Certifications 2
MSDS-No.: 153630
V005.0
LOCTITE LB 8023 MARINE GRADE ANTI-SEIZE known as Marine
Grade Anti-Seize
Page 9 of 13
Acute dermal toxicity:
Hazardous components
CAS-No.
Value
type
Value
Route of
application
Exposure
time
Species
Method
Calcium oxide
1305-78-8
LD50
> 2.500 mg/kg
dermal
rabbit
OECD Guideline 402 (Acute
Dermal Toxicity)
Sulfonic acids, petroleum,
calcium salts
61789-86-4
LD50
> 4.000 mg/kg
dermal
rabbit
other guideline:
Boron oxide (B2O3)
1303-86-2
LD50
> 2.000 mg/kg
dermal
rabbit
Skin corrosion/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Sulfonic acids, petroleum,
calcium salts
61789-86-4
not irritating
4 h
rabbit
OECD Guideline 404 (Acute
Dermal Irritation / Corrosion)
Boron oxide (B2O3)
1303-86-2
not irritating
24 h
rabbit
Serious eye damage/irritation:
Hazardous components
CAS-No.
Result
Exposure
time
Species
Method
Sulfonic acids, petroleum,
calcium salts
61789-86-4
not irritating
rabbit
OECD Guideline 405 (Acute
Eye Irritation / Corrosion)
Boron oxide (B2O3)
1303-86-2
not irritating
rabbit
OECD Guideline 405 (Acute
Eye Irritation / Corrosion)
Respiratory or skin sensitization:
Hazardous components
CAS-No.
Result
Test type
Species
Method
Sulfonic acids, petroleum,
calcium salts
61789-86-4
sensitising
Buehler
test
guinea pig
OECD Guideline 406 (Skin
Sensitisation)
Boron oxide (B2O3)
1303-86-2
not sensitising
Buehler
test
guinea pig
OECD Guideline 406 (Skin
Sensitisation)
Germ cell mutagenicity:
Hazardous components
CAS-No.
Result
Type of study /
Route of
administration
Metabolic
activation /
Exposure time
Species
Method
Sulfonic acids, petroleum,
calcium salts
61789-86-4
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
Boron oxide (B2O3)
1303-86-2
negative
bacterial reverse
mutation assay (e.g
Ames test)
with and without
OECD Guideline 471
(Bacterial Reverse Mutation
Assay)
negative
mammalian cell
gene mutation assay
with and without
OECD Guideline 476 (In vitro
Mammalian Cell Gene
Mutation Test)
negative
sister chromatid
exchange assay in
mammalian cells
with and without
Boron oxide (B2O3)
1303-86-2
negative
oral: gavage
mouse
OECD Guideline 474
(Mammalian Erythrocyte
Micronucleus Test)
Carcinogenicity:
Hazardous components
CAS-No.
Result
Species
Sex
Exposure
timeFrequenc
y of treatment
Route of
application
Method
Boron oxide (B2O3)
1303-86-2
not carcinogenic
mouse
male/female
103 w
daily
oral: feed
OECD Guideline 451
(Carcinogenicity Studies)