Datasheet

SDS No.: 316211 V010.0
Loctite 243
Page 13 of 20
Acute inhalative toxicity:
No substance data available.
No data available.
Skin corrosion/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
Cumene hydroperoxide
80-15-9
corrosive
rabbit
Draize Test
maleic acid
110-16-7
irritating
24 h
human
Patch Test
Serious eye damage/irritation:
The mixture is classified based on calculation method referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Exposure
time
Species
Method
2-[[2,2-bis[[(1-
oxoallyl)oxy]methyl]buto
xy]methyl]-2-ethyl-1,3-
propanediyl diacrylate
94108-97-1
Category 2
(irritant)
rabbit
EU Method B.5 (Acute Toxicity: Eye Irritation /
Corrosion)
maleic acid
110-16-7
highly
irritating
rabbit
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
Respiratory or skin sensitization:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Test type
Species
Method
Tetramethylene
dimethacrylate
2082-81-7
sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
maleic acid
110-16-7
sensitising
Mouse local lymphnode
assay (LLNA)
mouse
OECD Guideline 429 (Skin Sensitisation:
Local Lymph Node Assay)
maleic acid
110-16-7
sensitising
Mouse local lymphnode
assay (LLNA)
guinea pig
OECD Guideline 406 (Skin Sensitisation)
Germ cell mutagenicity:
The mixture is classified based on threshold limits referring to the classified substances present in the mixture.
Hazardous substances
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Tetramethylene
dimethacrylate
2082-81-7
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Tetramethylene
dimethacrylate
2082-81-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Tetramethylene
dimethacrylate
2082-81-7
positive
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Cumene hydroperoxide
80-15-9
positive
bacterial reverse
mutation assay (e.g
Ames test)
without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
maleic acid
110-16-7
negative
bacterial reverse
mutation assay (e.g
Ames test)
no data
Ames Test
maleic acid
110-16-7
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)