049 832 3599 4_6 8.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation 9 Option: Precision control needle valve for air injection 10 Pressure control valve Fig. 3: Detailed view B - vacuum pump 11 Mains switch 12 Steerable castors Fig. 4: Right side of the freeze-dryer Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation 13 Sight glass of the ice condenser 14 Aeration valve 15 Vacuum sensor (behind the side panel 16 Access flange DN40 (e.g. for weighing device, behind the side panel) 17 Media drain valve 18 Fixed castors Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation Water-cooled freeze-dryer: 29 Cooling water connection (see detailed view) Fig. 7: Rear view of a water-cooled freeze-dryer 30 Connector for the cooling water outlet 31 Connector for the cooling water inlet Fig. 8: Detailed view C cooling water connections Pos: 20 / 010 Unive rsalm odul e/Seite nwechs el @ 0 \mo d_1 202 116 244 312_ 0.d ocx @ 105 @ @ 1 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation Pos: 21 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon 2- 6D LSCplu s Stan dar d/02 0 Aufb au und Wi rkun gsweise /020 -0 010 -002 0 Typ enschild E2-6D @ 2 5\m od_ 1404 984 799 912 _68. docx @ 18 619 7 @ 3 @ 1 2.1.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation Pos: 23 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 -00 20 Wi rkun gsweise -- --- --- -- --- -- --- -- --- - @ 25\m od_ 140 498 325 385 0_6 8.docx @ 1 830 47 @ 2 @ 1 2.2 Mode of operation Pos: 24 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise/ 020 -00 20- 001 0 G efrie rtr ocknu ng allgem ein @ 25\ mod _14 049 832 548 15_ 68.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation Melting point pressure curve Pressure (mbar) SOLID A Melting B Sublimation 0.37 mbar V Su apo bl ur im p at res io s n ur pr e es cu su rv re e f cu or rv ice e = 6.11 mbar LIQUID ou Vap r ssu pre e urv re c Evaporation Triple point GASEOUS -30°C Temperature (°C) Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation Pressure (mbar) 1 bar LIQUID Melting point pressure curve 1 SOLID cur ve Triple point Va p su ou bl r p im re at ss io ur n e pr cu es rv su e re for cu ic rv e = e 2 ou Vap ur e ess r pr GASEOUS 20°C Temperature (°C) Fig. 11: Freeze-drying phases Please find further information about basic principles, optimum procedures and applications in the brochure "Smart freeze-drying", which can be downloaded at www.martinchrist.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation At the same time, the ice condenser is pre-cooled ("cool-down"). The ice condenser temperature does not have any influence on the product temperature. The sole purpose of the ice condenser is to bind the released water vapour. Pos: 29 / 010 Unive rsalm odul e/Le erzeil e @ 0\mo d_1 202 116 244 500 _0.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation NOTE If the product that is to be dried contains solvents or high salt concentrations, it may start to thaw during the drying process, which is indicated by clearly visible foaming. In order to prevent this, the product must be frozen as deeply as possible, e.g. with the aid of liquid nitrogen, prior to putting it into the unit. Pos: 31 / 010 Unive rsalm odul e/Le erzeil e @ 0\mo d_1 202 116 244 500 _0.
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Freeze-dryer EPSILON 2-6 LSCplus 2 Layout and mode of operation 2.2.2.5 End of drying and aeration The end of the drying process is reached when both the product and shelf temperature are clearly in the positive range (+15 to +20°C) and if their difference is not greater than 5 K. Another indication of the end of the drying process is the behaviour of the vacuum and of the ice condenser temperature.
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 41 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 Siche rheit == === == == === == == == === == == === == == === @ 2 5\m od_ 1404 983 296 098 _68. docx @ 18 320 1 @ 1 @ 1 3 Safety Pos: 42 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 10 B eschilde ru ng d es Ge räts @ 2 5\mo d_1 404 983 297 040 _68. docx @ 18 321 5 @ 2 @ 1 3.
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 44 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 20 Sy mbol - un d Hinw eiserkl äru nge n @ 2 5\m od_ 140 498 3298 133 _68 .docx @ 1 8322 9 @ 2 @ 1 3.2 Explanation of the symbols and notes This operating manual uses the following names and symbols to indicate hazards: This symbol stands for a direct hazard to the life and health of persons.
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 46 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 30 V era ntwor tun g des Betr eiber s @ 2 5\m od_ 140 498 3299 227 _68 .docx @ 1 8324 3 @ 2 @ 1 3.3 Responsibility of the operator The operator is responsible to authorise only qualified personnel to work on the freeze-dryer (see chapter 3.4 - "Operating personnel").
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 52 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 60 Sic her heitshi nweise ++ +++ ++ ++ +++ ++ ++ +++ ++ ++ ++ +++ + @ 25\ mod _14 0498 330 236 1_6 8.do cx @ 1 832 85 @ 2 @ 1 3.6 Safety instructions The following instructions must be observed prior to every drying process: • • WARNING • • • • • Ensure that the freeze-dryer was set up and connected properly (see chapter 5 - "Set-up and connection").
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 57 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 60- 002 0 Mech anisch e Siche rheit @ 25 \mo d_1 404 983 304 593 _68. docx @ 18 331 3 @ 3 @ 1 3.6.2 Mechanical safety In order to ensure the safe operation of the freeze-dryer, please comply with the following points: • • • WARNING • • • • • • • Do not use the freeze-dryer if it was installed incorrectly. Do not use the freeze-dryer without panels.
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 62 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 60- 003 0 Br andsc hutz @ 25 \mo d_1 404 983 3057 08_ 68. docx @ 18 3327 @ 3 @ 1 3.6.3 Fire prevention Fuses protect certain electrical circuits within the freeze-dryer against overcurrent conditions. • • • DANGER Always use fuses of the same type and rating. Do not dry explosive or inflammable substances.
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 70 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 70 Sic her heitsei nricht ung en- -- --- -- --- --- -- --- -- --- -- --- --- -- --- -- --- --- -- --- -- -- @ 25\ mod _14 049 833 091 10_6 8.d ocx @ 183 369 @ 2 @ 1 3.7 Safety devices Pos: 71 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 70- 001 0 Syst emko ntr olle LSCpl us @ 2 5\m od_ 140 498 331 0307 _68 .
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Freeze-dryer EPSILON 2-6 LSCplus 3 Safety Pos: 75 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 90 R estrisik en @ 25\ mod _14 049 833 155 77_ 68.d ocx @ 183 453 @ 2 @ 1 3.9 Remaining hazards All CHRIST freeze-dryers were built state-of-the-art and according to the accepted safety rules.
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Freeze-dryer EPSILON 2-6 LSCplus 4 Storage and transport Pos: 78 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /04 0 La ger ung und Tr ans port /040 L age run g un d T rans por t= === == == === == == === == == === == @ 2 5\mo d_1 404 983 713 664 _68.
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Freeze-dryer EPSILON 2-6 LSCplus 4 Storage and transport 4.4 Packaging The freeze-dryer is packaged in a wooden crate. • After opening the packaging, take out the accessories. • Remove the packaging material. • Remove the side walls of the crate. • Lift the freeze-dryer upwards with a lifting device. Always reach under the freeze-dryer from the front side (A). The freeze-dryer Epsilon 2-6D LSCplus weighs approx.
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Freeze-dryer EPSILON 2-6 LSCplus 4 Storage and transport Pos: 87 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon Stan dar d/04 0 La ger ung un d T rans por t/04 0-0 050 T rans por tsiche run gen E psilon @ 25\ mo d_14 049 846 137 92_ 68.d ocx @ 185 637 @ 2 @ 1 4.5 Transport safety devices The following transport safety devices must be removed prior to start-up: • Remove the polystyrene blocks between the shelves.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Pos: 92 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /05 0 Aufstell ung und Anschlus s/05 0 Aufs tellun g u nd Ansc hluss= == == === == == === == == == === == @ 25 \mo d_1 404 983 7372 44_ 68. docx @ 18 3495 @ 1 @ 1 5 Set-up and connection Pos: 93 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /05 0 Aufstell ung und Anschlus s/05 0-0 011 Aufst ellort (Epsilon ) @ 25\ mod _14 049 8373 912 9_6 8.d ocx @ 1835 23 @ 2 @ 1 5.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Pos: 100 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 50 Aufs tellun g u nd Ansc hluss/0 50- 003 0 Tro ckne rpat ron e (Ad sor ptionsfilt er ) - Ü bersc hrift -- --- -- --- --- -- --- -- --- -- --- - @ 26\m od_ 140 505 799 428 5_68 .docx @ 1 909 60 @ 2 @ 1 5.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Pos: 103 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 50 Aufs tellun g u nd Ansc hluss/0 50- 004 0 Vak uu mmess sond e - Übe rschrif t-- -- --- -- --- --- -- --- -- --- --- -- --- @ 2 6\m od_ 1405 058 078 325 _68. docx @ 19 098 7 @ 2 @ 1 5.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Thyracont VSP62/63 MKS 722B Pfeiffer TPR 280/281 Fig. 19: Installed vacuum sensors of different manufacturers The vacuum sensor comes supplied in a calibrated state. NOTE After power-on, the vacuum sensor needs a few minutes to reach its operating temperature. Pos: 105 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Fig. 20: Example of a door locking system of the loading door; here: door stop (left side) Pos: 108 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0. docx @ 11 4 @ @ 1 Pos: 109 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 50 Aufs tellun g u nd Ansc hluss0 50- 006 0 Belüf tun gsventil E psilon @ 25\ mo d_1 4049 846 327 70_ 68.d ocx @ 185 777 @ 2 @ 1 5.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Pos: 111 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 50 Aufs tellun g u nd Ansc hluss/0 50- 007 0 Medi ena blaufv entil Epsilo n @ 25\ mod _140 498 463 389 8_6 8.doc x @ 1 857 91 @ 2 @ 1 5.7 Media drain valve The media drain valve is located at the bottom of the left side of the unit (see chapter 2.1.1 - "Functional and operating elements"). It is used to drain off the condensate and the defrosting water.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Pos: 117 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 50 Aufs tellun g u nd Ansc hluss/0 50- 009 0 D ruckst eue rven til Epsilon (au ße r 2 -4) @ 25 \mo d_1 404 984 6375 31_ 68. docx @ 18 5833 @ 2 @ 1 5.10 Pressure control valve The pressure control valve is integrated in the suction pipe between the vacuum pump and ice condenser chamber.
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Freeze-dryer EPSILON 2-6 LSCplus 5 Set-up and connection Pos: 119 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 50 Aufst ellun g un d Anschl uss/0 50- 010 0 G um miventil e @ 2 5\m od_ 140 498 3741 840 _68 .docx @ 1 8356 5 @ 2 @ 1 5.11 Rubber valves The rubber valves (part no. 121860) enable the connection of round-bottom flasks, wide-neck filter bottles, or distributors for ampoules to a manifold or drying chamber. Depending on the connector of the components, the blue plug can be removed.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Pos: 122 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ 060 B etrie b= === == == === == == === == == === == == == === == == == @ 25\ mod _14 049 837 597 58_6 8.d ocx @ 183 578 @ 1 @ 1 6 Operation Pos: 123 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ 060 -00 10 E rste I nbe trie bnah me ++ +++ ++ ++ +++ ++ ++ +++ ++ ++ ++ + @ 2 5\m od_ 140 4983 760 674 _68. docx @ 18 359 2 @ 2 @ 1 6.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Pos: 131 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50 LSCplus Anl age nsteu eru ng Epsil on - -- --- -- --- --- -- --- -- --- --- -- --- -- --- -- --- --- @ 2 5\m od_ 1404 983 956 815 _68. docx @ 18 369 0 @ 2 @ 1 6.5 LSCplus control system The control system LSCplus (Lyo Screen Control plus) was specifically developed for the control of freeze-drying processes.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation The user interface is divided into four main windows that can be called up by touching the corresponding buttons: Manual This window is also the standard user interface. It is used to control the freeze-drying process manually. Program This area is used to create and execute programs for automating the freeze-drying process and for making it reproducible. This function is only available in combination with the programmer module PGMplus option.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Status line (1) This line shows the operating status of the freeze-dryer as well as the active phase. The status line also shows the current date and time. The clock is batterybuffered and must be reset after a failure (see chapter 6.5.1.3 - "Main window "Options"", section "Administration"). In addition, the drive symbol provides information concerning the status of the external data storage device or of the network drive. The following symbols are possible: ..
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Actual values of the current process (4) This area shows the current process data. The fields can be configured as desired: • Select the button of the field that is to be adapted. A dialog box opens: Fig. 27: Dialog box "Select actual value" • Select the desired configuration or quit the dialog box by pressing the "return" button. In this way, it is possible to configure a personalised overview of the actual values.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Option: USB process recording (see chapter 6.6 - "Optional extensions and special equipment") • Select the "Process recording" function in the dialog box "Tools". • Select the input fields ("Batch data"). A keyboard for the data input will be displayed. • If necessary, select the “Options” tab, choose between manual or automatic recording, and define a recording interval. • Press the "return" button in order to close the dialog box.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Fig. 30: Dialog box "Pressure increase test" • The "Test stop" button stops the pressure increase test. Option: LyoBalance weighing system If the freeze-dryer is equipped with a LyoBalance weighing system (see chapter 6.6 - "Optional extensions and special equipment"), then the corresponding parameters must be configured in this dialog box.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Dialog box "Process and equipment messages" (7) This dialog box shows and saves all of the error messages and other messages. In the event of an error or message, the window “Process and equipment messages” will open automatically. In addition, a sound signal is emitted until the error is acknowledged.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Details Touching the message calls up details concerning the error message: • Cause of the message, • Effects of the message, • Measures to eliminate the error, • Reference designator, • Error counter (indicates how often this error has occurred) and the time stamp of the last error message. Use the arrow keys to call up the individual windows. The error message text is always followed by an error code.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Dialog box "Operating mode: select/start" (8) After the set values have been entered for the process, the process can be started manually with this function (see chapter 6.5.2 - "Manual freezedrying"). Fig. 35: Dialog box "Operating mode: select/start" (The version of the dialog box that is displayed depends on the equipment of the freeze-dryer.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Pos: 137 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50- 001 0-0 021 Hau ptfe nster Prog ra mm Epsil on @ 25\ mod _14 049 839 6583 4_6 8.d ocx @ 183 788 @ 4 @ 1 6.5.1.2 Main window "Program" In the main window "Program", pre-programmed freeze-drying processes can be loaded and edited and new programs can be created with the PGMplus programmer module. 1 2 3 Program list Button "New program" Buttons "Load" Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Pos: 139 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50- 001 0-0 031 Hau ptfe nster Opti one n Epsilon - 1 Vakuu mpu mp e @ 2 5\m od_ 140 498 3968 681 _68 .docx @ 1 8381 6 @ 4 @ 1 6.5.1.3 Main window "Options" The main window "Options" is used to perform fundamental basic settings of the control system in order to adapt it perfectly to the respective area of application of the freeze-dryer.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Change scale unit (2) This dialog box is used to change the unit of measurement for the temperature and vacuum. Fig. 39: Dialog box "Change scale unit" Special equipment: Preselection of the aeration medium (3) This function can be performed in the manual mode or saved together with a program (see chapter 6.5.3.1 - "Creating a program").
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation The following media preselection settings are possible: • Air: Preselects the media connection "Air". • Inert gas: Preselects the media connection "Inert Gas". • Automatic: Automatic media connection preselection depending on the chamber pressure and stoppering status of the product vials: – Chamber pressure 950 mbar: Preselection of the media connection "Air". – Chamber pressure < 950 mbar: Preselection of the media connection "Inert gas".
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Special equipment: Inertisation (5) (see chapter 6.6 - "Optional extensions and special equipment") In order to start an inertisation process, all of the aeration ports must be connected to the inert gas supply. The aeration valves are disabled during an active inertisation process.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Administration “Administration” options: 1 "Date/Time" 2 "Network" 3 "System properties" 4 "Access protection" 5 "Device options" 6 "Configuration of sensors" 7 "WTMplus configuration" Fig. 43: Dialog box "Options/Administration" Date/Time (1) The LSCplus control system is equipped with an integrated, batterybuffered clock. After a failure of the buffer battery, the date and time must be reset. Fig. 44: Dialog box “Change date/time Version 10/2012, Rev.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Network (2) This dialog box is used to change various system settings. The modifications will not become effective until after a restart of the unit. NOTE Fig. 45: Dialog box "Network" System properties (3) This dialog box is used to change various system settings. Fig. 46: Dialog box "System properties" Beeper: The beeper sounds in the event of a malfunction, for example.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Click on touch: If this function is active, a clicking sound can be heard whenever the system registers that a button has been touched.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation • The button with the lock symbol blocks the access immediately and the system switches to the default setting. Fig. 49: Access blocked, the data cannot be edited Operator/maintenance/administrator password: For each of these access levels, certain editing rights have been defined.They can be enabled with the corresponding password. The rights of the various access levels are detailed in the following table.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation If the freeze-dryer is to be extended by an option, this option must be enabled via this dialog box. • Press the button "Add option". An input window opens. • Enter the six-digit Christ activation code that was supplied for this option. Note that the keys are case sensitive. Options can be removed in the same way. The modifications will not become effective until after a restart of the unit.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation WTMplus configuration (7) The dialog box is displayed for information purposes only. The configuration can be changed only via the LPCplus user interface. NOTE This dialog box shows all of the existing WTMplus sensors. Every sensor is assigned to a measuring channel based on its serial number. Next to the Number of the measuring channel and the serial number of the sensor, the associated temperature and a signal quality index (SQI) are displayed.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Service “Service” options: 1 "Operating hours" 2 "Failure memory" 3 "Vacuum pump oil change" 4 "Maintenance" 5 "Sensor adjustment" Fig. 53: Dialog box "Service" (varies depending on the type of system) Operating hours (1) This dialog box is used to call up the number of operating hours of the various components of the freeze-dryer, e.g. the refrigeration unit, vacuum pump, or pressure control valve.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Failure memory (2) The failure memory stores the most recent messages of the process and equipment information system. These messages can be viewed in this dialog box. The failure memory includes the last 32 messages. If this number is exceeded, the oldest message will be overwritten. Use the arrow keys to call up the individual messages. The error message text is always followed by an error code.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Fig. 56: Dialog box "Vacuum pump oil change" Maintenance (5) The maintenance interval of the unit is fixed at 3,000 operating hours or at least one maintenance per year. When the end of a maintenance interval is reached, a corresponding message will be displayed. • Acknowledge the message. • Make an appointment for the maintenance of your freeze-dryer.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Sensor adjustment (6) Misadjusted sensors will lead to incorrect measurement values, which in turn will have a negative effect on the process control. CAUTION In this dialog box, the sensors are adjusted in terms of a predefined reference value. • Press the button in order to select the sensor. A selection menu will be displayed. • Enter a reference value and press the button "Adjust". Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Pos: 141 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50- 001 0-0 041 Hau ptfe nster "? " Epsilo n @ 25\ mod_ 140 498 397 319 3_6 8.doc x @ 1 838 58 @ 4 @ 1 6.5.1.4 Main window "?" This main window includes the most important information concerning your freeze-dryer: 1 2 3 4 Freeze-dryer type Control system type Serial number Manufacturer contact data 5 Details concerning the software version Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation In the manual mode, the set values of the active phase can be changed during the process run. In this case, the control system adapts the unit to the new set values as quickly as possible. After the completion of a phase, the system switches to the next phase without switching the unit to standby. The transition from "freezing" to "warm-up" takes place automatically. After the completion of the warm-up phase, this dialog box will be displayed: Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Viewing or editing the set values: • Press the button "Set values: view/edit" (see chapter 6.5.1.1 - "Main window "Manual""). The following dialog box will be displayed: 1 2 "Aeration" button "Defrosting" button 3 "Media drain" button (special equipment) "Leakage test" button 4 Fig. 61: Dialog box "Set values: view/edit" Fields that are displayed in the form of buttons can be edited.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Numerical values can be edited with the aid of a numerical keypad: 1 2 Set value display Button for changing the sign (e.g. when entering temperature values) 3 4 " " (infinite) Button for editing the value in pre-defined steps 5 Selection of a possible maximum or minimum value 7 Input of a value via the numerical keypad Button for deleting the displayed value Fig.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Program sections When the programmer module executes a freeze-drying process, it executes the various sections that were created one after the other until the last section is completed. Within the various sections, the system calculates linear ramps for the temperature and vacuum.These ramps start with the set value of the previous section and end with the set value of the current section.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation T shelf: This value defines the permissible deviation of the shelf temperature from the set value. At the end of the section, the actual temperature of the shelves (in the case of WST shelf 1) will be compared to the set value. If the shelf temperature is beyond the permissible range, the section will be extended until the deviation is within the permissible range.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation +30 T/°C Pressure/mbar +20 +10 Section “freezing” Last section “freezing” 100 10 First section “drying” 1 0.1 0 -10 0.01 -20 0.001 t/h Warm-up phase of the vacuum pump Fig. 65: The warm-up phase of the vacuum pump is shifted to the freezing phase prior to the first drying section Pos: 150 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Creating a blank program (1) This button is used to call up a blank program template. Only section 1 is pre-defined as the loading section. In this phase, the start conditions of the programs are defined. The room temperature (20°C) is the standard default. If the product is frozen outside the freeze-dryer (double-chamber method), the shelf temperature must be adapted accordingly in section 1.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation • Pressing the button “Program name” (2) calls up an input field in which the name of the program can be changed. • The button “Save” (7) can be used in between or at the end of the program creation in order to save the program. • The button “Program” (1) calls up the main window. The system will ask the user whether the program shall be saved if this has not been done yet. The program will be automatically assigned to the first free program storage location.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation • • • • 76 Periodic pressure increase test: The test will be performed periodically during the entire main or final drying phase. The parameters "Duration test" and "Time between tests" apply. The maximum pressure increase is limited to 100%, referring to the actual value at the beginning of the measurement. If the value is exceeded, the pressure increase test will be aborted in order to prevent the product from thawing.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Fig. 69: Dialog box "Pressure increase test" in the program mode Option: Comparative pressure measurement (see chapter 6.6 - "Optional extensions and special equipment") The indication of the measurement value "dp Comp" can be configured in chapter 6.5.1.1 - "Main window "Manual"" under "Actual values of the current process" in the dialog box "Select actual value".
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Fig. 70: Dialog box "Comparative pressure measurement" Option: LyoBalance weighing system If the freeze-dryer is equipped with a LyoBalance weighing system (see chapter 6.6 - "Optional extensions and special equipment"), then the corresponding parameters must be configured in this dialog box. Please refer to the separate operating instructions of the weighing system! NOTE Option: Aeration, stoppering, storage (see chapter 6.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Repeated pressing of this button enables the user to choose between the following variants: • Deactivated • Aeration (up to the "Aeration" value) and subsequent storage • Stoppering (at drying vacuum followed by aeration up to atmospheric pressure) with subsequent storage • Aeration (up to the "Aeration" value), stoppering (followed by aeration up to atmospheric pressure) with subsequent storage The set values of the parameters can be adapted by way of the respe
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Parameter No. Value range Default setting Aeration 2 100 mbar…1000 mbar 500 mbar Aeration after stoppering 3 100 mbar…1000 mbar 500 mbar Stoppering 4 1 sec….999 sec 10 Storage 5 -99.9°C…99.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Special equipment: Gas injection with a proportional valve (4) see (see chapter 6.5.1.3 - "Main window "Options""), section "Special equipment: Gas injection with a proportional valve" Program templates (2) The PGMplus programmer module offers various program templates that include recipes for all kinds of freeze-drying applications. They are suggestions for orientation purposes and must be adapted to the specific area of application of the freeze-dryer.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation 6.5.3.2 Editing a program An existing program can be modified as long as it has not been loaded. • Select the program to be edited from the list in the main window “Program”. • Press the button with the program name in order to call up a window that displays the program data. • Perform the desired modifications and save the program (see chapter 6.5.3.1 - "Creating a program"). • Close the dialog box by pressing the “Program” button.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Fig. 74: Dialog box "Load program" • • Press the button "Load" in order to accept the program data. The display switches to the standard user interface. Press the button "Program start" in order to start the freeze-drying process. Fig. 75: The freeze-drying process can be started with the aid of the button “Program start”.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation 6.5.3.5 Deleting a program The PGMplus programmer module offers 32 program storage locations. If they are all occupied, a program must be deleted before a new one can be created. • Select the program to be deleted from the list in the main window "Program". • Press the button with the program name in order to call up a window with the program data. • Press the button “Delete program”. The system will then display a dialog box with an enquiry.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation Pos: 162 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 60 Optio nale Erw eite run gen und S onde ra usstatt ung en Epsil on- --- -- --- -- --- --- -- --- -- --- --- -- @ 25 \mo d_1 404 984 006 843_ 68. docx @ 18 4054 @ 2 @ 1 6.6 Optional extensions and special equipment Aeration, stoppering, storage see also chapter 6.5.3.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation USB process recording see also chapter 6.5.2 - "Manual freeze-drying", section "Dialog box "Tools"" This feature enables the recording of a running process on a USB storage medium. After the end of the process recording, the process data can be viewed on the PC with LyoLogplus and they can be printed. It is also possible to import the data directly into an Excel file. Preselection of the aeration medium see also chapter 6.5.1.
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Freeze-dryer EPSILON 2-6 LSCplus 6 Operation LPCplus SCADA system The Christ LPCplus system consists of the Supervisory Control And Data Acquisition (SCADA) software program by Martin Christ Gefriertrocknungsanlagen GmbH and a dedicated PC. The system is connected to the LSCplus controller of the freeze-dryer via Ethernet and provides the operation of all of the freeze-drying functions as well as process recording (measurement data and process events), process documentation and data backup.
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Freeze-dryer EPSILON 2-6 LSCplus 7 Malfunctions and error correction Pos: 169 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche /07 0 Stö run gen und Fe hlers uche == == === == == === == == === == == == @ 25\ mo d_14 049 840 560 39_ 68.d ocx @ 184 111 @ 1 @ 1 7 Malfunctions and error correction Malfunctions are displayed in the dialog box "Process & equipment messages" (see chapter 7.2 - "Process and error messages").
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Freeze-dryer EPSILON 2-6 LSCplus 7 Malfunctions and error correction Type of error Possible reason Correction The displayed vacuum value is not correct • Incorrect calibration • • The vacuum sensor is soiled (e.g. due to water residues). The vacuum sensor is defective. • • • Calibrate the vacuum sensor (see the separate operating instructions of the vacuum sensor). Clean the vacuum sensor. Check the vacuum display with the aid of a reference device (if available). • see chapter 7.1.2.
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Freeze-dryer EPSILON 2-6 LSCplus 7 Malfunctions and error correction Pos: 176 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche /07 0-0 010 -00 20 Kei n au sreic hend es Vak uum @ 2 5\mo d_1 404 984 060 039 _68. docx @ 18 416 7 @ 3 @ 1 7.1.2 Insufficient vacuum The vacuum checks must be carried out when the ice condenser is frozen. NOTE Pos: 177 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer EPSILON 2-6 LSCplus 7 Malfunctions and error correction 7.1.2.2 Aeration valve, media drain valve A malfunction of the aeration valve or the media drain valve may have several causes. One potential source are contaminants such as product residues within the valve. • Switch the freeze-dryer off and disconnect the mains plug. • Clean the valve (see chapter 8.1.1.3 - "Aeration valve, media drain valve"). • Put the freeze-dryer into operation again.
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Freeze-dryer EPSILON 2-6 LSCplus 7 Malfunctions and error correction Pos: 188 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 70 Stö run gen und Fe hler such e/07 0-0 010 -00 31 Eisko nde nsat or- und Stellfläc hent emp era tur E psilon @ 25\ mo d_1 4049 846 659 83_ 68.d ocx @ 185 861 @ 3 @ 1 7.1.3 Insufficient ice condenser temperature Ensure sufficient ventilation.
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Freeze-dryer EPSILON 2-6 LSCplus 7 Malfunctions and error correction Pos: 192 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche /07 0-0 031 Kont akt im S ervice fall_Epsilo n @ 25\m od_ 140 498 406 970 5_68 .docx @ 1 842 93 @ 2 @ 1 7.3 Service contact In the event of queries, malfunctions, or spare part enquiries: From Germany: Contact Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode (Germany) Tel.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 195 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 Wa rtun g un d Ins tan dhalt ung == === == == === == == === == == == == @ 25\ mod _14 049 840 9570 4_6 8.d ocx @ 184 307 @ 1 @ 1 8 Maintenance and service The freeze-dryer and the accessories are subject to high mechanical stress. Thorough maintenance performed by the user extends the service life and prevents premature failure.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 200 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 10- 001 0-0 010 Eiskon dens ato rkam me r (a uß er Epsil on 2 -4) @ 2 5\m od_ 1404 984 098 898 _68. docx @ 18 434 9 @ 4 @ 1 8.1.1.1 Ice condenser chamber Before each start-up, ensure that the ice condenser chamber is free from water residues. • Open the media drain valve to drain off any liquid. Then, close the valve.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 204 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 10- 001 0-0 030 Belüf tung sventil, Me dien ablau fventil LSCplus (au ße r Epsilon 2- 4) @ 25\ mod _14 049 841 011 41_ 68.d ocx @ 184 377 @ 4 @ 1 8.1.1.3 1 2 3 Aeration valve, media drain valve Contaminants such as product residues may lead to an insufficient vacuum.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 208 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 10- 002 0 Vak uum pu mpe @ 25 \mo d_1 404 984 1034 28_ 68. docx @ 18 4405 @ 3 @ 1 8.1.2 Vacuum pump Please refer to the separate operating manual of the vacuum pump! NOTE The stress of the vacuum pump in conjunction with a freeze-dryer is usually not very high.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 212 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 10- 004 0 Vak uum mess sond e @ 25\ mod _14 0498 410 561 0_6 8.do cx @ 1 844 33 @ 3 @ 1 8.1.4 Vacuum sensor Please refer to the separate operating manual of the vacuum sensor! NOTE The vacuum sensor has only a limited service life. Especially carboncontaining substances, e.g. alcoholic compounds, reduce the service life extremely.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 216 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 20 Desinf ektion von Tr ockn ungsk am mer und Zu beh ör @ 25\ mo d_1 4049 841 078 51_ 68.d ocx @ 184 461 @ 2 @ 1 8.2 Disinfection of the drying chamber and accessories • • • • Use commercially-available disinfectants such as, for example, Incidur , Meliseptol , Sagrotan , Buraton , or Terralin (available at specialised trade).
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 218 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 80 Wa rtu ng u nd I nstan dhal tung /08 0-0 021 Wart ung splan Epsilon 6er 10 er @ 25\ mod _14 049 846 8138 5_6 8.d ocx @ 1859 31 @ 2 @ 1 8.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service System/ Component Inspection Detail / Part before start Refrigeration System daily Ice formation Electrical Installation replace X operation calibration cleaning X X X X X X X X X X X Clean regulation device X X X Instrumentation Vacuum sensor(s) T emperature points at FD Pressure sensors chamber Product temperature Level switches Solenoid valves Leakages Max pressure reading Oil in reservoir Hydraulic hoses T ravel speed cylin
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service Pos: 220 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 31 Inst and haltu ngsa rbeit en Epsil on @ 25\ mod _14 049 8410 998 2_6 8.do cx @ 1844 89 @ 2 @ 1 8.4 Service In the event of service work that requires the removal of the panels, there is a risk of electric shock or mechanical injury. Only qualified specialist personnel is authorised to perform this service work.
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Freeze-dryer EPSILON 2-6 LSCplus 8 Maintenance and service 1. Declaration of decontamination As a certified company and due to the legal regulations for the protection of our employees and of the environment, we are obliged to certify the harmlessness of all incoming goods. For this purpose, we require a declaration of decontamination. • The form must be filled in completely and signed by authorised and specialised personnel only.
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Freeze-dryer EPSILON 2-6 LSCplus 9 Disposal Pos: 226 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 90 Ents org ung/ 090 Ents org ung === == == == === == == === == == === == == === == == === == @ 2 5\mo d_1 404 984 138 903 _68. docx @ 18 451 7 @ 1 @ 1 9 Disposal Pos: 227 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 90 Ents org ung/ 090 -00 10 Entso rgu ng d er G efri ertr ockn ungs anlag e @ 25\ mod _140 498 414 112 2_6 8.doc x @ 1 845 31 @ 2 @ 1 9.
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Freeze-dryer EPSILON 2-6 LSCplus 10 Technical data Pos: 232 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -6D LSC plus Sta nda rd/1 00 Tech nisch e Date n/1 00 Tec hnisch e Dat en E2 -6D= == == === == == === == == === == == === == == == @ 25\ mo d_14 049 848 435 51_ 68.
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Freeze-dryer EPSILON 2-6 LSCplus 10 Technical data Connection requirements Electrical connection: 3 x 400 V / 50 Hz (other supply data on request) Protection class: I IP-Code according to DIN 60529: 21 Nominal power: 3.45 kVA Nominal current: 8.0 A Mains fuse: 12 A Equipment connections Vacuum connection: Small flange connection DN25KF (ISO 28403, DIN 2861) Media drain valve: Hose nozzle DN10 (outside diameter 12 mm) Aeration valve: Hose nozzle DN6 (outside diameter 8.
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Freeze-dryer EPSILON 2-6 LSCplus 10 Technical data Pos: 234 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 00 Tech nische D ate n/10 0-0 010 Um geb ungs bedin gun gen -- --- --- -- --- -- --- --- -- --- -- --- -- --- --- -- --- -- @ 25 \mo d_1 404 9841 557 72_ 68.d ocx @ 184 573 @ 2 @ 1 10.1 Umgeb ungs bedi ngu nge n 10.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix Pos: 240 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang /011 0 Anh ang == == === == == == === == == === == == === == == === == == === == == = @ 25\m od_ 140 498 417 799 4_68 .docx @ 1 846 01 @ 1 @ 1 11 Appendix Pos: 241 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang /011 0-0 010 M athe matisc he Zusa mm enh äng e @ 2 5\m od_ 140 498 4178 952 _68 .docx @ 1 8461 5 @ 2 @ 1 11.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix Pos: 243 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -6D LSC plus Sta nda rd/1 10 An han g/01 10- 003 0 Ko nfor mität serkl äru ng 2 -6D_ LSCplus @ 25\ mo d_1 4049 848 528 37_ 68.d ocx @ 186 321 @ 2 @ 1 11.2 EC-Declaration of conformity Pos: 244 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0. docx @ 10 5 @ @ 1 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix Pos: 245 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang /011 0-0 040 Spa nnu ngsriss - u nd Ch emik alienb estä ndigk eit Plexiglas @ 2 5\m od_1 404 984 180 960 _68. docx @ 18 464 3 @ 2 @ 1 110 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix 11.3 Resistance to stress cracking and chemical influences "Plexiglas" Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix 112 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix Pos: 246 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0. docx @ 10 5 @ @ 1 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 11 Appendix Pos: 247 /01 0 Univ ersal mod ule/9 00 Gl ossa r GT Epsilon == === == == === == == == === == == === == == === == == === == @ 2 6\mo d_1 404 986 130 353 _68. docx @ 18 891 7 @ 1 @ 1 128 Version 10/2012, Rev. 1.
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Freeze-dryer EPSILON 2-6 LSCplus 12 Glossary 12 Glossary Aeration, stoppering, storage "Aeration, stopperting, storage" means automated sealing of the product vials with previously inserted rubber stoppers under partial vacuum and subsequent storage on the shelves at defined conditions as an integral part of a freeze-drying program.
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Freeze-dryer EPSILON 2-6 LSCplus 12 Glossary Pressure increase test The pressure increase test can only be carried out with double-chamber method. During the pressure increase test, the intermediate valve prevents the flow of steam from the drying chamber to the ice condenser so that the water vapour of the sublimation cannot flow off. The result is a more or less distinct pressure increase that is measured in the product chamber.
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Freeze-dryer EPSILON 2-6 LSCplus Index 13 Index A Access protection....................................... 59 Accessories ................................... 11, 27, 98 Accident prevention ................................... 25 Actual values of the current process .......... 46 Administration ............................................ 57 Adsorption filter .................................... 33, 35 Aeration medium, preselection ............. 54, 86 Aeration valve ....................................
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Freeze-dryer EPSILON 2-6 LSCplus Index Dialog box "Tools"...................................... 46 Differential pressure between feed flow and return flow ............................................ 106 Dimensions ................................................ 31 Direct hazard to the life and health ............. 24 Disinfectants .............................................. 99 Disinfection of the drying chamber and accessories ............................................
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Freeze-dryer EPSILON 2-6 LSCplus Index LyoBalance weighing system ............... 48, 86 LyoControl LCplus measuring system ........ 86 LyoControl-Rx ............................................ 71 LyoLogplus data logging software .............. 86 M Main drying ................................................ 21 Main window "?"......................................... 67 Main window "Manual" ............................... 44 Main window "Program" ............................. 52 Main window"Options" ....
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Freeze-dryer EPSILON 2-6 LSCplus Index Product temperature measurement system WTMplus ................................................ 86 Program list................................................ 52 Program sections ....................................... 71 Program templates..................................... 81 Protection class........................................ 106 Protection of the environment .................... 25 Protective gloves........................................
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Freeze-dryer EPSILON 2-6 LSCplus Index V Vacuum ..................................................... 71 Vacuum connection ................................. 106 Vacuum pump ...................................... 28, 39 Vacuum pump is not activated ................... 89 Vacuum pump oil change........................... 64 Vacuum pump warm-up ............................. 72 Vacuum pump, cleaning and care .............. 97 Vacuum sensor ..............................