Instruction Manual

ManualsBrandsMartin Christ ManualsEquipmentEpsilon 2-4 LSCplus

Operating Manual

Freeze-dryer

EPSILON 1-4 LSCplus

Part no. 112991, 112993, 112999

EPSILON 2-4 LSCplus

Part no. 112992, 112994, 113000

Translation of the original operating manual

Version 04/2014

Rev. 1.4 of 09/12/2014

EPSILON 1-4 LSCplus;Freeze-dryer;EPSILON 2-4 LSCplus

Freeze-dryer

Summary of content (131 pages)

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Operating Manual Freeze-dryer EPSILON 1-4 LSCplus Part no. 112991, 112993, 112999 EPSILON 2-4 LSCplus Part no. 112992, 112994, 113000 Translation of the original operating manual sb Version 04/2014 Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus In case of inquiries, please state the following numbers: Order number Serial number © Copyright by Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode am Harz Germany Tel.: +49 (0) 5522 / 5007-0 Fax: +49 (0) 5522 / 5007-12 Web: www.martinchrist.de E-mail: info@martinchrist.de Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Table of contents 1 General information ............................................................................................................. 9 1.1 Importance of the operating manual.................................................................................. 9 1.2 Intended use ..................................................................................................................... 9 1.3 Warranty and liability.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Table of contents 4 Storage and transport ....................................................................................................... 31 4.1 Dimensions and weight ................................................................................................... 31 4.2 Storage conditions .......................................................................................................... 31 4.3 Notes on transport .....
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Table of contents 7 Malfunctions and error correction .................................................................................... 85 7.1 General malfunctions ...................................................................................................... 85 7.1.1 Power failure.............................................................................................................. 86 7.1.2 Insufficient vacuum ............
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Table of contents 8 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 1 General information Pos: 1 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n01 0 Allge mein e Inf or matio nen == === == == === == == === == == == === == == @ 24\ mo d_14 049 832 079 82_ 68.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 1 General information Pos: 6 /2 00 C hrist/ 360 GT -BA Lab or-Pilot (STANDARDM ODULE)/ 010 Allg emei ne I nfor mati one n01 0-0 030 Gew ährlei stun g un d Haf tung @ 2 5\m od_ 1404 983 211 377 _68. docx @ 18 296 3 @ 2 @ 1 1.3 Warranty and liability The warranty and liability are subject to our "General Terms and Conditions" that were distributed to the operator upon the conclusion of the contract.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 1 General information Pos: 14 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon 2- 4 LSCplu s Stan dar d/01 0 Allge meine Inf orm ation en/ 010 -00 70 Liefe ru mfan g E1- 4_2 -4 @ 25\ mod _14 049 846 995 21_6 8.d ocx @ 185 945 @ 2 @ 1 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation Pos: 17 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise0 20 Aufba u u nd Wirk ungsw eise= == == == === == == === == == === == = @ 25\ mod_ 140 498 323 599 4_6 8.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation 4 5 6 7 Connections for the product sensors and a LyoRX sensor Shelf Ice condenser Defrosting water collecting tray Fig. 2: Detailed view A – drying chamber 8 Mains switch Fig. 3: Right side of the freeze-dryer Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation 9 Aeration valve 10 Access flange DN40 (e.g. for weighing device, behind the side panel) Fig. 4: Left side of the freeze-dryer Standard: Air-cooled freeze-dryer 11 Name plate 12 Electrical connection of the vacuum sensor 13 Ethernet interface 14 Heat exchanger for the heat transfer medium (behind the panel) 15 Vacuum flange Fig. 5: Rear view of an air-cooled freeze-dryer 14 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation Special equipment: water-cooled freeze-dryer 16 Connector for the cooling water outlet 17 Connector for the cooling water inlet Fig. 6: Rear view of a water-cooled freeze-dryer 18 Vacuum sensor connection 19 Internal fuse 20 Power supply of the pressure control valve 21 Power supply of the vacuum pump 22 Automatic circuit breaker 1F1 23 Equipotential bonding screw Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation Pos: 21 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon 2- 4 LSCplu s Stan dar d/02 0 Aufb au und Wi rkun gsweise /020 -00 10 -002 0 Typ enschild E2-4 @ 2 5\m od_ 1404 984 709 736 _68. docx @ 18 597 3 @ 3 @ 1 2.1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation Pos: 23 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /02 0 Aufb au u nd Wirk ungs weise0 20- 002 0 Wir kun gsweise --- -- --- --- -- --- -- --- -- - @ 2 5\m od_ 140 498 3253 850 _68 .docx @ 18 304 7 @ 2 @ 1 2.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation Melting point pressure curve Pressure (mbar) SOLID A Melting B Sublimation 0.37 mbar V Su apo bl ur im p at res io s n ur pr e es cu su rv re e f cu or rv ice e = 6.11 mbar LIQUID ou Vap r ssu pre e urv re c Evaporation Triple point GASEOUS -30°C Temperature (°C) Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation Pressure (mbar) 1 bar LIQUID Melting point pressure curve 1 SOLID cur ve Triple point Va p su ou bl r p im re at ss io ur n e pr cu es rv su e re for cu ic rv e = e 2 ou Vap ur e ess r pr GASEOUS 20°C Temperature (°C) Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation At the same time, the ice condenser is pre-cooled ("cool-down"). The ice condenser temperature does not have any influence on the product temperature. The sole purpose of the ice condenser is to bind the released water vapour. Pos: 29 / 010 Unive rsalm odul e/Le erzeil e @ 0\mo d_1 202 116 244 500 _0.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation NOTE If the product that is to be dried contains solvents or high salt concentrations, it may start to thaw during the drying process, which is indicated by clearly visible foaming. In order to prevent this, the product must be frozen as deeply as possible, e.g. with the aid of liquid nitrogen, prior to putting it into the unit. Pos: 31 / 010 Unive rsalm odul e/Le erzeil e @ 0\mo d_1 202 116 244 500 _0.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 2 Layout and mode of operation 2.2.2.5 End of drying and aeration The end of the drying process is reached when both the product and shelf temperature are clearly in the positive range (+15 to +20°C) and if their difference is not greater than 5 K. Another indication of the end of the drying process is the behaviour of the vacuum and of the ice condenser temperature.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 41 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 Sicher heit === == == === == == === == == == === == == === == @ 25 \mo d_1 404 983 296 098_ 68. docx @ 18 320 1 @ 1 @ 1 3 Safety Pos: 42 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -001 0 Bes childe run g de s Ge räts @ 25 \mo d_1 404 9832 970 40_ 68. docx @ 183 215 @ 2 @ 1 3.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 44 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -002 0 Sy mbol - un d Hinweis erklä run gen @ 2 5\m od_1 404 983 298 133 _68. docx @ 18 322 9 @ 2 @ 1 3.2 Explanation of the symbols and notes This operating manual uses the following names and symbols to indicate hazards: This symbol stands for a direct hazard to the life and health of persons.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 46 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -003 0 Ve ran twort ung des Be trei bers @ 2 5\m od_1 404 983 299 227 _68. docx @ 18 324 3 @ 2 @ 1 3.3 Responsibility of the operator The operator is responsible to authorise only qualified personnel to work on the freeze-dryer (see chapter 3.4 - "Operating personnel").
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 52 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -006 0 Sich erh eitshinw eise +++ ++ ++ +++ ++ ++ +++ ++ ++ +++ ++ ++ + @ 25\m od_ 140 498 330 236 1_68 .docx @ 1 832 85 @ 2 @ 1 3.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 57 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -006 0- 0020 M echa nische Sicher heit @ 25\ mo d_1 4049 833 045 93_ 68.d ocx @ 183 313 @ 3 @ 1 3.6.2 Mechanical safety In order to ensure the safe operation of the freeze-dryer, please comply with the following points: • • • WARNING • • • • • • • Do not use the freeze-dryer if it was installed incorrectly.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 62 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -006 0- 0030 Bra ndsc hutz @ 25\ mo d_14 049 833 057 08_ 68.d ocx @ 183 327 @ 3 @ 1 3.6.3 Fire prevention Fuses protect certain electrical circuits within the freeze-dryer against overcurrent conditions. • • • DANGER Always use fuses of the same type and rating. Do not dry explosive or inflammable substances.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 70 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit 030 -007 0 Sich erh eitsein richt ung en- --- -- --- -- --- --- -- --- -- --- -- --- --- -- --- -- --- --- -- --- - @ 25\ mod _14 0498 330 911 0_6 8.do cx @ 1 833 69 @ 2 @ 1 3.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 3 Safety Pos: 75 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /03 0 Sicher heit/ 030 -00 82 V erh alten bei G efah re n un d Unf ällen Epsil on mit H2O 2 @ 2 5\m od_ 140 498 331 447 6_68 .docx @ 1 834 39 @ 2 @ 1 3.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 4 Storage and transport Pos: 80 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /04 0 La ger ung und Tr ans port 040 La ger ung un d T rans port == == == === == == === == == === == == @ 25 \mo d_1 404 9837 136 64_ 68.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 4 Storage and transport Pos: 85 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon 2- 4 LSCplu s Stan dar d/04 0 L age rung un d T rans por t/04 0-0 020 T rans por thinw eise E1 -4_2 -4 @ 25\ mo d_1 4049 847 209 79_ 68.d ocx @ 186 001 @ 2 @ 1 4.3 Notes on transport • • • • Use suitable packaging for the transport, and if at all possible, the original packaging. Install all transport safety devices (see chapter 4.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 4 Storage and transport Pos: 87 / 200 Christ /36 1 GT -BA La bor -Pilot (PROJEKTE )/Epsilon 2- 4 LSCplu s Stan dar d/04 0 L age rung un d T rans por t/04 0-0 040 Ver packu ng E1 -4_ 2-4 @ 2 5\mo d_1 404 984 721 900 _68. docx @ 18 601 5 @ 2 @ 1 4.4 Packaging The freeze-dryer is packaged in a wooden crate. • After opening the packaging, take out the accessories. • Remove the packaging material. • Remove the side walls of the crate.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 5 Set-up and connection Pos: 92 / 200 Christ /36 0 GT -BA La bor -Pilot (S TANDARDMODULE) /05 0 Aufstell ung und Anschlus s050 Aufst ellun g un d Anschl uss= == === == == === == == === == == == @ 25\ mo d_14 049 837 372 44_ 68.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 5 Set-up and connection Pos: 100 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -4 LSC plus Sta nda rd/0 50 Auf stellu ng u nd Ansc hluss/ 050 -00 40 Vak uum messs ond e E1- 4_2 -4 @ 25\ mod _14 049 847 357 96_ 68.d ocx @ 186 057 @ 2 @ 1 5.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 5 Set-up and connection Thyracont VSP62/63 MKS 722B Pfeiffer TPR 280/281 Fig. 16: Installed vacuum sensors of different manufacturers The vacuum sensor comes supplied in a calibrated state. NOTE After power-on, the vacuum sensor needs a few minutes to reach its operating temperature. Pos: 101 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 5 Set-up and connection Fig. 17: Example of a door locking system of the loading door; here: door stop (left side) Pos: 104 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0. docx @ 11 4 @ @ 1 Pos: 105 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 50 Aufs tellun g u nd Ansc hluss/0 50- 006 0 Belü ftun gsven til Epsilon @ 25 \mo d_1 404 984 632 770_ 68. docx @ 18 577 7 @ 2 @ 1 5.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 5 Set-up and connection Pos: 107 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -4 LSC plus Sta nda rd/0 50 Auf stellu ng u nd Ansc hluss/ 050 -00 60 Vak uu mpu mpe E 1-4 _2- 4 @ 2 5\m od_ 140 498 473 6896 _68 .docx @ 1 860 71 @ 2 @ 1 5.4.6 Vakuum pum pe 5.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 5 Set-up and connection Pos: 111 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 50 Aufst ellun g un d Anschl uss05 0- 0100 Gu mmiv entile @ 2 5\m od_1 404 983 741 840 _68. docx @ 18 356 5 @ 2 @ 1 5.8 Rubber valves The rubber valves (part no. 121860) enable the connection of round-bottom flasks, wide-neck filter bottles, or distributors for ampoules to a manifold or drying chamber.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Pos: 114 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb0 60 Be trieb == == == === == == === == == === == == === == == == === = @ 25\ mod _14 0498 375 975 8_6 8.do cx @ 1 835 78 @ 1 @ 1 6 Operation Pos: 115 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb0 60 -001 0 Er ste I nbet rieb nah me +++ ++ ++ +++ ++ ++ +++ ++ ++ +++ ++ @ 2 5\mo d_1 404 983 760 674 _68.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Pos: 123 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50 LSCplus Anl age nsteu eru ng Epsil on - -- --- -- --- --- -- --- -- --- --- -- --- -- --- -- --- --- @ 2 5\m od_ 1404 983 956 815 _68. docx @ 18 369 0 @ 2 @ 1 6.5 LSCplus control system The control system LSCplus (Lyo Screen Control plus) was specifically developed for the control of freeze-drying processes.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation The user interface is divided into four main windows that can be called up by touching the corresponding buttons: Manual This window is also the standard user interface. It is used to control the freeze-drying process manually. Program This area is used to create and execute programs for automating the freeze-drying process and for making it reproducible.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Status line (1) This line shows the operating status of the freeze-dryer as well as the active phase. The status line also shows the current date and time. The clock is batterybuffered and must be reset after a failure (see chapter 6.5.1.3 - "Main window "Options"", section "Administration"). In addition, the drive symbol provides information concerning the status of the external data storage device or of the network drive.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Actual values of the current process (4) This area shows the current process data. The fields can be configured as desired: • Select the button of the field that is to be adapted. A dialog box opens: Fig. 24: Dialog box "Select actual value" • Select the desired configuration or quit the dialog box by pressing the "return" button. In this way, it is possible to configure a personalised overview of the actual values.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Option: USB process recording (see chapter 6.6 - "Optional extensions and special equipment") • Select the "Process recording" function in the dialog box "Tools". • Select the input fields ("Batch data"). A keyboard for the data input will be displayed. • If necessary, select the “Options” tab, choose between manual or automatic recording, and define a recording interval.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Fig. 27: Dialog box "Pressure increase test" • The "Test stop" button stops the pressure increase test. Option: LyoBalance weighing system If the freeze-dryer is equipped with a LyoBalance weighing system (see chapter 6.6 - "Optional extensions and special equipment"), then the corresponding parameters must be configured in this dialog box.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Dialog box "Process and equipment messages" (7) This dialog box shows and saves all of the error messages and other messages. In the event of an error or message, the window “Process and equipment messages” will open automatically. In addition, a sound signal is emitted until the error is acknowledged.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Details Touching the message calls up details concerning the error message: • Cause of the message, • Effects of the message, • Measures to eliminate the error, • Reference designator, • Error counter (indicates how often this error has occurred) and the time stamp of the last error message. Use the arrow keys to call up the individual windows. The error message text is always followed by an error code.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation "Dialog box "Operating mode: select/start (8) After the set values have been entered for the process, the process can be started manually with this function (see chapter 6.5.2 - "Manual freezedrying"). Fig. 32: Dialog box "Operating mode: select/start" (The version of the dialog box that is displayed depends on the equipment of the freeze-dryer.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Pos: 130 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50- 001 0-0 021 Hau ptfe nster Prog ra mm Epsil on @ 25\ mod _14 049 839 6583 4_6 8.d ocx @ 183 788 @ 4 @ 1 6.5.1.2 Main window "Program" In the main window "Program", pre-programmed freeze-drying processes can be loaded and edited and new programs can be created with the PGMplus programmer module.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Pos: 132 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50- 001 0-0 031 Hau ptfe nster Opti one n Epsilon - 1 Vakuu mpu mp e @ 2 5\m od_ 140 498 3968 681 _68 .docx @ 1 8381 6 @ 4 @ 1 6.5.1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Change scale unit (2) This dialog box is used to change the unit of measurement for the temperature and vacuum. Fig. 36: Dialog box "Change scale unit" Special equipment: Preselection of the aeration medium (3) This function can be performed in the manual mode or saved together with a program (see chapter 6.5.3.1 - "Creating a program").
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation The following media preselection settings are possible: • Air: Preselects the media connection "Air". • Inert gas: Preselects the media connection "Inert Gas". • Automatic: Automatic media connection preselection depending on the chamber pressure and stoppering status of the product vials: – Chamber pressure 950 mbar: Preselection of the media connection "Air".
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Special equipment: Inertisation (5) (see chapter 6.6 - "Optional extensions and special equipment") In order to start an inertisation process, all of the aeration ports must be connected to the inert gas supply. The aeration valves are disabled during an active inertisation process.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Administration “Administration” options: 1 "Date/Time" 2 "Network" 3 "System properties" 4 "Access protection" 5 "Device options" 6 "Configuration of sensors" 7 "WTMplus configuration" Fig. 40: Dialog box "Options/Administration" Date/Time (1) The LSCplus control system is equipped with an integrated, batterybuffered clock. After a failure of the buffer battery, the date and time must be reset. Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Network (2) This dialog box is used to change various system settings. The modifications will not become effective until after a restart of the unit. NOTE Fig. 42: Dialog box "Network" System properties (3) This dialog box is used to change various system settings. Fig. 43: Dialog box "System properties" Beeper: The beeper sounds in the event of a malfunction, for example.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Click on touch: If this function is active, a clicking sound can be heard whenever the system registers that a button has been touched.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation • The button with the lock symbol blocks the access immediately and the system switches to the default setting. Fig. 46: Access blocked, the data cannot be edited Operator/maintenance/administrator password: For each of these access levels, certain editing rights have been defined.They can be enabled with the corresponding password. The rights of the various access levels are detailed in the following table.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation If the freeze-dryer is to be extended by an option, this option must be enabled via this dialog box. • Press the button "Add option". An input window opens. • Enter the six-digit Christ activation code that was supplied for this option. Note that the keys are case sensitive. Options can be removed in the same way. The modifications will not become effective until after a restart of the unit.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation WTMplus configuration (7) The dialog box is displayed for information purposes only. The configuration can be changed only via the LPCplus user interface. NOTE This dialog box shows all of the existing WTMplus sensors. Every sensor is assigned to a measuring channel based on its serial number.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Service “Service” options: 1 "Operating hours" 2 "Failure memory" 3 "Vacuum pump oil change" 4 "Maintenance" 5 "Sensor adjustment" Fig. 50: Dialog box "Service" (varies depending on the type of system) Operating hours (1) This dialog box is used to call up the number of operating hours of the various components of the freeze-dryer, e.g. the refrigeration unit, vacuum pump, or pressure control valve.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Failure memory (2) The failure memory stores the most recent messages of the process and equipment information system. These messages can be viewed in this dialog box. The failure memory includes the last 32 messages. If this number is exceeded, the oldest message will be overwritten. Use the arrow keys to call up the individual messages. The error message text is always followed by an error code.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Fig. 53: Dialog box "Vacuum pump oil change" Maintenance (5) The maintenance interval of the unit is fixed at 3,000 operating hours or at least one maintenance per year. When the end of a maintenance interval is reached, a corresponding message will be displayed. • Acknowledge the message. • Make an appointment for the maintenance of your freeze-dryer.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Sensor adjustment (6) Misadjusted sensors will lead to incorrect measurement values, which in turn will have a negative effect on the process control. CAUTION In this dialog box, the sensors are adjusted in terms of a predefined reference value. • Press the button in order to select the sensor. A selection menu will be displayed. • Enter a reference value and press the button "Adjust". Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Pos: 134 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 50- 001 0-0 041 Hau ptfe nster "? " Epsilo n @ 25\ mod_ 140 498 397 319 3_6 8.doc x @ 1 838 58 @ 4 @ 1 6.5.1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation In the manual mode, the set values of the active phase can be changed during the process run. In this case, the control system adapts the unit to the new set values as quickly as possible. After the completion of a phase, the system switches to the next phase without switching the unit to standby. The transition from "freezing" to "warm-up" takes place automatically.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Viewing or editing the set values: • Press the button "Set values: view/edit" (see chapter 6.5.1.1 - "Main window "Manual""). The following dialog box will be displayed: 1 2 "Aeration" button "Defrosting" button 3 "Media drain" button (special equipment) "Leakage test" button 4 Fig. 58: Dialog box "Set values: view/edit" Fields that are displayed in the form of buttons can be edited.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Numerical values can be edited with the aid of a numerical keypad: 1 2 Set value display Button for changing the sign (e.g. when entering temperature values) 3 4 " " (infinite) Button for editing the value in pre-defined steps 5 Selection of a possible maximum or minimum value 7 Input of a value via the numerical keypad Button for deleting the displayed value Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Program sections When the programmer module executes a freeze-drying process, it executes the various sections that were created one after the other until the last section is completed. Within the various sections, the system calculates linear ramps for the temperature and vacuum.These ramps start with the set value of the previous section and end with the set value of the current section.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation the set value. If the shelf temperature is beyond the permissible range, the section will be extended until the deviation is within the permissible range. T product: This value defines the permissible deviation of the product temperature (measured by product sensor 1) from the set value. During the freezing phase, the product temperature may exceed the set value by the defined value.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation +30 T/°C Pressure/mbar +20 +10 Section “freezing” Last section “freezing” 100 10 First section “drying” 1 0.1 0 -10 0.01 -20 0.001 t/h Warm-up phase of the vacuum pump Fig. 62: The warm-up phase of the vacuum pump is shifted to the freezing phase prior to the first drying section Pos: 143 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Creating a blank program (1) This button is used to call up a blank program template. Only section 1 is pre-defined as the loading section. In this phase, the start conditions of the programs are defined. The room temperature (20°C) is the standard default. If the product is frozen outside the freeze-dryer (double-chamber method), the shelf temperature must be adapted accordingly in section 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation • Pressing the button “Program name” (2) calls up an input field in which the name of the program can be changed. • The button “Save” (7) can be used in between or at the end of the program creation in order to save the program. • The button “Program” (1) calls up the main window. The system will ask the user whether the program shall be saved if this has not been done yet.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation • • • exceeded, the pressure increase test will be aborted in order to prevent the product from thawing. Progress condition: In the last main drying or final drying section, two pressure increase tests will be performed and evaluated. The start point will be calculated automatically by the control system. The parameters "Duration test" and "Time between tests" apply.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Option: Comparative pressure measurement (see chapter 6.6 - "Optional extensions and special equipment") The indication of the measurement value "dp Comp" can be configured in chapter 6.5.1.1 - "Main window "Manual"" under "Actual values of the current process" in the dialog box "Select actual value". NOTE The comparative pressure measurement can be activated or deactivated by pressing the button in the dialog box.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Option: Aeration, stoppering, storage (see chapter 6.6 - "Optional extensions and special equipment") 1 2 3 4 5 Button for selecting the variant Set value "Aeration" Set value "Aeration after stoppering" Set value "Stoppering" Set value "Storage" Fig.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation stated under "Aeration after stoppering" (see the illustration above, item 3). Then, the shelves are moved apart into the drying position. In the second step, the system is aerated up to atmospheric pressure.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation If the vacuum control system of the freeze-dryer uses a regulated gas admission (injection), the preselected medium will be used for this purpose. If the freeze-dryer is equipped with the "Aeration, Stoppering, Storage" option, the preselected medium will be used for the aeration up to stoppering (backfilling) as well as for the final aeration up to atmospheric pressure.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Fig. 70: Information concerning the program template (here: a recipe for nutrient media/bacteria) After the conformation of the information, the program template will be displayed. • Similar to a blank program, sections can be added or deleted and the set values can be adapted accordingly. Pos: 145 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation 6.5.3.3 Copying a program If a new program is to be created based on an already existing program, the already existing program can be copied. A free program storage location must be available for this purpose. • Select the program to be copied from the list in the main window "Program". • Press the button with the program name in order to call up a window with the program data.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Fig. 72: The freeze-drying process can be started with the aid of the button “Program start”. NOTE • During the freeze-drying process, the description of the active program can also be called up from the main window "Program" and via the button "Info". • When the "Stop" button is pressed, the freeze-dryer switches to the standby – manual freezing mode. The program starts with section 02 "Freezing" by default.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation Pos: 155 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 60 Bet rieb/ LSCplus/ 060 -00 60 Optio nale Erw eite run gen und S onde ra usstatt ung en Epsil on- --- -- --- -- --- --- -- --- -- --- --- -- @ 25 \mo d_1 404 984 006 843_ 68. docx @ 18 4054 @ 2 @ 1 6.6 Optional extensions and special equipment Aeration, stoppering, storage see also chapter 6.5.3.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation USB process recording see also chapter 6.5.2 - "Manual freeze-drying", section "Dialog box "Tools"" This feature enables the recording of a running process on a USB storage medium. After the end of the process recording, the process data can be viewed on the PC with LyoLogplus and they can be printed. It is also possible to import the data directly into an Excel file. Preselection of the aeration medium see also chapter 6.5.1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 6 Operation LPCplus SCADA system The Christ LPCplus system consists of the Supervisory Control And Data Acquisition (SCADA) software program by Martin Christ Gefriertrocknungsanlagen GmbH and a dedicated PC.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 7 Malfunctions and error correction Pos: 161 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche 070 Stör ung en und Fehl ers uche == === == == === == == === == == === = @ 25\ mod _14 049 840 5603 9_6 8.d ocx @ 184 111 @ 1 @ 1 7 Malfunctions and error correction Malfunctions are displayed in the dialog box "Process & equipment messages" (see chapter 7.2 - "Process and error messages").
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 7 Malfunctions and error correction Type of error Possible reason Correction The displayed vacuum value is not correct • Incorrect calibration • • The vacuum sensor is soiled (e.g. due to water residues) The vacuum sensor is defective. • • • Calibrate the vacuum sensor (see the separate operating instructions of the vacuum sensor). Clean the vacuum sensor. Check the vacuum display with the aid of a reference device (if available).
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 7 Malfunctions and error correction Pos: 168 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche 070 -00 10- 002 0 Kein aus reich end es Vaku um @ 25 \mo d_1 404 9840 600 39_ 68.d ocx @ 184 167 @ 3 @ 1 7.1.2 Insufficient vacuum The vacuum checks must be carried out when the ice condenser is frozen. NOTE Pos: 169 /01 0 Univ ersal mod ule/L eerz eile @ 0\m od_ 120 211 624 450 0_0.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 7 Malfunctions and error correction 7.1.2.2 Aeration valve A malfunction of the aeration valve may have several causes. One potential source are contaminants such as product residues within the valve. • Switch the freeze-dryer off and disconnect the mains plug. • Clean the valve (see chapter 8.1.1.3 - "Aeration valve"). • Put the freeze-dryer into operation again.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 7 Malfunctions and error correction Pos: 180 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 70 Stö run gen und Fe hler such e/07 0-0 010 -00 31 Eisko nde nsat or- und Stellfläc hent emp era tur E psilon @ 25\ mo d_1 4049 846 659 83_ 68.d ocx @ 185 861 @ 3 @ 1 7.1.3 Insufficient ice condenser temperature Ensure sufficient ventilation.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 7 Malfunctions and error correction Pos: 184 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 70 Stö run gen und Fe hlers uche /07 0-0 031 Kont akt im S ervice fall_Epsilo n @ 25\m od_ 140 498 406 970 5_68 .docx @ 1 842 93 @ 2 @ 1 7.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 187 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung 080 War tung un d Inst and haltu ng === == == === == == === == == === == = @ 25\ mod _140 498 409 570 4_6 8.doc x @ 1 843 07 @ 1 @ 1 8 Maintenance and service The freeze-dryer and the accessories are subject to high mechanical stress.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 193 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -4 LSC plus Sta nda rd/0 80 Wa rtu ng u nd I nsta ndh altun g/08 0-0 010 -00 10- 001 0 Eisko nde nsato rka mme r ( nur E2-4 ) @ 25\ mod _140 498 475 764 0_6 8.doc x @ 1 861 13 @ 4 @ 1 8.1.1.1 Ice condenser chamber Before each start-up, ensure that the ice condenser chamber is free from water residues.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 197 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -4 LSC plus Sta nda rd/0 80 Wa rtu ng u nd I nsta ndh altun g/08 0-0 010 -00 10- 003 0 Belü ftun gsven til (n ur E2 -4) @ 2 5\m od_1 404 984 758 394 _68. docx @ 18 612 7 @ 4 @ 1 8.1.1.3 1 2 3 Aeration valve Contaminants such as product residues may lead to an insufficient vacuum.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 201 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung 080 -00 10- 002 0 Vak uum pum pe @ 25\ mo d_14 049 841 034 28_ 68.d ocx @ 184 405 @ 3 @ 1 8.1.2 Vacuum pump Please refer to the separate operating manual of the vacuum pump! NOTE The stress of the vacuum pump in conjunction with a freeze-dryer is usually not very high.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 205 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung 080 -00 10- 004 0 Vak uum messs ond e @ 25\m od_ 140 498 410 561 0_68 .docx @ 1 844 33 @ 3 @ 1 8.1.4 Vacuum sensor Please refer to the separate operating manual of the vacuum sensor! NOTE The vacuum sensor has only a limited service life. Especially carboncontaining substances, e.g.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 209 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung 080 -00 20 D esinf ektion von Tr ocknu ngsk amm er und Zu beh ör @ 25\ mod _14 049 841 078 51_6 8.d ocx @ 184 461 @ 2 @ 1 8.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 211 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n Sta nda rd/0 80 Wa rtu ng u nd I nstan dhal tung /08 0-0 020 Wart ung splan Epsilon 4er @ 2 5\m od_1 404 984 679 421 _68. docx @ 18 591 6 @ 2 @ 1 8.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service Pos: 213 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 80 Wa rtun g u nd In stan dhalt ung/ 080 -00 31 Inst and haltu ngsa rbeit en Epsil on @ 25\ mod _14 049 8410 998 2_6 8.do cx @ 1844 89 @ 2 @ 1 8.4 Service In the event of service work that requires the removal of the panels, there is a risk of electric shock or mechanical injury.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 8 Maintenance and service 8.5 Return of defective parts Although we exercise great care during the production of our products, it may be necessary to return a unit or accessory to the manufacturer. In order to ensure the quick and economical processing of returns of freeze-dryers, rotational vacuum concentrators, spare parts, or accessories, we require complete and extensive information concerning the process.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 9 Disposal Pos: 219 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 90 Ents org ung 090 Entso rgu ng= == == === == == == === == == === == == === == == === == == @ 25 \mo d_1 404 9841 389 03_ 68. docx @ 184 517 @ 1 @ 1 9 Disposal Pos: 220 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/0 90 Ents org ung 090 -00 10 En tsor gun g de r G efrie rtr ocknu ngsa nlag e @ 2 5\m od_ 140 498 414 112 2_68 .
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 10 Technical data Pos: 225 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -4 LSC plus Sta nda rd/1 00 Tech nisch e Date n/1 00 Tec hnisch e Dat en E2 -4= == === == == == === == == === == == === == == == @ 25\ mod _14 049 847 700 73_ 68.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 10 Technical data Connection requirements Electrical connection: 1 x 230 V / 50 Hz (other supply data on request) 1 x 230 V / 50 Hz (other supply data on request) Protection class: I I IP-Code according to DIN 60529: 21 21 Nominal power: 1.0 kVA 1.9 kVA Nominal current (without vacuum pump): 4.5 A 8.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 10 Technical data Pos: 227 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 00 Tech nische D ate n10 0-0 010 Umg ebu ngsb edin gun gen --- -- --- --- -- --- -- --- --- -- --- -- --- -- --- --- -- -- @ 25\ mod _14 049 841 557 72_ 68.d ocx @ 184 573 @ 2 @ 1 10.1 Umgeb ungs bedi ngu nge n 10.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Pos: 233 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang 011 0 Anh ang == === == == === == == == === == == === == == === == == === == == == = @ 2 5\m od_ 140 4984 177 994 _68. docx @ 18 460 1 @ 1 @ 1 11 Appendix Pos: 234 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang 011 0-0 010 Ma the matisc he Zusa mm enhä nge @ 2 5\m od_1 404 984 178 952 _68. docx @ 18 461 5 @ 2 @ 1 11.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Pos: 236 /20 0 Ch rist/3 61 G T-BA L abo r-Pilot (PROJEKTE)/Epsilo n 2 -4 LSC plus Sta nda rd/1 10 An han g/01 10- 003 0 Ko nfor mität serkl äru ng 1 -4_ 2-4 LSCplus @ 25 \mo d_1 404 984 777 923_ 68. docx @ 18 615 3 @ 2 @ 1 11.2 EC-Declaration of conformity Pos: 237 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0. docx @ 10 5 @ @ 1 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Pos: 238 /20 0 Ch rist/3 60 G T-BA L abo r-Pilot (STANDARDMODU LE)/1 10 Anh ang 011 0-0 040 Span nun gsriss - un d Ch emikali enb estän digkeit Plexiglas @ 25 \mo d_1 404 984 1809 60_ 68. docx @ 18 4643 @ 2 @ 1 106 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 11.3 Resistance to stress cracking and chemical influences "Plexiglas" Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 108 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 110 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 112 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 114 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 116 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 118 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 120 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix 122 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Pos: 239 /01 0 Univ ersal mod ule/Seit enwec hsel @ 0\m od_ 120 211 624 4312 _0. docx @ 10 5 @ @ 1 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 11 Appendix Pos: 240 /01 0 Univ ersal mod ule9 00 Glo ssar GT E psilon === == == === == == === == == == === == == === == == === == == @ 26 \mo d_1 404 9861 303 53_ 68.d ocx @ 188 917 @ 1 @ 1 124 Version 04/2014, Rev. 1.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 12 Glossary 12 Glossary Aeration, stoppering, storage "Aeration, stopperting, storage" means automated sealing of the product vials with previously inserted rubber stoppers under partial vacuum and subsequent storage on the shelves at defined conditions as an integral part of a freeze-drying program.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus 12 Glossary closes. Then, the actual leakage test is performed in a second step. The leak rate that is calculated after the end of the test provides information concerning the tightness of the system. Pressure increase test The pressure increase test can only be carried out with double-chamber method.
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Index 13 Index A Access protection....................................... 57 Accessories ................................... 11, 27, 95 Accident prevention ................................... 25 Actual values of the current process .......... 44 Administration ............................................ 55 Aeration medium, preselection ............. 52, 83 Aeration valve ....................................
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Index Dimensions ................................................ 31 Direct hazard to the life and health ............. 24 Disinfectants .............................................. 96 Disinfection of the drying chamber and accessories ............................................ 96 Displayed vacuum value is not correct ....... 86 Disposal of the freeze-dryer ..................... 100 Disposal of the packaging ........................
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Index LyoLogplus data logging software .............. 83 M Main drying ................................................ 21 Main window "?"......................................... 65 Main window "Manual" ............................... 42 Main window "Program" ............................. 50 Main window"Options" ............................... 51 Mains fuse ............................................... 102 Maintenance ....................
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Index R Radioactive substances ....................... 28, 91 Rated current ............................................. 16 Reference designator............. 46, 48, 61, 126 Refrigerant ............................................... 101 Refrigerant data ......................................... 16 Registered office ........................................ 16 Remaining hazards ....................................
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Freeze-dryer EPSILON 1-4 LSCplus Freeze-dryer EPSILON 2-4 LSCplus Index Ventilation ............................................ 34, 89 Viewing or editing the set values ................ 67 Volumetric flow rate ................................. 102 W Warranty and liability.................................. 10 Water feed flow temperature .................... 102 Water return flow temperature.................. 102 Water temperature difference................... 102 Weighing system............................