Certifications 2

MSDS-No.: 173097
V004.0
LOCTITE 640
Page 11 of 17
Acute oral toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
2,2'-Ethylenedioxydiethyl
dimethacrylate
109-16-0
LD50
10.837 mg/kg
oral
rat
not specified
Hydroxypropyl
methacrylate
27813-02-1
LD50
> 2.000 mg/kg
oral
rat
OECD Guideline 401 (Acute
Oral Toxicity)
Acrylic acid
79-10-7
LD50
1.500 mg/kg
oral
rat
BASF Test
Cumene hydroperoxide
80-15-9
LD50
550 mg/kg
oral
rat
not specified
Methacrylic acid
79-41-4
LD50
1.320 mg/kg
oral
rat
OECD Guideline 401 (Acute
Oral Toxicity)
Acute inhalative toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Acrylic acid
79-10-7
LC50
> 5,1 mg/l
Vapor.
4 h
rat
OECD Guideline 403 (Acute
Inhalation Toxicity)
Acrylic acid
79-10-7
Acute
toxicity
estimate
(ATE)
11 mg/l
vapour
Expert judgement
Methacrylic acid
79-41-4
LC50
> 3,6 mg/l
aerosol
4 h
rat
OECD Guideline 403 (Acute
Inhalation Toxicity)
Acute dermal toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
2,2'-Ethylenedioxydiethyl
dimethacrylate
109-16-0
LD50
> 2.000 mg/kg
dermal
mouse
not specified
Hydroxypropyl
methacrylate
27813-02-1
LD50
> 5.000 mg/kg
dermal
rabbit
not specified
Acrylic acid
79-10-7
Acute
toxicity
estimate
(ATE)
1.100 mg/kg
dermal
Expert judgement
Acrylic acid
79-10-7
LD50
> 2.000 mg/kg
rabbit
OECD Guideline 402 (Acute
Dermal Toxicity)
Cumene hydroperoxide
80-15-9
LD50
1.200 - 1.520
mg/kg
dermal
not specified
Methacrylic acid
79-41-4
Acute
toxicity
estimate
(ATE)
500 mg/kg
dermal
Expert judgement
Methacrylic acid
79-41-4
LD50
500 - 1.000
mg/kg
rabbit
Dermal Toxicity Screening
Skin corrosion/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
2,2'-Ethylenedioxydiethyl
dimethacrylate
109-16-0
not irritating
24 h
rabbit
Draize Test
Hydroxypropyl
methacrylate
27813-02-1
not irritating
24 h
rabbit
Draize Test
Acrylic acid
79-10-7
highly corrosive
3 min
rabbit
OECD Guideline 404 (Acute
Dermal Irritation / Corrosion)
Cumene hydroperoxide
80-15-9
corrosive
rabbit
Draize Test
Methacrylic acid
79-41-4
Category 1A (corrosive)
4 h
rabbit
OECD Guideline 404 (Acute
Dermal Irritation / Corrosion)