Safety data sheet

MSDS-No.: 173071
V007.0
LOCTITE SF 7200 known as Loctite 7200
Page 15 of 21
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Propane
74-98-6
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Propane
74-98-6
negative
Drosophila
melanogaster
not specified
Propan-2-ol
67-63-0
negative with
metabolic
activation
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Propan-2-ol
67-63-0
negative
intraperitoneal
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Ethanol
64-17-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
in vitro mammalian
chromosome
aberration test
without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Ethanol
64-17-5
negative
OECD Guideline 475
(Mammalian Bone Marrow
Chromosome Aberration Test)
2-aminoethanol
141-43-5
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
in vitro mammalian
chromosome
aberration test
without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
2-aminoethanol
141-43-5
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Butanone
78-93-3
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Carcinogenicity:
Hazardous components
CAS-No.
Result
Species
Sex
Exposure
timeFrequenc
y of treatment
Route of
application
Method
Propan-2-ol
67-63-0
rat
male/female
104 w
6 h/d, 5 d/w
inhalation:
vapour
OECD Guideline 451
(Carcinogenicity Studies)
Ethanol
64-17-5
rat
oral:
unspecified
not specified
Ethanol
64-17-5
mouse
female
dermal
not specified
Ethanol
64-17-5
mouse
male
inhalation
not specified