SDS

SAMSUNG SDI Co., Ltd.
Date: January 1
st
2020 Revision no.: 01
MODEL INR18650-29E
Page 18 of 29
In the developmental toxicity test using rabbits, adverse effects were not observed, respectively.
(OECD Guideline 414, GLP)
- Ethylene carbonate : In the reproductive toxicity test using mouse, adverse effects were not observed,
respectively. (GLP) In the developmental toxicity test using rabbits, adverse effects were not observed,
respectively. (GLP)
- Lithium hexafluorophosphate(1-) : In the reproductive toxicity and developmental toxicity test using
rats, adverse effects were not observed, respectively. (OECD Guideline 416, GLP)(OECD Guideline
414)
- Graphite : In the reproductive toxicity with rats, there were no significant adverse effects on
reproductive parameters. (OECD Guideline 422, GLP)
- Ethyl methyl carbonate : In the reproductive toxicity and developmental toxicity test using rats,
adverse effects were not observed, respectively. (OECD Guideline 414)
- Nickel : In the reproductive toxicity and developmental toxicity test with rats, the number of live
pups/litter was significantly decreased, pup mortality was significantly increased, and average pup body
weight was significantly decreased at the 500 ppm dose level. (OECD Guideline 416, GLP)
- 1,4-Benzenedicarboxylic acid, 1,4-dimethyl ester, polymer with 1,4-cyclohexanedimethanol and 1,2--
1-methyl-2-pyrrolidone : In the two-generation reproductive toxicity test with rats, developmental toxicity
was evidenced by increased pup mortality and reduced body weight gain, including corresponding
effects in the investigated organs, in pups treated at 500/350 mg/kg bw/day. (NOAEL(F) = 160 mg/kg
bw/day) (OECD Guideline 416, GLP)
- Nickel sulphide : In the reproductive toxicity with rats, the 500 ppm dose caused significant body
weight depression of both mothers and pups and increased neonatal mortality during the postnatal
development period. (equivalent or similar to OECD Guideline 416, GLP) (Nickel Chloride Hexahydrate
(7791-20-0)).
- Silicon : In the reproductive toxicity and developmental toxicity test using rats, adverse effects were
not observed, respectively. (equivalent or similar to OECD Guideline 478) (Read-across; FDA-
Compound 71-41 = Silene, calcium silicate (hydrated))
- Lithium carbonate : In the reproductive toxicity test with rats, no toxicological significant changes were
detected. (OECD Guideline 416, GLP)
- Carbon black : In the reproductive toxicity and developmental toxicity test using mice, adverse effects
were not observed, respectively. (OECD Guideline 414, GLP)
- Succinonitrile : In the reproductive toxicity and developmental toxicity tests with rats, there were no
significant adverse effects on reproductive parameters. (OECD Guideline 416, GLP)
Specific target organ toxicity (single exposure) : Not classified
- Carbon : In the acute oral toxicity test with rats, Animals visible exhibited labored breathing and
intermittent gasping. (OECD Guideline 403)
- Iron : In the acute oral toxicity test with rats, inactivity and depression of the animals within a few
minutes after administration.(OECD Guideline 401, GLP)
- Copper : In the acute oral toxicity test with rats, clinical signs observed included lethargy, prostrate
posture, green coloured diarrhoea, voiding few faeces and moribundity. (OECD Guideline 401, GLP) In
the acute inhalation toxicity test with rats, slight to moderate ataxia, slight to moderate tremor and slight
to moderate dyspnoea were observed. (OECD Guideline 436, GLP)
- Aluminium : In the acute oral toxicity test using rats, adverse effects were not observed, respectively.
(Read-across)(OECD Guideline 401) In the acute inhalation toxicity test using rats, adverse effects
were not observed, respectively. (OECD Guideline 403)