Datasheet
MSDS-No.: 169788
V004.1
Loctite 431
Page 8 of 13
Inhalative toxicity:
May cause respiratory irritation.
Prolonged exposure to high concentrations of vapours may lead to chronic effects in sensitive individuals
In dry atmosphere with < 50% humidity, vapours may irritate the eyes and respiratory system
Skin irritation:
Causes skin irritation.
Bonds skin in seconds. Considered to be of low toxicity: acute dermal LD50 (rabbit)>2000mg/kg
Due to polymerisation at the skin surface allergic reaction is unlikely to occur
Eye irritation:
Causes serious eye irritation.
Liquid product will bond eyelids. In a dry atmosphere (RH<50%) vapours may cause irritation and lachrymatory effect
Acute oral toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
LD50
> 5.000 mg/kg
oral
rat
OECD Guideline 401 (Acute
Oral Toxicity)
Hydroquinone
123-31-9
LD50
367 mg/kg
oral
rat
OECD Guideline 401 (Acute
Oral Toxicity)
Acute inhalative toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Acute dermal toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
LD50
> 2.000 mg/kg
dermal
rabbit
OECD Guideline 402 (Acute
Dermal Toxicity)
Skin corrosion/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
slightly irritating
24 h
rabbit
OECD Guideline 404 (Acute
Dermal Irritation / Corrosion)
Serious eye damage/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
irritating
72 h
rabbit
OECD Guideline 405 (Acute
Eye Irritation / Corrosion)
Respiratory or skin sensitization:
Hazardous components
CAS-No.
Result
Test type
Species
Method
Ethyl 2-cyanoacrylate
7085-85-0
not sensitising
guinea pig
Hydroquinone
123-31-9
sensitising
Guinea pig
maximisat
ion test
guinea pig
Dibenzoyl peroxide
94-36-0
sensitising
Mouse
local
lymphnod
e assay
(LLNA)
mouse
OECD Guideline 429 (Skin
Sensitisation: Local Lymph
Node Assay)










