SDS

12
NTP
- Nickel : R
- Iron : Present
- Carbon black : Present
OSHA
- Nickel : Present
- Carbon black : Present
ACGIH
- Nickel : A5
- Aluminum : A4
- Cobalt and cobalt compounds : A3
- Diiron Trioxide : A4
- Carbon black : A3
- Chromium : A4
-Ethylbenzene : A3
KOREA-ISHL
- Lithium Nickel Oxide : 2
- Nickel : 1A
- Cobalt and inorganic compounds : 2
- Carbon black : 2
- Chromium : 1A(Chromium(Ⅵ)compounds(Water insoluble inorganic compounds))
- Ethylbenzene : 2
EU
- Nickel : Carc. 2
- Copper : EPA IRIS: D In carcinogenicity study with rat, tumor was not observed.
- Polyethylene : Fifty rats were implanted with polyethylene. In the polyethylene group, 23 developed tumors (two of these were
unrelated to the implants).
- Boehmite (Al(OH)O) : bauxite and alumina exposure was not associated with increased cancer risk.
- Ethylbenzene : there was clear evidence of carcinogenic activity of ethylbenzene in rat(male/female)with based on increased
Incidences of renal tubule neoplasms; increased incidence of testicular adenoma.
Mutagenicity :
- Graphite : Negative reactions were observed in vitro (Bacterial Reverse Mutation Assay(OECD Guideline 471, GLP)).
- Fe : In mammalian cell gene mutation assay electrolytic iron, positive carbonyl iron exhibited a cytotoxic and mutagenic response
(OECD TG 476)
- Copper : Negative reactions were observed in both in vitro(Ames test) and in vivo(DNA damage and/or repair; unscheduled DNA
synthesis, micronucleus assay). (GLP)
- Aluminum : Negative reactions were observed in vitro (mammalian cell gene mutation assay with mouse lymphoma L5178Y
cells(OECD TG 476, GLP)) and in vivo (micronucleus assay with rats (OECD TG 474, GLP)). (Aluminum hydroxide, aluminium
chloride, aluminum oxide; read across)
- Lithium hexafluorophosphate(1-) : Negative reactions were observed in both in vivo (Mammalian Erythrocyte Micronucleus
test(OECD Guideline 474)) and in vitro (Bacterial Reverse Mutation Assay(OECD Guideline 471, GLP)).
- 4-fluoro-1,3-dioxolan-2-one : Positive reactions were observed in vitro (Bacterial Reverse Mutation Assay(OECD Guideline 471,
GLP)) and Negative reactions were observed in vivo (Mammalian Erythrocyte Micronucleus Test(OECD Guideline 474, GLP)).
- Dimethyl carbonate : Negative reactions were observed in both in vitro (Mammalian Chromosome Aberration Test (OECD Guideline
473, GLP)) and in vivo (Mammalian Spermatogonial Chromosome Aberration Test (OECD Guideline 483))
- Polyethylene : Negative reactions were observed in Ames test using Salmonella typhimurium and Escherichia coli.
- Diiron trioxide : Negative reactions were observed in both in vitro (Mammalian Chromosome Aberration Test (OECD Guideline 473,
GLP)) and in vivo (DNA damage, chromosome aberration and micronuclei induction test)
- Boehmite (Al(OH)O) : Negative reactions were observed in vitro(mammalian cell gene mutation assay(OECD TG 476, GLP),
Negative reactions were observed in vivo Mammalian Erythrocyte Micronucleus Test(OECD TG 474, GLP)
- Carbon black : Negative reactions were observed in both in vitro(Bacterial gene mutation test(OECD TG 471, GLP), Chromosomal
aberrations test(OECD TG 476)) and in vivo(DNA damage and/or repair test).
- Chromium : In vitro mammalian chromosome aberration test, the result of the assay was negative. (Read across; stainless
steel)(OECD TG 473, GLP)
- Lithium carbonate;Lithane : Negative reactions were observed in vitro (Bacterial Reverse Mutation Assay(OECD Guideline 471,
GLP)).
- Ethylbenzene : Negative reactions were observed in in vitro-mammalian chromosome aberration test(OECD TG 473), mammalian
cell gene mutation test (OECD TG 476, GLP) and in vivo- unscheduled DNA synthesis (UDS) test with mammalian liver cells
(OECD TG 486, GLP), mammalian erythrocyte micronucleus test (OECD TG 474, GLP).