Safety data sheet

MSDS-No.: 326229
V005.0
LOCTITE SF 7900 AE 400ML
Page 13 of 18
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Acetone
67-64-1
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
negative
mammalian cell
gene mutation assay
without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
Acetone
67-64-1
negative
oral: drinking water
mouse
not specified
Butane, n- (< 0.1 %
butadiene)
106-97-8
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Butane, n- (< 0.1 %
butadiene)
106-97-8
negative
Drosophila
melanogaster
not specified
Propane
74-98-6
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
in vitro mammalian
chromosome
aberration test
with and without
OECD Guideline 473 (In vitro
Mammalian Chromosome
Aberration Test)
Propane
74-98-6
negative
Drosophila
melanogaster
not specified
Butanone
78-93-3
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Carcinogenicity:
Hazardous components
CAS-No.
Result
Species
Sex
Exposure
timeFrequenc
y of treatment
Route of
application
Method
Acetone
67-64-1
not carcinogenic
mouse
female
424 d
3 times per
week
dermal
not specified