SDS

SAMSUNG SDI Co., Ltd.
Date: January 1
st
2020 Revision no.: 01
MODEL INR18650-29E
Page 17 of 29
- Polyethylene : No toxicity was observed in in vitro mutagenicity test using Salmonella typhimurium
strain.
- Ethylene carbonate : Negative reactions were observed in vitro (Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP)).
- Lithium hexafluorophosphate(1-) : Negative reactions were observed in both in vivo (Mammalian
Erythrocyte Micronucleus Test(OECD Guideline 474)) and in vitro (Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP)).
- Graphite : Negative reactions were observed in in vitro test(Bacterial Reverse Mutation Assay(OECD
Guideline 471, GLP)).
- Ethyl methyl carbonate : Negative reactions were observed in vitro (Mammalian Chromosome
Aberration Test (OECD Guideline 473, GLP))
- 1-methyl-2-pyrrolidone : Negative reactions were observed in in vitro tests(Bacterial Reverse Mutation
Assay(OECD Guideline 471), Mammalian Gene Mutation Test(OECD Guideline 476, GLP) and DNA
Damage and/or Repair Study(OECD Guideline 482, GLP)).
Negative reactions were observed in in vivo tests(Mammalian Erythrocyte Micronucleus Test(OECD
Guideline 474, GLP) and Mammalian Bone Marrow chromosome Aberration Test(OECD Guideline
475, GLP)).
- Nickel sulphide : Posiive reactions were observed in in vivo mammalian germ cell study.(Read-
across)
- Silicon : Negative reactions were observed in both in vivo (Mammalian Bone Marrow Chromosome
Aberration Test(OECD Guideline 475, GLP))
- Trade secret 2 : Negative reactions were observed in in vivo (Mammalian Erythrocyte Micronucleus
Test(OECD Guideline 474, GLP)).
- Lithium carbonate : Negative reactions were observed in in vivo genetic toxicity test.
- Carbon black : Positive reactions were observed in both in vitro (Chromosomal aberrations test
(OECD Guideline 476, GLP)) and in vivo (ypoxanthine-guanine phosphoribosyl transferase gene (hprt)
mutations in alveolar epithelial cells).
- Succinonitrile : Negative reactions were observed in in vitro tests(Bacterial Reverse Mutation
Assay(OECD Guideline 471, GLP) and Mammalian Chromosome Aberration Test(OECD Guideline
473, GLP)). Negative reactions were observed in in vivo tests(Mammalian Erythrocyte Micronucleus
Test(OECD Guideline 474, GLP))
Reproductive toxicity : Not classified
- Copper : In the reproductive toxicity and developmental toxicity test with rats, there were no significant
adverse effects on reproductive parameters and no evidence of malformations at any doses. (OECD
Guideline 416, 414, GLP)
- Aluminium : In the reproductive toxicity and developmental toxicity test using rats, adverse effects
were not observed, respectively. (OECD Guideline 422, GLP)(OECD Guideline 414)
- Cobalt lithium dioxide : In the reproductive toxicity and developmental toxicity screening tests with
rats, treatment with 300 mg cobalt powder/kg bw/day resulted in an increase of the post-implantation
loss and a decrease in the live birth index. Treatment with 30 mg cobalt powder/kg bw/day resulted that
the mean litter weight of pups was slightly reduced in a dose-related way (not significant at p ≤ 0.01),
significant only at 300 mg cobalt powder/kg bw/day. (NOAEL(P, F1) = 30 mg/kg bw/day) (OECD
Guideline 422, GLP)
- Dimethyl carbonate : In the reproductive toxicity test using rats, adverse effects were not observed,
respectively. (OECD Guideline 415, GLP)