Certifications 2

MSDS-No.: 173097
V004.0
LOCTITE 640
Page 13 of 17
Reproductive toxicity:
Hazardous substances
CAS-No.
Result / Classification
Species
Exposure
time
Species
Method
2,2'-Ethylenedioxydiethyl
dimethacrylate
109-16-0
NOAEL P = 1.000 mg/kg
NOAEL F1 = 1.000 mg/kg
oral: gavage
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction /
Developmental Toxicity
Screening Test)
Hydroxypropyl
methacrylate
27813-02-1
NOAEL P = 400 mg/kg
two-
generation
study
oral: gavage
until one day
before
sacrifice
rat
OECD Guideline 416 (Two-
Generation Reproduction
Toxicity Study)
Repeated dose toxicity
Hazardous components
CAS-No.
Result
Route of
application
Exposure time /
Frequency of
treatment
Species
Method
2,2'-Ethylenedioxydiethyl
dimethacrylate
109-16-0
NOAEL=1.000
mg/kg
oral: gavage
daily
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction / Developmental
Toxicity Screening Test)
Hydroxypropyl
methacrylate
27813-02-1
NOAEL=300
mg/kg
oral: gavage
rat
OECD Guideline 422
(Combined Repeated Dose
Toxicity Study with the
Reproduction / Developmental
Toxicity Screening Test)
Cumene hydroperoxide
80-15-9
inhalation:
aerosol
6 h/d5 d/w
rat
not specified
SECTION 12: Ecological information
General ecological information:
The mixture is classified based on the available hazard information for the ingredients as defined in the classification criteria for
mixtures for each hazard class or differentiation in Annex I to Regulation (EC) No 1272/2008. Relevant available
health/ecological information for the substances listed under Section 3 is provided in the following.
Precautions required with respect to Environmental Hazards of articles in which this product is used should be considered.
12.1. Toxicity
Ecotoxicity:
Harmful to aquatic life with long lasting effects.
Do not empty into drains / surface water / ground water.