Datasheet

SDS No.: 316211 V010.0
Loctite 243
Page 14 of 20
Carcinogenicity
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous components
CAS-No.
Result
Route of
application
Exposure
time /
Frequency
of treatment
Species
Sex
Method
maleic acid
110-16-7
not carcinogenic
oral: feed
2 y
daily
rat
male/female
OECD Guideline 451
(Carcinogenicity
Studies)
Reproductive toxicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Test type
Route of
application
Species
Method
maleic acid
110-16-7
NOAEL F1 150 mg/kg
NOAEL F2 55 mg/kg
Two
generation
study
oral: gavage
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
STOT-single exposure:
No data available.
STOT-repeated exposure::
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result / Value
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
Cumene hydroperoxide
80-15-9
inhalation:
aerosol
6 h/d
5 d/w
rat
not specified
maleic acid
110-16-7
NOAEL >= 40 mg/kg
oral: feed
90 d
daily
rat
OECD Guideline 408
(Repeated Dose 90-Day
Oral Toxicity in Rodents)
Aspiration hazard:
No data available.