Datasheet

MSDS-No.: 169788
V004.1
Loctite 431
Page 9 of 13
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
negative
bacterial reverse
mutation assay (e.g
Ames test)
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Bis(2-hydroxy-3-tert-
butyl-5-
methylphenyl)methane
119-47-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Hydroquinone
123-31-9
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
EU Method B.13/14
(Mutagenicity)
Repeated dose toxicity
Hazardous components
CAS-No.
Result
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Hydroquinone
123-31-9
NOAEL=>= 250
mg/kg
oral: gavage
14 days 5 days/week.
12 doses
rat
OECD Guideline 407
(Repeated Dose 28-Day Oral
Toxicity in Rodents)
SECTION 12: Ecological information
General ecological information:
Biological and Chemical Oxygen Demands (BOD and COD) are insignificant.
The mixture is classified based on the available hazard information for the ingredients as defined in the classification criteria
for mixtures for each hazard class or differentiation in Annex I to Regulation 1272/2008/EC. Relevant available
health/ecological information for the substances listed under Section 3 is provided in the following.
12.1. Toxicity
Ecotoxicity:
Do not empty into drains / surface water / ground water.